(Q35166514)

6 August 2017

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title

Signalling from adenosine receptors to mitogen-activated protein kinases (English)

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6 August 2017

Gunnar Schulte

1

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6 August 2017

Bertil B Fredholm

series ordinal

2

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6 August 2017

language of work or name

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1 September 2003

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6 August 2017

number of pages

15

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inferred from page(s)

published in

Cellular Signalling

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6 August 2017

volume

15

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6 August 2017

issue

9

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6 August 2017

page(s)

813-827

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Purinoceptors in the nervous system.

6 August 2017

cites work

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7 January 2021

Purine levels in the intact rat brain. Studies with an implanted perfused hollow fibre

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7 January 2021

Extracellular levels of adenosine and its metabolites in the striatum of awake rats: inhibition of uptake and metabolism

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7 January 2021

Extracellular Adenosine, Inosine, Hypoxanthine, and Xanthine in Relation to Tissue Nucleotides and Purines in Rat Striatum During Transient Ischemia

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7 January 2021

Signal transduction in ischemic preconditioning: the role of kinases and mitochondrial K(ATP) channels

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7 January 2021

Adenosine A2 receptor-mediated excitatory actions on the nervous system

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7 January 2021

Distribution, biochemistry and function of striatal adenosine A2A receptors

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7 January 2021

Functions of neuronal adenosine receptors

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7 January 2021

Adenosine receptor activation and nociception

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7 January 2021

Emerging roles of purinergic signaling in gastrointestinal epithelial secretion and hepatobiliary function.

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7 January 2021

Adenosine, an endogenous anti-inflammatory agent

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7 January 2021

Cloned adenosine A3 receptors: pharmacological properties, species differences and receptor functions

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Mast cell adenosine receptor characteristics and signaling.

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7 January 2021

Adenosine, mast cells and asthma

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Purinergic signaling and vascular cell proliferation and death

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7 January 2021

Modulation of apoptosis by adenosine in the central nervous system: a possible role for the A3 receptor. Pathophysiological significance and therapeutic implications for neurodegenerative disorders

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7 January 2021

Differential effect of adenosine on tumor and normal cell growth: focus on the A3 adenosine receptor

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7 January 2021

The physiological activity of adenine compounds with especial reference to their action upon the mammalian heart

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7 January 2021

Adenosine inhibits the accumulation of cyclic AMP in cultured brain cells

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7 January 2021

Adenosine regulates via two different types of receptors, the accumulation of cyclic AMP in cultured brain cells

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7 January 2021

Subclasses of external adenosine receptors

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7 January 2021

Subclasses of adenosine receptors in the central nervous system: Interaction with caffeine and related methylxanthines

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7 January 2021

Molecular cloning and characterization of an adenosine receptor: the A3 adenosine receptor

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7 January 2021

Astra Award Lecture. Adenosine, adenosine receptors and the actions of caffeine

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7 January 2021

Comparison of the potency of adenosine as an agonist at human adenosine receptors expressed in Chinese hamster ovary cells

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7 January 2021

The adenosine A3 receptor and its ligands

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7 January 2021

Inosine binds to A3 adenosine receptors and stimulates mast cell degranulation

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7 January 2021

Interactions of flavonoids and other phytochemicals with adenosine receptors

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7 January 2021

Genistein, an inhibitor of protein tyrosine kinase, is also a competitive antagonist for P1-purinergic (adenosine) receptor in FRTL-5 thyroid cells

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7 January 2021

Diverse inhibitors of intracellular signalling act as adenosine receptor antagonists

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7 January 2021

Interactions of purified bovine brain A1-adenosine receptors with G-proteins. Reciprocal modulation of agonist and antagonist binding.

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7 January 2021

Differential interaction with and regulation of multiple G-proteins by the rat A3 adenosine receptor

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7 January 2021

Activation of A(3) adenosine receptor induces calcium entry and chloride secretion in A(6) cells.

