(Q64899599)

http://europepmc.org/abstract/PMC/6545365

30 June 2019

review article

1 reference

title

Emerging Function and Clinical Values of Exosomal MicroRNAs in Cancer. (English)

1 reference

http://europepmc.org/abstract/PMC/6545365

30 June 2019

author name string

Man Wang

1

1 reference

http://europepmc.org/abstract/PMC/6545365

30 June 2019

Fei Yu

2

1 reference

http://europepmc.org/abstract/PMC/6545365

30 June 2019

Han Ding

3

1 reference

http://europepmc.org/abstract/PMC/6545365

30 June 2019

Yu Wang

4

1 reference

http://europepmc.org/abstract/PMC/6545365

30 June 2019

Peifeng Li

5

1 reference

http://europepmc.org/abstract/PMC/6545365

30 June 2019

Kun Wang

6

1 reference

http://europepmc.org/abstract/PMC/6545365

30 June 2019

publication date

15 May 2019

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http://europepmc.org/abstract/PMC/6545365

30 June 2019

published in

Molecular Therapy. Nucleic acids

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http://europepmc.org/abstract/PMC/6545365

30 June 2019

volume

16

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http://europepmc.org/abstract/PMC/6545365

30 June 2019

page(s)

791-804

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http://europepmc.org/abstract/PMC/6545365

30 June 2019

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Exosomes derived from hypoxic leukemia cells enhance tube formation in endothelial cells

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12 December 2020

Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs

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12 December 2020

Ovarian cancer cell invasiveness is associated with discordant exosomal sequestration of Let-7 miRNA and miR-200

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12 December 2020

Deregulated microRNAs in gastric cancer tissue-derived mesenchymal stem cells: novel biomarkers and a mechanism for gastric cancer

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12 December 2020

Exosome-formed synthetic microRNA-143 is transferred to osteosarcoma cells and inhibits their migration

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12 December 2020

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12 December 2020

Tumor-derived exosomes promote tumor progression and T-cell dysfunction through the regulation of enriched exosomal microRNAs in human nasopharyngeal carcinoma

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https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Exosomes from bone marrow mesenchymal stem cells contain a microRNA that promotes dormancy in metastatic breast cancer cells.

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https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Exosomal miR-221/222 enhances tamoxifen resistance in recipient ER-positive breast cancer cells

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https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Exosomal shuttling of miR-126 in endothelial cells modulates adhesive and migratory abilities of chronic myelogenous leukemia cells

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12 December 2020

miR-34a is an intracellular and exosomal predictive biomarker for response to docetaxel with clinical relevance to prostate cancer progression

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https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Endogenous RNAs modulate microRNA sorting to exosomes and transfer to acceptor cells

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12 December 2020

Nontemplated nucleotide additions distinguish the small RNA composition in cells from exosomes

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

Targeting exosomes from preadipocytes inhibits preadipocyte to cancer stem cell signaling in early-stage breast cancer

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12 December 2020

Loss of miR-200 family in 5-fluorouracil resistant colon cancer drives lymphendothelial invasiveness in vitro

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12 December 2020

Exosomes in development, metastasis and drug resistance of breast cancer

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12 December 2020

Understanding the Mysterious M2 Macrophage through Activation Markers and Effector Mechanisms

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12 December 2020

lncRNAs and microRNAs with a role in cancer development

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12 December 2020

Exosomal levels of miRNA-21 from cerebrospinal fluids associated with poor prognosis and tumor recurrence of glioma patients

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https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Pancreatic cancer-derived exosomes transfer miRNAs to dendritic cells and inhibit RFXAP expression via miR-212-3p

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https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

STAT3-regulated exosomal miR-21 promotes angiogenesis and is involved in neoplastic processes of transformed human bronchial epithelial cells

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https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Multiple Roles of MicroRNA-100 in Human Cancer and its Therapeutic Potential

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https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Exosome-mediated transfer of miR-222 is sufficient to increase tumor malignancy in melanoma.

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https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Diagnostic and prognostic relevance of circulating exosomal miR-373, miR-200a, miR-200b and miR-200c in patients with epithelial ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Exosomes Derived from Hypoxic Oral Squamous Cell Carcinoma Cells Deliver miR-21 to Normoxic Cells to Elicit a Prometastatic Phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Exosomal transfer of stroma-derived miR21 confers paclitaxel resistance in ovarian cancer cells through targeting APAF1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Epithelial ovarian cancer-secreted exosomal miR-222-3p induces polarization of tumor-associated macrophages

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https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Exosome-mediated small RNA delivery for gene therapy

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https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Shikonin Inhibits the Proliferation of Human Breast Cancer Cells by Reducing Tumor-Derived Exosomes

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https://pubmed.ncbi.nlm.nih.gov/31163321

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Modification of tumor cell exosome content by transfection with wt-p53 and microRNA-125b expressing plasmid DNA and its effect on macrophage polarization.

