(Q26747063)

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A step-by-step overview of the dynamic process of epitope selection by major histocompatibility complex class II for presentation to helper T cells

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A step-by-step overview of the dynamic process of epitope selection by major histocompatibility complex class II for presentation to helper T cells (English)

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Scheherazade Sadegh-Nasseri

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Scheherazade Sadegh-Nasseri

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2016

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Creative Commons Attribution 4.0 International

9 June 2016

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April 2022 Public Data File from Crossref

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Small molecules that enhance the catalytic efficiency of HLA-DM

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Essential role for cathepsin S in MHC class II-associated invariant chain processing and peptide loading

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7 April 2017

An essential role for HLA-DM in antigen presentation by class II major histocompatibility molecules

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7 April 2017

HLA-DM induces clip dissociation from MHC class II αβ dimers and facilitates peptide loading

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7 April 2017

The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3

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7 April 2017

The complete sequence of the mRNA for the HLA-DR-associated invariant chain reveals a polypeptide with an unusual transmembrane polarity

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7 April 2017

HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides

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7 April 2017

MHC Class II Auto-Antigen Presentation is Unconventional

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7 April 2017

Susceptibility to HLA-DM Protein Is Determined by a Dynamic Conformation of Major Histocompatibility Complex Class II Molecule Bound with Peptide

1 reference

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7 April 2017

Crystal Structure of the HLA-DM–HLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection

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7 April 2017

HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism

1 reference

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7 April 2017

Conformational lability in the class II MHC 310 helix and adjacent extended strand dictate HLA-DM susceptibility and peptide exchange

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7 April 2017

The structure of HLA-DM, the peptide exchange catalyst that loads antigen onto class II MHC molecules during antigen presentation

1 reference

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7 April 2017

Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide

1 reference

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7 April 2017

Exogenous antigens bind MHC class II first, and are processed by cathepsins later

1 reference

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7 April 2017

Interaction of HLA-DR with an acidic face of HLA-DM disrupts sequence-dependent interactions with peptides

1 reference

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7 April 2017

Mice lacking the MHC class II-associated invariant chain

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7 April 2017

A gene in the human major histocompatibility complex class II region controlling the class I antigen presentation pathway

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7 April 2017

Defective antigen processing in GILT-free mice

1 reference

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7 April 2017

Cathepsin L: critical role in Ii degradation and CD4 T cell selection in the thymus

1 reference

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7 April 2017

Invariant chain made in Escherichia coli has an exposed N-terminal segment that blocks antigen binding to HLA-DR1 and a trimeric C-terminal segment that binds empty HLA-DR1

1 reference

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7 April 2017

SYFPEITHI: database for MHC ligands and peptide motifs

1 reference

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7 April 2017

The Dendritic Cell Major Histocompatibility Complex II (MHC II) Peptidome Derives from a Variety of Processing Pathways and Includes Peptides with a Broad Spectrum of HLA-DM Sensitivity

1 reference

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28 September 2017

The Thermodynamic Mechanism of Peptide-MHC Class II Complex Formation Is a Determinant of Susceptibility to HLA-DM.

1 reference

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28 September 2017

Determinants of immunodominance for CD4 T cells

1 reference

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28 September 2017

Divergent paths for the selection of immunodominant epitopes from distinct antigenic sources

1 reference

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28 September 2017

Proteases: essential actors in processing antigens and intracellular toll-like receptors.

1 reference

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28 September 2017

HLA-DO and Its Role in MHC Class II Antigen Presentation.

1 reference

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28 September 2017

HLA-DO as the optimizer of epitope selection for MHC class II antigen presentation

1 reference

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28 September 2017

Pathways of antigen processing

1 reference

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28 September 2017

Expanding roles for GILT in immunity

1 reference

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28 September 2017

HLA-DM constrains epitope selection in the human CD4 T cell response to vaccinia virus by favoring the presentation of peptides with longer HLA-DM-mediated half-lives

1 reference

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28 September 2017

Peptidylarginine deiminase 2, 3 and 4 have distinct specificities against cellular substrates: novel insights into autoantigen selection in rheumatoid arthritis

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28 September 2017

Disulfide reduction in the endocytic pathway: immunological functions of gamma-interferon-inducible lysosomal thiol reductase

1 reference

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28 September 2017

HLA-DM captures partially empty HLA-DR molecules for catalyzed removal of peptide

1 reference

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28 September 2017

Routes to manipulate MHC class II antigen presentation

1 reference

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28 September 2017

A reductionist cell-free major histocompatibility complex class II antigen processing system identifies immunodominant epitopes.