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7 January 2021

Adenosine A(2A) receptors are colocalized with and activate g(olf) in rat striatum

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7 January 2021

G alpha 15 and G alpha 16 couple a wide variety of receptors to phospholipase C

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7 January 2021

Stimulation of the mitogen-activated protein kinase via the A2A-adenosine receptor in primary human endothelial cells

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7 January 2021

Why are A(2B) receptors low-affinity adenosine receptors? Mutation of Asn273 to Tyr increases affinity of human A(2B) receptor for 2-(1-Hexynyl)adenosine.

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7 January 2021

A2B adenosine and P2Y2 receptors stimulate mitogen-activated protein kinase in human embryonic kidney-293 cells. cross-talk between cyclic AMP and protein kinase c pathways

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7 January 2021

Differential expression of adenosine receptors in human endothelial cells: role of A2B receptors in angiogenic factor regulation

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7 January 2021

Structure and function of adenosine receptors and their genes.

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7 January 2021

Cyclic AMP signaling and gene regulation

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7 January 2021

Structure, function, and control of phosphoinositide-specific phospholipase C

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7 January 2021

Emergent properties of networks of biological signaling pathways

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7 January 2021

Crosstalk and specificity in signalling. Are we crosstalking ourselves into general confusion?

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7 January 2021

https://api.crossref.org/works/10.1016%2FS0898-6568%2803%2900058-5

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7 January 2021

Adenosine receptors: G protein-mediated signalling and the role of accessory proteins.

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7 January 2021

MAP kinase pathways in yeast: for mating and more

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7 January 2021

Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human

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7 January 2021

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7 January 2021

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7 January 2021

Cell signaling by receptor tyrosine kinases

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7 January 2021

The p38 signal transduction pathway: activation and function

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7 January 2021

Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation

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7 January 2021

Connecting signaling and cell cycle progression in growth factor-stimulated cells

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7 January 2021

Growth factor-dependent signaling and cell cycle progression

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7 January 2021

The pathways connecting G protein-coupled receptors to the nucleus through divergent mitogen-activated protein kinase cascades

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7 January 2021

Cell growth control by G protein-coupled receptors: from signal transduction to signal integration

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7 January 2021

G-protein-coupled receptors and signaling networks: emerging paradigms.

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7 January 2021

Protein tyrosine kinase-mediated pathways in G protein-coupled receptor signaling.

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7 January 2021

Regulation of MAP kinase activity by peptide receptor signalling pathway: paradigms of multiplicity

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7 January 2021

Signaling from G-protein-coupled receptors to mitogen-activated protein (MAP)-kinase cascades

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7 January 2021

Regulation of tyrosine kinase cascades by G-protein-coupled receptors.

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7 January 2021

Diversity of G protein-coupled receptor signaling pathways to ERK/MAP kinase

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7 January 2021

Ras-dependent activation of MAP kinase pathway mediated by G-protein beta gamma subunits.

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7 January 2021

Direct evidence that Gi-coupled receptor stimulation of mitogen-activated protein kinase is mediated by G beta gamma activation of p21ras

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7 January 2021

Effect of cellular expression of pleckstrin homology domains on Gi-coupled receptor signaling.

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7 January 2021

Evidence for transduction of mu but not kappa opioid modulation of extracellular signal-regulated kinase activity by G(z) and G(12) proteins

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7 January 2021

Differentiation of PC12 cells in response to a cAMP analogue is accompanied by sustained activation of mitogen-activated protein kinase. Comparison with the effects of insulin, growth factors and phorbol esters

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7 January 2021

Dissociation of cAMP-stimulated Mitogenesis from Activation of the Mitogen-activated Protein Kinase Cascade in Swiss 3T3 Cells

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7 January 2021

Signalling pathways involved in the mitogenic effects of cAMP.

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7 January 2021

Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation

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7 January 2021

Rap1 signalling: adhering to new models

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7 January 2021

Protein kinase A-dependent and -independent signaling pathways contribute to cyclic AMP-stimulated proliferation.

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7 January 2021

Essential role of cAMP-response element-binding protein activation by A2A adenosine receptors in rescuing the nerve growth factor-induced neurite outgrowth impaired by blockage of the MAPK cascade

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7 January 2021

Signaling via A2A adenosine receptor in four PC12 cell clones

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7 January 2021

Regulation of mitogen-activated protein kinase signaling networks by G protein-coupled receptors.

