(Q35550688)

8 August 2017

1 reference

title

The dynamics of chromosome organization and gene regulation (English)

1 reference

8 August 2017

The Dynamics of Chromosome Organization and Gene Regulation (English)

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.72.121801.161724

18 March 2024

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.72.121801.161724

18 March 2024

1

David L Spector

1 reference

8 August 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14527325

18 March 2024

publication date

1 January 2003

1 reference

full work available at URL

8 August 2017

number of pages

36

1 reference

based on heuristic

inferred from page(s)

http://repository.cshl.edu/26357/1/Spector%20Ann%20Rev%20Biocheml%202003.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14527325

https://www.annualreviews.org/doi/pdf/10.1146/annurev.biochem.72.121801.161724

18 March 2024

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.72.121801.161724

Annual Review of Biochemistry

18 March 2024

published in

1 reference

8 August 2017

volume

72

1 reference

8 August 2017

page(s)

573-608

1 reference

Cajal body dynamics and association with chromatin are ATP-dependent

8 August 2017

cites work

1 reference

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18 March 2024

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Macromolecular domains within the cell nucleus

18 March 2024

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Structure and Function in the Nucleus

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Translating the Histone Code

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Protein dynamics: implications for nuclear architecture and gene expression.

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Rabl's model of the interphase chromosome arrangement tested in Chinese hamster cells by premature chromosome condensation and laser-UV-microbeam experiments

18 March 2024

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Three-dimensional architecture of a polytene nucleus

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Three-dimensional organization of Drosophila melanogaster interphase nuclei. I. Tissue-specific aspects of polytene nuclear architecture

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Characteristic folding pattern of polytene chromosomes in Drosophila salivary gland nuclei

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21

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Spatial organization of chromosomes in the salivary gland nuclei of Drosophila melanogaster

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23

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Specific interactions of chromatin with the nuclear envelope: positional determination within the nucleus in Drosophila melanogaster

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24

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Fluorescence in situ hybridization to interphase cell nuclei in suspension allows flow cytometric analysis of chromosome content and microscopic analysis of nuclear organization

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25

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Detection of chromosome aberrations in metaphase and interphase tumor cells by in situ hybridization using chromosome-specific library probes

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Movement of the X chromosome in epilepsy

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Cytogenetic analysis by in situ hybridization with fluorescently labeled nucleic acid probes

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Fluorescence in situ hybridization with human chromosome-specific libraries: detection of trisomy 21 and translocations of chromosome 4.

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Chromosome territories, nuclear architecture and gene regulation in mammalian cells

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Precise Spatial Positioning of Chromosomes During Prometaphase: Evidence for Chromosomal Order

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Evidence for a relatively random array of human chromosomes on the mitotic ring

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Differences in the localization and morphology of chromosomes in the human nucleus.

18 March 2024

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The spatial organization of human chromosomes within the nuclei of normal and emerin-mutant cells.

18 March 2024

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Re-modelling of nuclear architecture in quiescent and senescent human fibroblasts

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Quiescence in nuclear transfer

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Non-random radial higher-order chromatin arrangements in nuclei of diploid human cells

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Evolutionary conservation of chromosome territory arrangements in cell nuclei from higher primates.

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Transient inhibition of histone deacetylation alters the structural and functional imprint at fission yeast centromeres.

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Association of chromosome territories with the nuclear matrix. Disruption of human chromosome territories correlates with the release of a subset of nuclear matrix proteins

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Active and inactive genes localize preferentially in the periphery of chromosome territories

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The 3D positioning of ANT2 and ANT3 genes within female X chromosome territories correlates with gene activity.

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Transcription sites are not correlated with chromosome territories in wheat nuclei

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A specific conformation of the territory of chromosome 17 locates ERBB-2 sequences to a DNase-hypersensitive domain at the nuclear periphery

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Protein dynamics in the nuclear compartment

18 March 2024

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The glucocorticoid receptor: rapid exchange with regulatory sites in living cells

18 March 2024

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FRAP reveals that mobility of oestrogen receptor-alpha is ligand- and proteasome-dependent

18 March 2024

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TBP dynamics in living human cells: constitutive association of TBP with mitotic chromosomes

18 March 2024

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Kinetics of core histones in living human cells: little exchange of H3 and H4 and some rapid exchange of H2B.