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https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Exosomal miR-24-3p impedes T-cell function by targeting FGF11 and serves as a potential prognostic biomarker for nasopharyngeal carcinoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Ubiquitous Release of Exosomal Tumor Suppressor miR-6126 from Ovarian Cancer Cells.

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https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

MicroRNA in Control of Gene Expression: An Overview of Nuclear Functions

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https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Serum exosomal miR-4772-3p is a predictor of tumor recurrence in stage II and III colon cancer

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https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Role of exosomes in the protection of cellular homeostasis.

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https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

A novel signaling role for miR-451 in esophageal tumor microenvironment and its contribution to tumor progression.

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https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Human adipose mesenchymal stem cell-derived exosomal-miRNAs are critical factors for inducing anti-proliferation signalling to A2780 and SKOV-3 ovarian cancer cells

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https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Exosomal microRNA miR-1246 induces cell motility and invasion through the regulation of DENND2D in oral squamous cell carcinoma

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https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Circulating exosomal microRNA-96 promotes cell proliferation, migration and drug resistance by targeting LMO7.

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https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Cell-free methylation markers with diagnostic and prognostic potential in hepatocellular carcinoma

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https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Exosomal MicroRNA Transport from Salivary Mesenchyme Regulates Epithelial Progenitor Expansion during Organogenesis.

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https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Cancer-associated fibroblasts release exosomal microRNAs that dictate an aggressive phenotype in breast cancer

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https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Circulating Plasma and Exosomal microRNAs as Indicators of Drug-Induced Organ Injury in Rodent Models

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https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

MVP-mediated exosomal sorting of miR-193a promotes colon cancer progression

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https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Prognostic role of circulating exosomal miRNAs in multiple myeloma

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https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

TWEAK-stimulated macrophages inhibit metastasis of epithelial ovarian cancer via exosomal shuttling of microRNA.

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https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Loss of exosomal miR-320a from cancer-associated fibroblasts contributes to HCC proliferation and metastasis

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https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Exosomal transfer of tumor-associated macrophage-derived miR-21 confers cisplatin resistance in gastric cancer cells

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https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Exosomal miR-940 maintains SRC-mediated oncogenic activity in cancer cells: a possible role for exosomal disposal of tumor suppressor miRNAs

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Hypoxic lung cancer-secreted exosomal miR-23a increased angiogenesis and vascular permeability by targeting prolyl hydroxylase and tight junction protein ZO-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Exosomal microRNA in plasma as a non-invasive biomarker for the recurrence of non-small cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Cisplatin-resistant lung cancer cell-derived exosomes increase cisplatin resistance of recipient cells in exosomal miR-100-5p-dependent manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Exosomes derived from hypoxic epithelial ovarian cancer deliver microRNA-940 to induce macrophage M2 polarization.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Evaluation of Tumor-Derived Exosomal miRNA as Potential Diagnostic Biomarkers for Early-Stage Non-Small Cell Lung Cancer Using Next-Generation Sequencing

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

MiR-146a-5p level in serum exosomes predicts therapeutic effect of cisplatin in non-small cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

MicroRNA-100 shuttled by mesenchymal stem cell-derived exosomes suppresses in vitro angiogenesis through modulating the mTOR/HIF-1α/VEGF signaling axis in breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Exosomal miR-9-3p suppresses HBGF-5 expression and is a functional biomarker in hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

MicroRNAs in Serum Exosomes as Potential Biomarkers in Clear-cell Renal Cell Carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

HCV-E2 inhibits hepatocellular carcinoma metastasis by stimulating mast cells to secrete exosomal shuttle microRNAs

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Horizontal transfer of miR-23a from hypoxic tumor cell colonies can induce angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Plasma exosomal miRNAs-based prognosis in metastatic kidney cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Serum exosomal miR-301a as a potential diagnostic and prognostic biomarker for human glioma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Liver kinase B1 restoration promotes exosome secretion and motility of lung cancer cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

MicroRNA-6869-5p acts as a tumor suppressor via targeting TLR4/NF-κB signaling pathway in colorectal cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Exosomal MicroRNA MiR-1246 Promotes Cell Proliferation, Invasion and Drug Resistance by Targeting CCNG2 in Breast Cancer

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https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Exosomal miR-6803-5p as potential diagnostic and prognostic marker in colorectal cancer

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https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Decreased levels of serum exosomal miR-638 predict poor prognosis in hepatocellular carcinoma.