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7 January 2021

Involvement of G-protein betagamma subunits in coupling the adenosine A1 receptor to phospholipase C in transfected CHO cells

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7 January 2021

Human adenosine A1 receptor and P2Y2-purinoceptor-mediated activation of the mitogen-activated protein kinase cascade in transfected CHO cells.

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7 January 2021

Human adenosine A(1), A(2A), A(2B), and A(3) receptors expressed in Chinese hamster ovary cells all mediate the phosphorylation of extracellular-regulated kinase 1/2

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7 January 2021

Regulation of p42/p44 MAPK and p38 MAPK by the adenosine A(1) receptor in DDT(1)MF-2 cells.

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7 January 2021

MAP kinase stimulation by cAMP does not require RAP1 but SRC family kinases

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7 January 2021

Activation of mitogen-activated protein kinase by the A(2A)-adenosine receptor via a rap1-dependent and via a p21(ras)-dependent pathway

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7 January 2021

Stimulatory and inhibitory effects of adenosine A(2A) receptors on nerve growth factor-induced phosphorylation of extracellular regulated kinases 1/2 in PC12 cells

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7 January 2021

Adenosine receptors as mediators of both cell proliferation and cell death of cultured human melanoma cells.

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7 January 2021

Stimulation of human umbilical vein endothelial cell proliferation by A2‐adenosine and β2‐adrenoceptors

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7 January 2021

Biochemical characterization of C3G: an exchange factor that discriminates between Rap1 and Rap2 and is not inhibited by Rap1A(S17N).

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7 January 2021

cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway

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7 January 2021

PKA phosphorylation of Src mediates cAMP's inhibition of cell growth via Rap1.

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7 January 2021

beta 2-adrenergic receptor activates extracellular signal-regulated kinases (ERKs) via the small G protein rap1 and the serine/threonine kinase B-Raf

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7 January 2021

Ras-dependent ERK activation by the human G(s)-coupled serotonin receptors 5-HT4(b) and 5-HT7(a).

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7 January 2021

A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK.

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7 January 2021

Extracellular signal-regulated activation of Rap1 fails to interfere in Ras effector signalling

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7 January 2021

Down-regulation of adenosine A2A receptors upon NGF-induced differentiation of PC12 cells

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7 January 2021

Functional coupling of adenosine A2a receptor to inhibition of the mitogen-activated protein kinase cascade in Chinese hamster ovary cells

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7 January 2021

B-Raf-dependent regulation of the MEK-1/mitogen-activated protein kinase pathway in PC12 cells and regulation by cyclic AMP.

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7 January 2021

Pharmacological characterization of adenosine A2B receptors: studies in human mast cells co-expressing A2A and A2B adenosine receptor subtypes.

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7 January 2021

Adenosine A2b receptors evoke interleukin-8 secretion in human mast cells. An enprofylline-sensitive mechanism with implications for asthma

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7 January 2021

Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP.

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7 January 2021

Mitogenic signaling from P1 and P2 purinergic receptors to mitogen-activated protein kinase in human fetal astrocyte cultures.

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7 January 2021

Regulation of p42/p44 mitogen-activated protein kinase by the human adenosine A3 receptor in transfected CHO cells

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7 January 2021

Signaling pathway from the human adenosine A(3) receptor expressed in Chinese hamster ovary cells to the extracellular signal-regulated kinase 1/2.

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7 January 2021

Glucose-dependent insulinotropic polypeptide activates the Raf-Mek1/2-ERK1/2 module via a cyclic AMP/cAMP-dependent protein kinase/Rap1-mediated pathway.

