(Q36533782)

English

Molecular basis of immortalization of human mesenchymal stem cells by combination of p53 knockdown and human telomerase reverse transcriptase overexpression

scientific article published on 21 August 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Molecular basis of immortalization of human mesenchymal stem cells by combination of p53 knockdown and human telomerase reverse transcriptase overexpression (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

1 reference

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author name string

Tong Ming Liu

1

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Wei Ming Ng

2

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Hwee San Tan

3

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Denslin Vinitha

4

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Zheng Yang

5

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Jia Bing Fan

6

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Yu Zou

7

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

James H Hui

8

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Eng Hin Lee

9

1 reference

Europe PubMed Central

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14 August 2017

Bing Lim

10

1 reference

Europe PubMed Central

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14 August 2017

language of work or name

1 reference

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21 August 2012

1 reference

Europe PubMed Central

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14 August 2017

Stem Cells and Development

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

22

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

2

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

268-278

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Zinc-finger protein 145, acting as an upstream regulator of SOX9, improves the differentiation potential of human mesenchymal stem cells for cartilage regeneration and repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545350

30 September 2017

Overexpression of hTERT increases stem-like properties and decreases spontaneous differentiation in human mesenchymal stem cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545350

30 September 2017

p53 plays a role in mesenchymal differentiation programs, in a cell fate dependent manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545350

30 September 2017

Replicative senescence of mesenchymal stem cells: a continuous and organized process

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545350

30 September 2017

Cdc20: a WD40 activator for a cell cycle degradation machine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545350

30 September 2017

Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545350

30 September 2017

Knockdown of p53 combined with expression of the catalytic subunit of telomerase is sufficient to immortalize primary human ovarian surface epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545350

30 September 2017

Stem cells and ageing. The potential of stem cells to overcome age-related deteriorations of the body in regenerative medicine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545350

30 September 2017

Combination of hTERT and bmi-1, E6, or E7 induces prolongation of the life span of bone marrow stromal cells from an elderly donor without affecting their neurogenic potential.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545350

30 September 2017

Tissue distribution and engraftment of human mesenchymal stem cells immortalized by human telomerase reverse transcriptase gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545350

30 September 2017

Development and functional characterization of human bone marrow mesenchymal cells immortalized by enforced expression of telomerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545350

30 September 2017

Multilineage differentiation of adult human bone marrow progenitor cells transduced with human papilloma virus type 16 E6/E7 genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545350

30 September 2017

Clonal heterogeneity in differentiation potential of immortalized human mesenchymal stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545350

30 September 2017

In vitro cartilage formation by human adult stem cells from bone marrow stroma defines the sequence of cellular and molecular events during chondrogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545350

30 September 2017

Surfing the p53 network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545350

30 September 2017

Multilineage potential of adult human mesenchymal stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545350

30 September 2017

The human RAD54 recombinational DNA repair protein is a double-stranded DNA-dependent ATPase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545350

30 September 2017

Extension of life-span by introduction of telomerase into normal human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545350

30 September 2017

Stable overexpression of PML alters regulation of cell cycle progression in HeLa cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545350

30 September 2017

Bone formation by human postnatal bone marrow stromal stem cells is enhanced by telomerase expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545350

28 June 2018

Deficiency in p53 but not retinoblastoma induces the transformation of mesenchymal stem cells in vitro and initiates leiomyosarcoma in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545350

21 September 2018

p53 negatively regulates expression of FoxM1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545350

21 September 2018

Identification of common pathways mediating differentiation of bone marrow- and adipose tissue-derived human mesenchymal stem cells into three mesenchymal lineages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545350

21 September 2018

Absence of the p53 tumor suppressor gene promotes osteogenesis in mesenchymal stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545350

21 September 2018

Spontaneous human adult stem cell transformation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545350

21 September 2018

Study of telomere length reveals rapid aging of human marrow stromal cells following in vitro expansion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545350

21 September 2018

Telomerase expression extends the proliferative life-span and maintains the osteogenic potential of human bone marrow stromal cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545350

21 September 2018

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545350

21 September 2018

In vitro chondrogenesis of bone marrow-derived mesenchymal progenitor cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545350

21 September 2018

Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3545350

4 December 2018

Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span

1 reference

https://pubmed.ncbi.nlm.nih.gov/22765508

12 December 2020

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Identifiers

10.1089/SCD.2012.0222

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

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