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https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Exosomal microRNAs derived from colorectal cancer-associated fibroblasts: role in driving cancer progression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Low plasma levels of miR-101 are associated with tumor progression in gastric cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

https://pubmed.ncbi.nlm.nih.gov/31163321

1 reference

12 December 2020

Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Circulating Exosomal miR-17-5p and miR-92a-3p Predict Pathologic Stage and Grade of Colorectal Cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

MicroRNA-1246 is an exosomal biomarker for aggressive prostate cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Cancer-secreted hsa-miR-940 induces an osteoblastic phenotype in the bone metastatic microenvironment via targeting ARHGAP1 and FAM134A.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Colorectal cancer cell-derived exosomes containing miR-10b regulate fibroblast cells via the PI3K/Akt pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Metastasis-associated miR-23a from nasopharyngeal carcinoma-derived exosomes mediates angiogenesis by repressing a novel target gene TSGA10.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Usefulness of Plasma Exosomal MicroRNA-451a as a Noninvasive Biomarker for Early Prediction of Recurrence and Prognosis of Non-Small Cell Lung Cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Exosomal miR-675 from metastatic osteosarcoma promotes cell migration and invasion by targeting CALN1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Hepatoma cell-secreted exosomal microRNA-103 increases vascular permeability and promotes metastasis by targeting junction proteins.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Cancer-cell-secreted exosomal miR-105 promotes tumour growth through the MYC-dependent metabolic reprogramming of stromal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Exosomal miR-423-5p targets SUFU to promote cancer growth and metastasis and serves as a novel marker for gastric cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Clinical significance of blood-based miRNAs as biomarkers of non-small cell lung cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Exosome-encapsulated microRNA-223-3p as a minimally invasive biomarker for the early detection of invasive breast cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Exosomal Non-Coding RNAs: Diagnostic, Prognostic and Therapeutic Applications in Cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Exosomes in cancer: small vesicular transporters for cancer progression and metastasis, biomarkers in cancer therapeutics.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Hypoxic Tumor-Derived Exosomal miR-301a Mediates M2 Macrophage Polarization via PTEN/PI3Kγ to Promote Pancreatic Cancer Metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Exosomes of glioma cells deliver miR-148a to promote proliferation and metastasis of glioblastoma via targeting CADM1miR-148a effect on glioma cells by CADM1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Exosomal miR-9 inhibits angiogenesis by targeting MDK and regulating PDK/AKT pathway in nasopharyngeal carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Loss of XIST in Breast Cancer Activates MSN-c-Met and Reprograms Microglia via Exosomal miRNA to Promote Brain Metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Transfer of miRNA in Macrophage-Derived Exosomes Induces Drug Resistance in Pancreatic Adenocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Sphk2 RNAi nanoparticles suppress tumor growth via downregulating cancer cell derived exosomal microRNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Exosomal transfer of miR-151a enhances chemosensitivity to temozolomide in drug-resistant glioblastoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Exosome-mediated miR-200b promotes colorectal cancer proliferation upon TGF-β1 exposure

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Loss of exosomal miR-148b from cancer-associated fibroblasts promotes endometrial cancer cell invasion and cancer metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Metabolic reprogramming of stromal fibroblasts by melanoma exosome microRNA favours a pre-metastatic microenvironment

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Downregulation of exosome-encapsulated miR-548c-5p is associated with poor prognosis in colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

miR-590-3p is a novel microRNA which suppresses osteosarcoma progression by targeting SOX9

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Upregulation of microRNA-129-5p inhibits cell invasion, migration and tumor angiogenesis by inhibiting ZIC2 via downregulation of the Hedgehog signaling pathway in cervical cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

MicroRNA-140-5p suppresses retinoblastoma cell growth via inhibiting c-Met/AKT/mTOR pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Effect of exosomal miRNA on cancer biology and clinical applications

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

Exosomes: from carcinogenesis and metastasis to diagnosis and treatment of gastric cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/31163321

12 December 2020

10.1016/J.OMTN.2019.04.027

Identifiers

DOI

1 reference

http://europepmc.org/abstract/PMC/6545365

30 June 2019

PMC publication ID

6545365

1 reference

http://europepmc.org/abstract/PMC/6545365

30 June 2019

PubMed publication ID

31163321

1 reference