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7 January 2021

Human dopamine D(3) receptors mediate mitogen-activated protein kinase activation via a phosphatidylinositol 3-kinase and an atypical protein kinase C-dependent mechanism

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7 January 2021

PI 3-kinase gamma and protein kinase C-zeta mediate RAS-independent activation of MAP kinase by a Gi protein-coupled receptor

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7 January 2021

Isoenzyme specificity of bisindolylmaleimides, selective inhibitors of protein kinase C

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7 January 2021

Signal characteristics of G protein-transactivated EGF receptor

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7 January 2021

Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

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7 January 2021

Use of a pharmacophore model for the design of EGF-R tyrosine kinase inhibitors: 4-(phenylamino)pyrazolo[3,4-d]pyrimidines

1 reference

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7 January 2021

Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors

1 reference

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7 January 2021

Platelet-derived-growth-factor stimulation of the p42/p44 mitogen-activated protein kinase pathway in airway smooth muscle: role of pertussis-toxin-sensitive G-proteins, c-Src tyrosine kinases and phosphoinositide 3-kinase

1 reference

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7 January 2021

Activation of the A3 adenosine receptor affects cell cycle progression and cell growth

1 reference

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7 January 2021

The A3 adenosine receptor mediates cell spreading, reorganization of actin cytoskeleton, and distribution of Bcl-XL: studies in human astroglioma cells.

1 reference

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7 January 2021

Adenosine A3 receptor agonists protect HL-60 and U-937 cells from apoptosis induced by A3 antagonists

1 reference

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7 January 2021

Induction of apoptosis in HL-60 human promyelocytic leukemia cells by adenosine A(3) receptor agonists.

1 reference

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7 January 2021

Adenosine A3 receptor agonist-induced neurotoxicity in rat cerebellar granule neurons

1 reference

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7 January 2021

Involvement of mitogen protein kinase cascade in agonist-mediated human A(3) adenosine receptor regulation

1 reference

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7 January 2021

Arresting developments in heptahelical receptor signaling and regulation

1 reference

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7 January 2021

A1 adenosine receptors in human neutrophils: Direct binding and electron microscope visualization

1 reference

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7 January 2021

Involvement of caveolin in ligand-induced recruitment and internalization of A(1) adenosine receptor and adenosine deaminase in an epithelial cell line

1 reference

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7 January 2021

Epidermal growth factor (EGF)-induced up-regulation and agonist- and antagonist-induced desensitization and internalization of A1 adenosine receptors in a pituitary-derived cell line.

1 reference

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7 January 2021

Ligand-Induced Phosphorylation, Clustering, and Desensitization of A1Adenosine Receptors

1 reference

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7 January 2021

Adenosine deaminase and A1 adenosine receptors internalize together following agonist-induced receptor desensitization

1 reference

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7 January 2021

Subtype-specific kinetics of inhibitory adenosine receptor internalization are determined by sensitivity to phosphorylation by G protein-coupled receptor kinases

1 reference

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7 January 2021

Evidence for co-expression and desensitization of A2a and A2b adenosine receptors in NG108-15 cells.

1 reference

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7 January 2021

Rapid agonist-induced desensitization and internalization of the A(2B) adenosine receptor is mediated by a serine residue close to the COOH terminus

1 reference

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7 January 2021

Arrestin specificity for G protein-coupled receptors in human airway smooth muscle

1 reference

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7 January 2021

Arrestin isoforms dictate differential kinetics of A2B adenosine receptor trafficking

1 reference

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7 January 2021

Agonist-Induced Internalization and Recycling of the Human A3 Adenosine Receptors

1 reference

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7 January 2021

7-Nitrobenzofurazan (NBD) derivatives of 5'-N-ethylcarboxamidoadenosine (NECA) as new fluorescent probes for human A(3) adenosine receptors.

1 reference

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7 January 2021

New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades

1 reference

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7 January 2021

RGS-containing RhoGEFs: the missing link between transforming G proteins and Rho?

