(Q36781670)

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Tetraploid cells produced by absence of substrate adhesion during cytokinesis are limited in their proliferation and enter senescence after DNA replication

scientific article published on 22 December 2015

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16 August 2017

Tetraploid cells produced by absence of substrate adhesion during cytokinesis are limited in their proliferation and enter senescence after DNA replication (English)

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Europe PubMed Central

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16 August 2017

Marco De Santis Puzzonia

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26693937%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Laetitia Gonzalez

2

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9 June 2020

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Sonia Ascenzi

3

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9 June 2020

Enrico Cundari

4

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9 June 2020

Francesca Degrassi

5

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9 June 2020

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22 December 2015

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16 August 2017

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9 June 2020

15

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9 June 2020

2

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9 June 2020

274-282

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9 June 2020

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11 June 2022

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Matrix compliance and the regulation of cytokinesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4825921

29 September 2017

HIPK2 deficiency causes chromosomal instability by cytokinesis failure and increases tumorigenicity

1 reference

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29 September 2017

Failure of cell cleavage induces senescence in tetraploid primary cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4825921

29 September 2017

Cytokinesis failure triggers hippo tumor suppressor pathway activation.

1 reference

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29 September 2017

Tolerance of whole-genome doubling propagates chromosomal instability and accelerates cancer genome evolution.

1 reference

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29 September 2017

Characterization and preclinical development of LY2603618: a selective and potent Chk1 inhibitor

1 reference

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29 September 2017

Abnormal mitosis triggers p53-dependent cell cycle arrest in human tetraploid cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4825921

29 September 2017

2n or not 2n: Aneuploidy, polyploidy and chromosomal instability in primary and tumor cells

1 reference

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29 September 2017

Telomere-driven tetraploidization occurs in human cells undergoing crisis and promotes transformation of mouse cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4825921

29 September 2017

Cytokinesis failure due to derailed integrin traffic induces aneuploidy and oncogenic transformation in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4825921

29 September 2017

The causes and consequences of polyploidy in normal development and cancer

1 reference

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29 September 2017

Repeated cleavage failure does not establish centrosome amplification in untransformed human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4825921

29 September 2017

Hallmarks of Cancer: The Next Generation

1 reference

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29 September 2017

The requirement of p53 for maintaining chromosomal stability during tetraploidization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4825921

29 September 2017

Cell migration regulates the kinetics of cytokinesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4825921

29 September 2017

Prolonged Prometaphase Blocks Daughter Cell Proliferation Despite Normal Completion of Mitosis

1 reference

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29 September 2017

The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis

1 reference

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29 September 2017

The consequences of tetraploidy and aneuploidy

1 reference

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29 September 2017

Integrin trafficking regulated by Rab21 is necessary for cytokinesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4825921

29 September 2017

Mechanism of G1-like arrest by low concentrations of paclitaxel: next cell cycle p53-dependent arrest with sub G1 DNA content mediated by prolonged mitosis

1 reference

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29 September 2017

Anchorage-independent cytokinesis as part of oncogenic transformation?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4825921

29 September 2017

Oncogenic H-Ras V12 promotes anchorage-independent cytokinesis in human fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4825921

29 September 2017

Limiting the proliferation of polyploid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4825921

29 September 2017

Cellular senescence in cancer and aging

1 reference

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29 September 2017

Perturbing integrin function inhibits microtubule growth from centrosomes, spindle assembly, and cytokinesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4825921

29 September 2017

Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells

1 reference

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29 September 2017

Mammalian cells lack checkpoints for tetraploidy, aberrant centrosome number, and cytokinesis failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4825921

29 September 2017

Cell cycle progression after cleavage failure: mammalian somatic cells do not possess a "tetraploidy checkpoint".

1 reference

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29 September 2017

p53 displacement from centrosomes and p53-mediated G1 arrest following transient inhibition of the mitotic spindle.

1 reference

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29 September 2017

Tetraploid state induces p53-dependent arrest of nontransformed mammalian cells in G1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4825921

29 September 2017

Regulation of the G2/M transition by p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4825921

29 September 2017

The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites

1 reference

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29 September 2017

The complexity of p53 modulation: emerging patterns from divergent signals

1 reference

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29 September 2017

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

1 reference

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29 September 2017

Characterization of the p53-dependent postmitotic checkpoint following spindle disruption

1 reference

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29 September 2017

Topoisomerase II inhibition in mitosis produces numerical and structural chromosomal aberrations in human fibroblasts.

1 reference

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29 September 2017

Multinucleation and inhibition of cytokinesis in suspended cells: reversal upon reattachment to a substrate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4825921

27 June 2018

A virus causes cancer by inducing massive chromosomal instability through cell fusion

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5 September 2018

G2 damage checkpoints: what is the turn-on?

1 reference

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5 September 2018

p53-independent apoptosis and p53-dependent block of DNA rereplication following mitotic spindle inhibition in human cells.

1 reference

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5 September 2018

Identifiers

10.1080/15384101.2015.1127469

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26693937%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

PMC publication ID

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9 June 2020

PubMed publication ID

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9 June 2020

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