1 reference

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28 September 2017

An expanded self-antigen peptidome is carried by the human lymph as compared to the plasma.

1 reference

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28 September 2017

Unique autoreactive T cells recognize insulin peptides generated within the islets of Langerhans in autoimmune diabetes

1 reference

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28 September 2017

Conformational heterogeneity of MHC class II induced upon binding to different peptides is a key regulator in antigen presentation and epitope selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 September 2017

Heterogeneity and plasticity of T helper cells

1 reference

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28 September 2017

Cutting edge: HLA-DM functions through a mechanism that does not require specific conserved hydrogen bonds in class II MHC-peptide complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 September 2017

HLA-DM mediates peptide exchange by interacting transiently and repeatedly with HLA-DR1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 September 2017

HLA-DM mediates epitope selection by a "compare-exchange" mechanism when a potential peptide pool is available

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 September 2017

The convergent roles of tapasin and HLA-DM in antigen presentation.

1 reference

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28 September 2017

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28 September 2017

HLA-DM targets the hydrogen bond between the histidine at position beta81 and peptide to dissociate HLA-DR-peptide complexes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 September 2017

Endosomal proteases in antigen presentation

1 reference

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28 September 2017

The lysosomal cysteine proteases in MHC class II antigen presentation

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28 September 2017

Identification of Plasmodium falciparum antigens by antigenic analysis of genomic and proteomic data

1 reference

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28 September 2017

Lysosomal cysteine proteases regulate antigen presentation

1 reference

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28 September 2017

APCs present A beta(k)-derived peptides that are autoantigenic to type B T cells.

1 reference

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28 September 2017

Formation of two peptide/MHC II isomers is catalyzed differentially by HLA-DM.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 September 2017

The kinetic basis of peptide exchange catalysis by HLA-DM

1 reference

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28 September 2017

Relaxed DM requirements during class II peptide loading and CD4+ T cell maturation in BALB/c mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 September 2017

Identification and modulation of a naturally processed T cell epitope from the diabetes-associated autoantigen human glutamic acid decarboxylase 65 (hGAD65).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 September 2017

HLA-DM recognizes the flexible conformation of major histocompatibility complex class II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 September 2017

Proteolysis in MHC class II antigen presentation: who's in charge?

1 reference

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28 September 2017

Extracellular antigen processing and presentation by immature dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 September 2017

Cathepsin S controls the trafficking and maturation of MHC class II molecules in dendritic cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 September 2017

Cathepsin S activity regulates antigen presentation and immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 September 2017

HLA-DM interactions with intermediates in HLA-DR maturation and a role for HLA-DM in stabilizing empty HLA-DR molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 September 2017

Evidence that binding site occupancy is necessary and sufficient for effective major histocompatibility complex (MHC) class II transport through the secretory pathway redefines the primary function of class II-associated invariant chain peptides (CL

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 September 2017

Invariant chain structure and MHC class II function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 September 2017

A mutant human histocompatibility leukocyte antigen DR molecule associated with invariant chain peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 September 2017

Isolation and characterization of the intracellular MHC class II compartment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 September 2017

Dominance and crypticity of T cell antigenic determinants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 September 2017

Direct observation of disordered regions in the major histocompatibility complex class II-associated invariant chain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 September 2017

Cell surface expression of class II histocompatibility antigens occurs in the absence of the invariant chain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 September 2017

Refolding and reassembly of separate alpha and beta chains of class II molecules of the major histocompatibility complex leads to increased peptide-binding capacity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 September 2017

Regulation of antigen presentation by acidic pH.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 September 2017

Peptide binding to HLA-DR1: a peptide with most residues substituted to alanine retains MHC binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 September 2017

Kinetics of antigenic peptide binding to the class II major histocompatibility molecule I-Ad

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 September 2017

A gene required for class II-restricted antigen presentation maps to the major histocompatibility complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 September 2017

HLA-A2.1-associated peptides from a mutant cell line: a second pathway of antigen presentation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 September 2017

How MHC class II molecules work: peptide-dependent completion of protein folding.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 September 2017

Two-gene control of the expression of a murine Ia antigen

1 reference

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28 September 2017

MHC class II function preserved by low-affinity peptide interactions preceding stable binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 September 2017

Major histocompatibility complex class II molecules induce the formation of endocytic MIIC-like structures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 September 2017

Accumulation of HLA-DM, a regulator of antigen presentation, in MHC class II compartments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 September 2017

Assembly and intracellular transport of HLA-DM and correction of the class II antigen-processing defect in T2 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 September 2017

