Color changes were also observed as the reaction evolved, which could be attributed to the
aldimine binding reactions (CH = N) that occur when an aldehyde group (-CHO) reacts with an amino group during the crosslinking process.
In the catalysis of PLP-dependent enzymes, the transaldimination reaction is strictly conserved and happens at least two times in forward and reverse directions: the forward reaction is from the internal
aldimine to the external
aldimine and the reverse reaction is vice versa (Scheme 1).
Hydroamination of alkyne 2 with amine 6 yields the
aldimine intermediate 7.
Dnyanpeeth, "Synthesis and pharmacological activities of 4-carboxaldehyde and its
aldimines derivatives," Asian Journal of Chemistry, vol.
(16.) Subramania, A, Kalyana Sundaram, NT, Sathiya Priya, R, Saminathan, K, Muralidharan, VS, Vasudevan, T, "
Aldimines Effective Corrosion Inhibitors for Mild Steel in Hydrochloric Acid Solution." J.
Baruah, "Participation of self-generated polyaniline support in copper(II) catalysed oxidative reaction of phenyl
aldimines," Journal of Molecular Catalysis A, vol.
Choudary, "Synthesis of a-amino nitriles through Strecker reaction of
aldimines and ketoimines by using nanocrystalline magnesium oxide," Tetrahedron, vol.
Imines [11], both
aldimines and ketimines due to presence of carbon-nitrogen bond in their molecules, provides a potential site for chemical [12-13] as well as biological [14-15] activity, but very less work has been carried out on synthesis of [alpha],[beta]-unsaturated ketimines.
In addition, cure rates can be lowered by utilizing blocked NHs (i.e.,
aldimines and ketimines) that become active upon reacting with atmospheric moisture and/or formulating with ASP-based secondary diamines.
The aim of the present work was to fill this gap and investigate the pinacol coupling of
aldimines in the presence of mischmetall (Ce and La), Zn-Cu couple, and Dewarda alloy (50% Cu, 5% Zn, 45% Al).