(Q41514660)

2 October 2017

1 reference

title

The complexity of signaling pathways activated by the BCR. (English)

1 reference

2 October 2017

DeFranco AL

1

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2 October 2017

publication date

1 June 1997

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Current Opinion in Immunology

2 October 2017

published in

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2 October 2017

volume

9

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2 October 2017

issue

3

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2 October 2017

page(s)

296-308

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Lymphocyte Development: Intrinsic checkpoints for lineage progression

2 October 2017

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Signaling pathways for antigen receptor-mediated induction of transcription factor CREB in B lymphocytes

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The mechanism of action of cyclosporin A and FK506

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7 January 2021

Cyclosporin-A sensitive induction of NF-AT in murine B cells

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7 January 2021

Cyclosporin A and FK506 inhibit activation-induced cell death in the murine WEHI-231 B cell line

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Signaling pathways activated by protein tyrosine phosphorylation in lymphocytes

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A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-gamma 2.

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7 January 2021

CD22 associates with protein tyrosine phosphatase 1C, Syk, and phospholipase C-gamma(1) upon B cell activation

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Hyperresponsive B cells in CD22-deficient mice

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CD22 regulates thymus-independent responses and the lifespan of B cells.

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7 January 2021

CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-deficient mice.

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7 January 2021

CD22 is a negative regulator of B-cell receptor signalling

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7 January 2021

Association of p72syk with the src homology-2 (SH2) domains of PLC gamma 1 in B lymphocytes

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7 January 2021

Phospholipase C-gamma1 interacts with conserved phosphotyrosyl residues in the linker region of Syk and is a substrate for Syk

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7 January 2021

GRB2 and phospholipase C-gamma 1 associate with a 36- to 38-kilodalton phosphotyrosine protein after T-cell receptor stimulation

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7 January 2021

Tyrosine phosphorylation of Grb2-associated proteins correlates with phospholipase C gamma 1 activation in T cells

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7 January 2021

Cloning and characterization of Lnk, a signal transduction protein that links T-cell receptor activation signal to phospholipase C gamma 1, Grb2, and phosphatidylinositol 3-kinase

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7 January 2021

Antigen-induced B lymphocyte activation involves the p21ras and ras.GAP signaling pathway.

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7 January 2021

A ternary complex factor-dependent mechanism mediates induction of egr-1 through selective serum response elements following antigen receptor cross-linking in B lymphocytes

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7 January 2021

Regulation of transcription by MAP kinase cascades

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7 January 2021

Role of EGR1 in regulation of stimulus-dependent CD44 transcription in B lymphocytes

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7 January 2021

Transcriptional regulation of the Icam-1 gene in antigen receptor- and phorbol ester-stimulated B lymphocytes: role for transcription factor EGR1.

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7 January 2021

Activation of the p21ras pathway couples antigen receptor stimulation to induction of the primary response gene egr-1 in B lymphocytes

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7 January 2021

Reconstitution of B cell antigen receptor-induced signaling events in a nonlymphoid cell line by expressing the Syk protein-tyrosine kinase

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7 January 2021

B cell antigen receptor cross-linking induces tyrosine phosphorylation and membrane translocation of a multimeric Shc complex that is augmented by CD19 co-ligation

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7 January 2021

Signal transduction in T lymphocytes using a conditional allele of Sos

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7 January 2021

Interaction of Shc with the zeta chain of the T cell receptor upon T cell activation

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7 January 2021

In vitro characterization of major ligands for Src homology 2 domains derived from protein tyrosine kinases, from the adaptor protein SHC and from GTPase-activating protein in Ramos B cells

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7 January 2021

Distinct mechanisms mediate SHC association with the activated and resting B cell antigen receptor

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7 January 2021

Tyrosine phosphorylation of Shc is mediated through Lyn and Syk in B cell receptor signaling

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7 January 2021

Interaction of Shc with Grb2 regulates association of Grb2 with mSOS

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7 January 2021

Stimulation through the T cell receptor induces Cbl association with Crk proteins and the guanine nucleotide exchange protein C3G

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7 January 2021

Shc contains two Grb2 binding sites needed for efficient formation of complexes with SOS in B lymphocytes

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7 January 2021

Activators and effectors of ras p21 proteins

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7 January 2021

Interactions between Ras proteins and their effectors

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7 January 2021

Association between GTPase activators for Rho and Ras families.

