(Q35110418)

6 August 2017

title

Dual blockade of EGFR and c-Met abrogates redundant signaling and proliferation in head and neck carcinoma cells (English)

1 reference

6 August 2017

main subject

head and neck carcinoma

1 reference

inferred from title

author

Jennifer Rubin Grandis

5

object named as

Jennifer R Grandis

1 reference

6 August 2017

Hai Xu

1

1 reference

6 August 2017

Laura P Stabile

2

1 reference

6 August 2017

Christopher T Gubish

3

1 reference

6 August 2017

William E Gooding

4

1 reference

6 August 2017

Jill M Siegfried

6

1 reference

6 August 2017

language of work or name

English

0 references

publication date

27 May 2011

1 reference

6 August 2017

published in

Clinical Cancer Research

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6 August 2017

volume

17

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6 August 2017

issue

13

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6 August 2017

page(s)

4425-4438

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describes a project that uses

6 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3138116/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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New strategies in head and neck cancer: understanding resistance to epidermal growth factor receptor inhibitors

9 July 2018

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9 July 2018

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Epidermal growth factor receptor regulates MET levels and invasiveness through hypoxia-inducible factor-1alpha in non-small cell lung cancer cells

9 July 2018

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Acquired resistance of non-small cell lung cancer cells to MET kinase inhibition is mediated by a switch to epidermal growth factor receptor dependency

9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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HGF and c-Met participate in paracrine tumorigenic pathways in head and neck squamous cell cancer

9 July 2018

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9 July 2018

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9 July 2018

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HER kinase activation confers resistance to MET tyrosine kinase inhibition in MET oncogene-addicted gastric cancer cells

9 July 2018

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Therapeutic targeting of human hepatocyte growth factor with a single neutralizing monoclonal antibody reduces lung tumorigenesis

9 July 2018

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Drug development of MET inhibitors: targeting oncogene addiction and expedience

9 July 2018

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Signaling networks assembled by oncogenic EGFR and c-Met

9 July 2018

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Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies

9 July 2018

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Epidermal growth factor receptor copy number alterations correlate with poor clinical outcome in patients with head and neck squamous cancer

9 July 2018

1 reference

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An orally available small-molecule inhibitor of c-Met, PF-2341066, exhibits cytoreductive antitumor efficacy through antiproliferative and antiangiogenic mechanisms

9 July 2018

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MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling

9 July 2018

1 reference

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Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.

9 July 2018

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The epidemiology and risk factors of head and neck cancer: a focus on human papillomavirus

9 July 2018

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Cross-talk between G protein-coupled receptor and epidermal growth factor receptor signaling pathways contributes to growth and invasion of head and neck squamous cell carcinoma

9 July 2018

1 reference

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ErbB receptors and epithelial-cadherin-catenin complex in human carcinomas

9 July 2018

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Epidermal growth factor receptor biology in head and neck cancer

9 July 2018

1 reference

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Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer

9 July 2018

1 reference

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Critical update and emerging trends in epidermal growth factor receptor targeting in cancer

9 July 2018

1 reference

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c-Met signalling: spatio-temporal decisions

9 July 2018

1 reference

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HGF/SF-Met signaling in tumor progression

9 July 2018

1 reference

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Multicenter phase II study of erlotinib, an oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with recurrent or metastatic squamous cell cancer of the head and neck

9 July 2018

1 reference

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Met, metastasis, motility and more

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138116

Src kinases mediate STAT growth pathways in squamous cell carcinoma of the head and neck

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138116

Epidermal growth factor receptor: mechanisms of activation and signalling.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138116

Scatter-factor and semaphorin receptors: cell signalling for invasive growth

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138116

Untangling the ErbB signalling network

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138116

Cross-talk between epidermal growth factor receptor and c-Met signal pathways in transformed cells

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138116

Activation of both MAP kinase and phosphatidylinositide 3-kinase by Ras is required for hepatocyte growth factor/scatter factor-induced adherens junction disassembly

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138116

Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138116

Inhibition of epidermal growth factor receptor gene expression and function decreases proliferation of head and neck squamous carcinoma but not normal mucosal epithelial cells

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138116

Epidermal growth factor receptor expression by human squamous cell carcinomas of the head and neck, cell lines and xenografts

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138116

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138116

MET kinase inhibitor SGX523 synergizes with epidermal growth factor receptor inhibitor erlotinib in a hepatocyte growth factor-dependent fashion to suppress carcinoma growth

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138116

Transgenic mice overexpressing hepatocyte growth factor in the airways show increased susceptibility to lung cancer

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138116

C-Met overexpression in node-positive breast cancer identifies patients with poor clinical outcome independent of Her2/neu

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138116

c-MET expression level in primary colon cancer: a predictor of tumor invasion and lymph node metastases.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138116

Open-Label, Uncontrolled, Multicenter Phase II Study to Evaluate the Efficacy and Toxicity of Cetuximab As a Single Agent in Patients With Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck Who Failed to Respond to Platinum-Base

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138116

Aberrant EGFR and chromosome 7 associate with outcome in laryngeal cancer

16 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21622718

12 December 2020

inferred from PubMed ID database lookup

Detection of EGFR- and HER2-activating mutations in squamous cell carcinoma involving the head and neck

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21622718

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1158/1078-0432.CCR-10-3339

1 reference

6 August 2017

1 reference

6 August 2017

1 reference