(Q47745236)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15093544%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

title

Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15093544%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15093544%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

1

David A Tuveson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15093544%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

18

Ronald A DePinho

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15093544%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

19

Tyler Jacks

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15093544%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

10

Denise Crowley

1 reference

27 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15093544%20AND%20SRC:MED&resulttype=core&format=json

author name string

Alice T Shaw

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15093544%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Nicholas A Willis

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15093544%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Daniel P Silver

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15093544%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Erica L Jackson

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15093544%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Sandy Chang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15093544%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Kim L Mercer

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15093544%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Rebecca Grochow

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15093544%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Hanno Hock

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15093544%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Tal Zaks

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15093544%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Catrina King

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15093544%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Michael A Jacobetz

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15093544%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Lifu Wang

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15093544%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Roderick T Bronson

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15093544%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Stuart H Orkin

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15093544%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

publication date

1 April 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15093544%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15093544%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15093544%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15093544%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

page(s)

375-387

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15093544%20AND%20SRC:MED&resulttype=core&format=json

The ras gene family and human carcinogenesis

27 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

Somatic activation of oncogenic Kras in hematopoietic cells initiates a rapidly fatal myeloproliferative disorder

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

Conditional expression of oncogenic K-ras from its endogenous promoter induces a myeloproliferative disease

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

E1A signaling to p53 involves the p19(ARF) tumor suppressor

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

p53 alteration is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

Somatic activation of the K-ras oncogene causes early onset lung cancer in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

Tumor suppression by Ink4a-Arf: progress and puzzles

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

Expression and phosphorylation of mitogen-activated protein kinases during spermatogenesis and epididymal sperm maturation in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

RAS oncogenes: the first 30 years.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

D-type cyclin-dependent kinase activity in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

Murine fibroblasts lacking p21 undergo senescence and are resistant to transformation by oncogenic Ras.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

Inducible gene knockouts in the small intestinal and colonic epithelium

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

Guanine nucleotide-binding activity as an assay for src protein of rat-derived murine sarcoma viruses

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

Role of the INK4a locus in tumor suppression and cell mortality.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

Chronic myelogenous leukemia: mechanisms underlying disease progression.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

Self-excising retroviral vectors encoding the Cre recombinase overcome Cre-mediated cellular toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

Density dependent inhibition of cell growth in culture

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

Cellular commitment to oncogene-induced transformation or apoptosis is dependent on the transcription factor IRF-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

Cell cycle-dependent activation of Ras.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

The magical touch: genome targeting in epidermal stem cells induced by tamoxifen application to mouse skin

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

Increasing complexity of the Ras signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

Cre-mediated gene deletion in the mammary gland

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

Senescence of human fibroblasts induced by oncogenic Raf.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2804%2900085-6

7 January 2021

10.1016/S1535-6108(04)00085-6

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15093544%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

1 reference