1 reference

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7 January 2021

D1 dopamine receptor agonists mediate activation of p38 mitogen-activated protein kinase and c-Jun amino-terminal kinase by a protein kinase A-dependent mechanism in SK-N-MC human neuroblastoma cells

1 reference

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7 January 2021

Cyclic AMP-induced neuronal differentiation via activation of p38 mitogen-activated protein kinase

1 reference

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7 January 2021

beta 2-adrenergic receptor-induced p38 MAPK activation is mediated by protein kinase A rather than by Gi or gbeta gamma in adult mouse cardiomyocytes

1 reference

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7 January 2021

Thyroid-stimulating hormone and cyclic AMP activate p38 mitogen-activated protein kinase cascade. Involvement of protein kinase A, rac1, and reactive oxygen species

1 reference

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7 January 2021

Activation of Jun Kinase/Stress-activated Protein Kinase by GTPase-deficient Mutants of Gα12 and Gα13

1 reference

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7 January 2021

Signaling by the G12 class of G proteins

1 reference

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7 January 2021

Regulation of cell proliferation by G proteins

1 reference

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7 January 2021

The role of Rho in G protein-coupled receptor signal transduction

1 reference

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7 January 2021

The A3 adenosine receptor induces cytoskeleton rearrangement in human astrocytoma cells via a specific action on Rho proteins

1 reference

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7 January 2021

A1 adenosine receptor activation inhibits neurite process formation by Rho kinase-mediated pathways

1 reference

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7 January 2021

RhoA inhibition is a key step in pituicyte stellation induced by A(1)-type adenosine receptor activation

1 reference

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7 January 2021

Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3

1 reference

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7 January 2021

Activation of mitogen-activated protein kinases (p38-MAPKs, SAPKs/JNKs and ERKs) by adenosine in the perfused rat heart

1 reference

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7 January 2021

Hyperalgesia, anxiety, and decreased hypoxic neuroprotection in mice lacking the adenosine A1 receptor

1 reference

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7 January 2021

Stimulation of the stress-activated mitogen-activated protein kinase subfamilies in perfused heart. p38/RK mitogen-activated protein kinases and c-Jun N-terminal kinases are activated by ischemia/reperfusion

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2803%2900058-5

7 January 2021

Regulation of mitogen-activated protein kinase cascades in the heart

1 reference

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7 January 2021

Adenosine and preconditioning revisited

1 reference

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7 January 2021

Ischemic preconditioning: from adenosine receptor to KATP channel

1 reference

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7 January 2021

Netrin-1-mediated axon outgrowth and cAMP production requires interaction with adenosine A2b receptor

1 reference

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7 January 2021

Binding of DCC by netrin-1 to mediate axon guidance independent of adenosine A2B receptor activation

1 reference

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7 January 2021

Effector coupling of stably transfected human A3 adenosine receptors in CHO cells

1 reference

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7 January 2021

A1 adenosine receptors expressed in CHO-cells couple to adenylyl cyclase and to phospholipase C.

1 reference

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7 January 2021

Adenosine-activated potassium conductance in cultured striatal neurons

1 reference

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7 January 2021

Calcium-dependent currents in cultured rat dorsal root ganglion neurones are inhibited by an adenosine analogue

1 reference

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7 January 2021

Analysis of adenosine actions on Ca2+ currents and synaptic transmission in cultured rat hippocampal pyramidal neurones

1 reference

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7 January 2021

Differential activation of adenosine receptors decreases N-type but potentiates P-type Ca2+ current in hippocampal CA3 neurons

1 reference

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7 January 2021

Identification of A2a adenosine receptor domains involved in selective coupling to Gs. Analysis of chimeric A1/A2a adenosine receptors

1 reference

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7 January 2021

Molecular cloning and expression of an adenosine A2b receptor from human brain

1 reference

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7 January 2021

Distinct cardioprotective effects of adenosine mediated by differential coupling of receptor subtypes to phospholipases C and D.

1 reference

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7 January 2021

Selective activation of adenosine A3 receptors with N6-(3-chlorobenzyl)-5'-N-methylcarboxamidoadenosine (CB-MECA) provides cardioprotection via KATP channel activation

1 reference

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7 January 2021

A3 adenosine receptors regulate Cl- channels of nonpigmented ciliary epithelial cells

1 reference

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7 January 2021

1 reference

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7 January 2021

Adenosine receptor-mediated changes in cyclic AMP production and DNA synthesis in cultured arterial smooth muscle cells

1 reference

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7 January 2021

Adenosine modulates cell proliferation in human colonic carcinoma. II. Differential behavior of HT29, DLD-1, Caco-2 and SW403 cell lines

1 reference

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7 January 2021

Mitogenic action of adenosine on osteoblast-like cells, MC3T3-E1.