Mediation by HLA-DM of dissociation of peptides from HLA-DR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 September 2017

A Peptide/MHCII conformer generated in the presence of exchange peptide is substrate for HLA-DM editing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

31 May 2018

The lymph as a pool of self-antigens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

31 May 2018

Whole proteomes as internal standards in quantitative proteomics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

31 May 2018

Determinants of the peptide-induced conformational change in the human class II major histocompatibility complex protein HLA-DR1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

31 May 2018

Sodium dodecyl sulfate stability of HLA-DR1 complexes correlates with burial of hydrophobic residues in pocket 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

31 May 2018

Selection of the MHC class II-associated peptide repertoire by HLA-DM.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

31 May 2018

Interaction of peptide antigens and class II major histocompatibility complex antigens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

31 May 2018

A kinetic intermediate in the reaction of an antigenic peptide and I-Ek

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

31 May 2018

T cell recognition of fibrinogen. A determinant on the A alpha-chain does not require processing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

31 May 2018

Invariant chain distinguishes between the exogenous and endogenous antigen presentation pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

31 May 2018

Invariant chain association with HLA-DR molecules inhibits immunogenic peptide binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

31 May 2018

The biosynthetic pathway of MHC class II but not class I molecules intersects the endocytic route

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

31 May 2018

Defective processing and presentation of exogenous antigens in mutants with normal HLA class II genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

31 May 2018

MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

31 May 2018

Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

31 May 2018

Invariant chain peptides in most HLA-DR molecules of an antigen-processing mutant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

31 May 2018

The human class II MHC protein HLA-DR1 assembles as empty alpha beta heterodimers in the absence of antigenic peptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

31 May 2018

Inhibition of endosomal proteolytic activity by leupeptin blocks surface expression of MHC class II molecules and their conversion to SDS resistance alpha beta heterodimers in endosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

31 May 2018

Sibling rivalry: competition between MHC class II family members inhibits immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 November 2018

Short peptide sequences mimic HLA-DM functions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 November 2018

Enhanced catalytic action of HLA-DM on the exchange of peptides lacking backbone hydrogen bonds between their N-terminal region and the MHC class II alpha-chain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 November 2018

Activation of lysosomal function during dendritic cell maturation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 November 2018

Specific role for cathepsin S in the generation of antigenic peptides in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 November 2018

Allocation of helper T-cell epitope immunodominance according to three-dimensional structure in the human immunodeficiency virus type I envelope glycoprotein gp120.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 November 2018

Formation of a highly peptide-receptive state of class II MHC.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 November 2018

Structure of a trimeric domain of the MHC class II-associated chaperonin and targeting protein Ii.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 November 2018

Antigen processing and class II MHC peptide-loading compartments in human B-lymphoblastoid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 November 2018

Structural intermediates in the reactions of antigenic peptides with MHC molecules.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 November 2018

Intracellular transport of class II MHC molecules directed by invariant chain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4902097

28 November 2018

A role for peptide in determining MHC class II structure

1 reference

https://pubmed.ncbi.nlm.nih.gov/27347387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transient accumulation of new class II MHC molecules in a novel endocytic compartment in B lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/27347387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Capacity of intact proteins to bind to MHC class II molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/27347387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intact proteins can bind to class II histocompatibility molecules with high affinity

1 reference

https://pubmed.ncbi.nlm.nih.gov/27347387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stable peptide binding to MHC class II molecule is rapid and is determined by a receptive conformation shaped by prior association with low affinity peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/27347387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of type B T cells after protein immunization reveals novel pathways of in vivo presentation of peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/27347387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting edge: H-2DM is responsible for the large differences in presentation among peptides selected by I-Ak during antigen processing

1 reference

https://pubmed.ncbi.nlm.nih.gov/27347387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

One of two unstructured domains of Ii becomes ordered in complexes with MHC class II molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/27347387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired invariant chain degradation and antigen presentation and diminished collagen-induced arthritis in cathepsin S null mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/27347387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peptide binding inhibits protein aggregation of invariant-chain free class II dimers and promotes surface expression of occupied molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/27347387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extensive trafficking of MHC class II-invariant chain complexes in the endocytic pathway and appearance of peptide-loaded class II in multiple compartments

1 reference

https://pubmed.ncbi.nlm.nih.gov/27347387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The phenotype of H-2M-deficient mice is dependent on the MHC class II molecules expressed

1 reference

https://pubmed.ncbi.nlm.nih.gov/27347387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Large protein fragments as substrates for endocytic antigen capture by MHC class II molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/27347387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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