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7 January 2021

p62(dok): a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells

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7 January 2021

Identification of the Abl- and rasGAP-associated 62 kDa protein as a docking protein, Dok

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7 January 2021

CD19 of B Cells as a Surrogate Kinase Insert Region to Bind Phosphatidylinositol 3-Kinase

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7 January 2021

The CD19/CR2/TAPA-1 complex of B lymphocytes: linking natural to acquired immunity

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7 January 2021

Activation of phosphatidylinositol-3' kinase by Src-family kinase SH3 binding to the p85 subunit

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7 January 2021

Activation of Src-like protein-tyrosine kinase Lyn and its association with phosphatidylinositol 3-kinase upon B-cell antigen receptor-mediated signaling

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7 January 2021

Distinct p53/56lyn and p59fyn domains associate with nonphosphorylated and phosphorylated Ig-alpha

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7 January 2021

B-cell antigen receptor motifs have redundant signalling capabilities and bind the tyrosine kinases PTK72, Lyn and Fyn.

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7 January 2021

Activation-induced association of a 145-kDa tyrosine-phosphorylated protein with Shc and Syk in B lymphocytes and macrophages

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7 January 2021

Negative signaling via FcgammaRIIB1 in B cells blocks phospholipase Cgamma2 tyrosine phosphorylation but not Syk or Lyn activation

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7 January 2021

Crosslinking of surface immunoglobulin and Fc receptors on B lymphocytes inhibits stimulation of inositol phospholipid breakdown via the antigen receptors

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7 January 2021

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

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7 January 2021

A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain.

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7 January 2021

Complex complexes: signaling at the TCR.

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7 January 2021

A novel phosphotyrosine-binding domain in the N-terminal transforming region of Cbl interacts directly and selectively with ZAP-70 in T cells

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7 January 2021

The protein product of the c-cbl protooncogene is phosphorylated after B cell receptor stimulation and binds the SH3 domain of Bruton's tyrosine kinase

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7 January 2021

Specific association of the beta isoform of the p85 subunit of phosphatidylinositol-3 kinase with the proto-oncogene c-cbl

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7 January 2021

Oct-1 protein promotes functional transcription complex assembly on the mouse mammary tumor virus promoter

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7 January 2021

p120cbl is a major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with Fyn and Syk tyrosine kinases, Grb2 and Shc adaptors, and the p85 subunit of phosphatidylinositol 3-kinase

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7 January 2021

Sos, Vav, and C3G participate in B cell receptor-induced signaling pathways and differentially associate with Shc-Grb2, Crk, and Crk-L adaptors

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7 January 2021

B cell antigen receptor signaling induces the formation of complexes containing the Crk adapter proteins

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7 January 2021

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7 January 2021

Physical and functional association of the cbl protooncogen product with an src-family protein tyrosine kinase, p53/56lyn, in the B cell antigen receptor-mediated signaling

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7 January 2021

Vav: function and regulation in hematopoietic cell signaling

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7 January 2021

Faciogenital dysplasia protein (FGD1) and Vav, two related proteins required for normal embryonic development, are upstream regulators of Rho GTPases

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7 January 2021

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

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7 January 2021

Sounding the alarm: protein kinase cascades activated by stress and inflammation

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7 January 2021

Involvement of stress-activated protein kinase and p38 mitogen-activated protein kinase in mIgM-induced apoptosis of human B lymphocytes

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7 January 2021

Activation of AP-1 in primary B lymphocytes by surface immunoglobulin requires de novo Jun-B synthesis

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7 January 2021

A functional T-cell receptor signaling pathway is required for p95vav activity

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7 January 2021

Transcriptional regulation of the IL-2 gene

1 reference

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7 January 2021

Functional and physical interactions of Syk family kinases with the Vav proto-oncogene product

1 reference

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7 January 2021

Identification of HS1 protein as a major substrate of protein-tyrosine kinase(s) upon B-cell antigen receptor-mediated signaling

1 reference

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7 January 2021

Antigen-receptor induced clonal expansion and deletion of lymphocytes are impaired in mice lacking HS1 protein, a substrate of the antigen-receptor-coupled tyrosine kinases

1 reference

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7 January 2021

Restoration of surface IgM-mediated apoptosis in an anti-IgM-resistant variant of WEHI-231 lymphoma cells by HS1, a protein-tyrosine kinase substrate

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7 January 2021

C3d of complement as a molecular adjuvant: bridging innate and acquired immunity

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7 January 2021

Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor Fc(gamma)RIIB.

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7 January 2021

Recruitment and activation of PTP1C in negative regulation of antigen receptor signaling by Fc gamma RIIB1.

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7 January 2021

Cell cycle-specific induction of Cdk2 expression in B lymphocytes following antigen receptor cross-linking

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7 January 2021

Induction of cell cycle regulatory proteins in anti-immunoglobulin-stimulated mature B lymphocytes

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7 January 2021

Cyclin G2 is up-regulated during growth inhibition and B cell antigen receptor-mediated cell cycle arrest

1 reference

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7 January 2021

Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation

1 reference

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7 January 2021

10.1016/S0952-7915(97)80074-X

Identifiers

DOI

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2 October 2017

1 reference