1 reference

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7 January 2021

An adenosine receptor agonist-induced modulation of TSH-dependent cell growth in FRTL-5 thyroid cells mediated by inhibitory G protein, Gi.

1 reference

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7 January 2021

Initiation of a process of differentiation by stable transfection of ob17 preadipocytes with the cDNA of human A1 adenosine receptor

1 reference

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7 January 2021

Inhibition of cell proliferation in the embryonic myocardium by A1 adenosine receptor activation.

1 reference

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7 January 2021

Adenosine receptor activation in quiescent Swiss 3T3 cells. Enhancement of cAMP levels, DNA synthesis and cell division

1 reference

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7 January 2021

Stimulation of astrocyte proliferation by purine and pyrimidine nucleotides and nucleosides

1 reference

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7 January 2021

The effect of catecholamines and adenosine on the induction of morphological alterations and depigmentation of newt iris epithelial cells in vitro

1 reference

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7 January 2021

Modulation of cyclic AMP levels and differentiation by adenosine analogs in mouse erythroleukemia cells

1 reference

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7 January 2021

Extracellular purine nucleosides stimulate cell division and morphogenesis: Pathological and physiological implications

1 reference

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7 January 2021

Smooth muscle cell-derived adenosine inhibits cell growth

1 reference

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7 January 2021

Adenosine stimulation of DNA synthesis in mammary epithelial cells

1 reference

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7 January 2021

Dual effect of adenosine on vascular smooth muscle [(3)H]-thymidine DNA labeling: receptor-mediated modulation of DNA synthesis and inhibition of thymidine uptake

1 reference

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7 January 2021

Adenosine inhibits growth of human aortic smooth muscle cells via A2B receptors

1 reference

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7 January 2021

Adenosine inhibits growth of rat aortic smooth muscle cells. Possible role of A2b receptor

1 reference

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7 January 2021

A(2B) receptors mediate antimitogenesis in vascular smooth muscle cells

1 reference

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7 January 2021

A(2b) receptors mediate the antimitogenic effects of adenosine in cardiac fibroblasts

1 reference

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7 January 2021

A(2B) adenosine receptors stimulate growth of porcine and rat arterial endothelial cells

1 reference

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7 January 2021

Adenosine acts as an inhibitor of lymphoma cell growth: a major role for the A3 adenosine receptor

1 reference

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7 January 2021

Regulation of thymocyte proliferation by endogenous adenosine and adenosine deaminase

1 reference

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7 January 2021

Adenosine inhibits cell division and promotes neurite extension in PC12 cells

1 reference

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7 January 2021

Evidence for negative control of growth by adenosine in the mammalian embryo: induction of Hmx/+ mutant limb outgrowth by adenosine deaminase

1 reference

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7 January 2021

Adenosine and its derivatives control human monocyte differentiation into highly accessory cells versus macrophages

1 reference

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7 January 2021

Adenosine modulates cell growth in human epidermoid carcinoma (A431) cells

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2803%2900058-5

7 January 2021

Purine suppression of proliferation of Sertoli-like TM4 cells in culture

1 reference

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7 January 2021

Adenosine and adenine nucleotides inhibit the autonomous and epidermal growth factor-mediated proliferation of cultured human keratinocytes

1 reference

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7 January 2021

Both adenosine A1- and A2-receptors are required to stimulate microglial proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2803%2900058-5

7 January 2021

Epidermal growth factor protects GH3 cells from adenosine induced growth arrest

1 reference

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7 January 2021

Adenosine stimulates stellation of cultured rat cortical astrocytes

1 reference

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7 January 2021

The role of adenosine receptor engagement in murine fetal thymocyte development.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2803%2900058-5

7 January 2021

10.1016/S0898-6568(03)00058-5

Identifiers

DOI

1 reference

6 August 2017

1 reference