(Q35925028)

English

Recurrent G-to-A substitution in a single codon of SREBP cleavage-activating protein causes sterol resistance in three mutant Chinese hamster ovary cell lines.

scientific article published in November 1996

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8942999%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

Recurrent G-to-A substitution in a single codon of SREBP cleavage-activating protein causes sterol resistance in three mutant Chinese hamster ovary cell lines (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8942999%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

1

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21 October 2019

author name string

X Hua

2

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21 October 2019

M S Brown

3

1 reference

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21 October 2019

J L Goldstein

4

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21 October 2019

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1 November 1996

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21 October 2019

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8942999%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

93

1 reference

Europe PubMed Central

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21 October 2019

24

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Europe PubMed Central

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21 October 2019

13709-13714

1 reference

Europe PubMed Central

PMC publication ID

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21 October 2019

Sterol resistance in CHO cells traced to point mutation in SREBP cleavage-activating protein

1 reference

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2 October 2017

Sterol-regulated release of SREBP-2 from cell membranes requires two sequential cleavages, one within a transmembrane segment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19399

2 October 2017

Complementation of mutation in acyl-CoA:cholesterol acyltransferase (ACAT) fails to restore sterol regulation in ACAT-defective sterol-resistant hamster cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19399

2 October 2017

Sterol regulatory element binding protein binds to a cis element in the promoter of the farnesyl diphosphate synthase gene

1 reference

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2 October 2017

SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene

1 reference

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2 October 2017

SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis

1 reference

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2 October 2017

The ancient regulatory-protein family of WD-repeat proteins

1 reference

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2 October 2017

Assignment of the membrane attachment, DNA binding, and transcriptional activation domains of sterol regulatory element-binding protein-1 (SREBP-1)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19399

2 October 2017

Three different rearrangements in a single intron truncate sterol regulatory element binding protein-2 and produce sterol-resistant phenotype in three cell lines. Role of introns in protein evolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19399

2 October 2017

Molecular Cloning and Functional Analysis of the Promoter of the Human Squalene Synthase Gene

1 reference

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2 October 2017

Hairpin orientation of sterol regulatory element-binding protein-2 in cell membranes as determined by protease protection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19399

2 October 2017

Membrane-bound domain of HMG CoA reductase is required for sterol-enhanced degradation of the enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19399

2 October 2017

A receptor-mediated pathway for cholesterol homeostasis

1 reference

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2 October 2017

Somatic cell genetics and the study of cholesterol metabolism

1 reference

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2 October 2017

Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms

1 reference

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2 October 2017

Regulation of the mevalonate pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19399

2 October 2017

Sterol-resistant transcription in CHO cells caused by gene rearrangement that truncates SREBP-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19399

27 July 2018

Loss of transcriptional repression of three sterol-regulated genes in mutant hamster cells.

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19399

27 July 2018

19 October 2022

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The intracellular targeting and membrane topology of 3-hydroxy-3-methylglutaryl-CoA reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19399

27 July 2018

A 25-hydroxycholesterol-resistant cell line deficient in acyl-CoA: cholesterol acyltransferase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19399

27 July 2018

Genetic distinction between sterol-mediated transcriptional and posttranscriptional control of 3-hydroxy-3-methylglutaryl-coenzyme A reductase

1 reference

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27 July 2018

Sterol synthesis in variant Chinese hamster lung cells selected for resistance to 25-hydroxycholesterol. Cross-resistance to 7-ketocholesterol, 20alpha-hydroxycholesterol, and serum

1 reference

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27 July 2018

Molecular Dissection of the Role of the Membrane Domain in the Regulated Degradation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase

1 reference

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24 September 2018

Regulation of cytosolic acetoacetyl coenzyme A thiolase, 3-hydroxy-3-methylglutaryl coenzyme A synthase, 3-hydroxy-3-methylglutaryl coenzyme A reductase, and mevalonate kinase by low density lipoprotein and by 25-hydroxycholesterol in Chinese hamste

1 reference

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24 September 2018

Inhibition of Sterol Synthesis in Cultured Mouse Cells by Cholesterol Derivatives Oxygenated in the Side Chain

1 reference

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24 September 2018

Domain structure of 3-hydroxy-3-methylglutaryl coenzyme A reductase, a glycoprotein of the endoplasmic reticulum

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutational specificities of 1'-acetoxysafrole, N-benzoyloxy-N-methyl-4-aminoazobenzene, and ethyl methanesulfonate in human cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8942999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and inhibition of growth of human fibroblasts by 7-ketocholesterol

1 reference

https://pubmed.ncbi.nlm.nih.gov/8942999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms and biomarkers of genotoxicity. Molecular dosimetry of chemical mutagens

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.93.24.13709

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8942999%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

1996PNAS...9313709N

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1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8942999%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8942999%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

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