18 March 2024

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Structure and dynamic properties of a glucocorticoid receptor-induced chromatin transition

18 March 2024

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Ligand-mediated assembly and real-time cellular dynamics of estrogen receptor alpha-coactivator complexes in living cells

18 March 2024

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Disassembly of transcriptional regulatory complexes by molecular chaperones

18 March 2024

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Regional and temporal specialization in the nucleus: a transcriptionally-active nuclear domain rich in PTF, Oct1 and PIKA antigens associates with specific chromosomes early in the cell cycle

18 March 2024

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Subnuclear partitioning and functional regulation of the Pit-1 transcription factor

18 March 2024

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Interrelationships of nuclear structure and transcriptional control: functional consequences of being in the right place at the right time

18 March 2024

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Cajal bodies: the first 100 years

18 March 2024

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Newly assembled snRNPs associate with coiled bodies before speckles, suggesting a nuclear snRNP maturation pathway

18 March 2024

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The transcriptional role of PML and the nuclear body

18 March 2024

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In vivo binding of active heat shock transcription factor 1 to human chromosome 9 heterochromatin during stress.

18 March 2024

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Human chromosomes 9, 12, and 15 contain the nucleation sites of stress-induced nuclear bodies

18 March 2024

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Transcription-dependent redistribution of the large subunit of RNA polymerase II to discrete nuclear domains

18 March 2024

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A hyperphosphorylated form of the large subunit of RNA polymerase II is associated with splicing complexes and the nuclear matrix

18 March 2024

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The cellular organization of gene expression

18 March 2024

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Intron-dependent recruitment of pre-mRNA splicing factors to sites of transcription

18 March 2024

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In vivo evidence that transcription and splicing are coordinated by a recruiting mechanism

18 March 2024

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Purification and biochemical characterization of interchromatin granule clusters

18 March 2024

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P-TEFb, a cyclin-dependent kinase controlling elongation by RNA polymerase II

18 March 2024

133

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The cdk7-cyclin H-MAT1 complex associated with TFIIH is localized in coiled bodies.

18 March 2024

136

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Purification and characterization of FBI-1, a cellular factor that binds to the human immunodeficiency virus type 1 inducer of short transcripts.

18 March 2024

137

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FBI-1 can stimulate HIV-1 Tat activity and is targeted to a novel subnuclear domain that includes the Tat-P-TEFb-containing nuclear speckles

18 March 2024

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Higher order nuclear organization: three-dimensional distribution of small nuclear ribonucleoprotein particles

18 March 2024

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Organization of highly acetylated chromatin around sites of heterogeneous nuclear RNA accumulation

18 March 2024

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Dynamic relocation of chromosomal protein HMG-17 in the nucleus is dependent on transcriptional activity

18 March 2024

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Compartmentalization within the nucleus: discovery of a novel subnuclear region

18 March 2024

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Of coiled bodies, gems, and salmon

18 March 2024

145

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Coiled bodies contain U7 small nuclear RNA and associate with specific DNA sequences in interphase human cells

18 March 2024

146

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Coiled bodies preferentially associate with U4, U11, and U12 small nuclear RNA genes in interphase HeLa cells but not with U6 and U7 genes

18 March 2024

147

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Association of snRNA genes with coiled bodies is mediated by nascent snRNA transcripts

18 March 2024

148

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Identification of a novel nuclear domain

18 March 2024

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A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein

18 March 2024

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Retinoic acid regulates aberrant nuclear localization of PML-RAR alpha in acute promyelocytic leukemia cells

18 March 2024

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Pondering the promyelocytic leukemia protein (PML) puzzle: possible functions for PML nuclear bodies

18 March 2024

155

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Cellular proteins localized at and interacting within ND10/PML nuclear bodies/PODs suggest functions of a nuclear depot

18 March 2024

156

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Role of promyelocytic leukemia (PML) sumolation in nuclear body formation, 11S proteasome recruitment, and As2O3-induced PML or PML/retinoic acid receptor alpha degradation

18 March 2024

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Localization of nascent RNA and CREB binding protein with the PML-containing nuclear body.

18 March 2024

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Promyelocytic leukemia (PML) nuclear bodies are protein structures that do not accumulate RNA

18 March 2024

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The transcription coactivator CBP is a dynamic component of the promyelocytic leukemia nuclear body

18 March 2024

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CREB-binding protein (CBP)/p300 and RNA polymerase II colocalize in transcriptionally active domains in the nucleus

18 March 2024

161

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Nuclear DNA helicase II is recruited to IFN-alpha-activated transcription sites at PML nuclear bodies.

18 March 2024

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Interaction of SP100 with HP1 proteins: a link between the promyelocytic leukemia-associated nuclear bodies and the chromatin compartment

18 March 2024

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The HP1 protein family: getting a grip on chromatin

18 March 2024

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Metabolic-energy-dependent movement of PML bodies within the mammalian cell nucleus

18 March 2024

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The Polycomb group--no longer an exclusive club?

18 March 2024

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The human polycomb group complex associates with pericentromeric heterochromatin to form a novel nuclear domain

18 March 2024

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Polycomb group gene silencing proteins are concentrated in the perichromatin compartment of the mammalian nucleus

18 March 2024

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The distribution of polycomb-group proteins during cell division and development in Drosophila embryos: impact on models for silencing.

18 March 2024

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Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites

18 March 2024

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Histone methyltransferase activity of a Drosophila Polycomb group repressor complex

18 March 2024

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Role of histone H3 lysine 27 methylation in Polycomb-group silencing

18 March 2024

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Regulation of nuclear localization: a key to a door

18 March 2024

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Regulation of steroid receptor subcellular trafficking

18 March 2024

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Dynamics of gene targeting and chromatin remodelling by nuclear receptors

18 March 2024

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Transcriptional state of the mouse mammary tumor virus promoter can affect topological domain size in vivo

18 March 2024

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Coupled transcription and translation within nuclei of mammalian cells.

18 March 2024

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Nonsense mutations in the alcohol dehydrogenase gene of Drosophila melanogaster correlate with an abnormal 3' end processing of the corresponding pre-mRNA.

18 March 2024

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Precursor RNAs harboring nonsense codons accumulate near the site of transcription

18 March 2024

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Ribosome components are associated with sites of transcription.

18 March 2024

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X-chromosome inactivation: counting, choice and initiation

18 March 2024

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Gene silencing, cell fate and nuclear organisation

18 March 2024

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Transcriptional repression of euchromatic genes by Drosophila heterochromatin protein 1 and histone modifiers

18 March 2024

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Methylation of histone H3 at Lys-9 is an early mark on the X chromosome during X inactivation

18 March 2024

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The language of covalent histone modifications

18 March 2024

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18 March 2024

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34

Barr ML

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Gene action in the X-chromosome of the mouse (Mus musculus L.)

18 March 2024

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A first-generation X-inactivation profile of the human X chromosome

18 March 2024

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Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome.

18 March 2024

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The human XIST gene: analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus

18 March 2024

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Functional analysis of the DXPas34 locus, a 3' regulator of Xist expression

18 March 2024

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Targeted mutagenesis of Tsix leads to nonrandom X inactivation.

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The inactive X chromosome in female mammals is distinguished by a lack of histone H4 acetylation, a cytogenetic marker for gene expression

18 March 2024

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Differentially methylated forms of histone H3 show unique association patterns with inactive human X chromosomes

18 March 2024

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Histone macroH2A1 is concentrated in the inactive X chromosome of female mammals

18 March 2024

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XIST RNA paints the inactive X chromosome at interphase: evidence for a novel RNA involved in nuclear/chromosome structure

18 March 2024

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Three-dimensional reconstruction of painted human interphase chromosomes: active and inactive X chromosome territories have similar volumes but differ in shape and surface structure

18 March 2024

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Perturbation of nuclear architecture by long-distance chromosome interactions.

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Genetic modification of heterochromatic association and nuclear organization in Drosophila.

18 March 2024

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Nonequivalent nuclear location of immunoglobulin alleles in B lymphocytes.

18 March 2024

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Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets.

18 March 2024

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Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitment

18 March 2024

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The lymphoid transcription factor LyF-1 is encoded by specific, alternatively spliced mRNAs derived from the Ikaros gene

18 March 2024

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Segmental determination in Drosophila conferred by hunchback (hb), a repressor of the homeotic gene Ultrabithorax (Ubx)

18 March 2024

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Down-regulation of TDT transcription in CD4(+)CD8(+) thymocytes by Ikaros proteins in direct competition with an Ets activator

18 March 2024

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Binding of Ikaros to the lambda5 promoter silences transcription through a mechanism that does not require heterochromatin formation

18 March 2024

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A functional enhancer suppresses silencing of a transgene and prevents its localization close to centrometric heterochromatin.

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Transcription factor dosage affects changes in higher order chromatin structure associated with activation of a heterochromatic gene

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Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription

18 March 2024

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Expression of alpha- and beta-globin genes occurs within different nuclear domains in haemopoietic cells.

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Nuclear organization and silencing: putting things in their place

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Live imaging of telomeres: yKu and Sir proteins define redundant telomere-anchoring pathways in yeast

18 March 2024

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Perinuclear localization of chromatin facilitates transcriptional silencing

18 March 2024

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The clustering of telomeres and colocalization with Rap1, Sir3, and Sir4 proteins in wild-type Saccharomyces cerevisiae

18 March 2024

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Localization of yeast telomeres to the nuclear periphery is separable from transcriptional repression and telomere stability functions

18 March 2024

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Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres

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Nuclear architecture and spatial positioning help establish transcriptional states of telomeres in yeast.

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Identifiers

1 reference

8 August 2017

1 reference