(Q339499)

http://www.ebi.ac.uk/interpro/protein/P00748

Kringle-like fold

1 reference

http://www.ebi.ac.uk/interpro/protein/P00748

Peptidase S1, PA clan

1 reference

http://www.ebi.ac.uk/interpro/protein/P00748

Fibronectin type II domain superfamily

1 reference

http://www.ebi.ac.uk/interpro/protein/P00748

Kringle superfamily

1 reference

http://www.ebi.ac.uk/interpro/protein/P00748

Kringle domain, protein family

1 reference

Serine proteases, trypsin domain, protein family

1 reference

Fibronectin type II domain, protein family

1 reference

EGF-like calcium-binding domain, protein family

1 reference

Kringle, conserved site, protein family

1 reference

Fibronectin, type I, protein family

1 reference

EGF-like domain, protein family

1 reference

Serine proteases, trypsin family, histidine active site, protein family

1 reference

EGF-like, conserved site, protein family

1 reference

Serine proteases, trypsin family, serine active site, protein family

1 reference

misfolded protein binding

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

Misfolded proteins activate factor XII in humans, leading to kallikrein formation without initiating coagulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

2 references

8 April 2019

Histidine-rich glycoprotein binds factor XIIa with high affinity and inhibits contact-initiated coagulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

8 April 2019

Identification of the zinc-dependent endothelial cell binding protein for high molecular weight kininogen and factor XII: identity with the receptor that binds to the globular "heads" of C1q (gC1q-R)

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

serine-type peptidase activity

IPI

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

serine-type endopeptidase activity

4 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00748&geneProductId=UniProtKB:P00748

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00748&geneProductId=UniProtKB:P00748

26 September 2017

Misfolded proteins activate factor XII in humans, leading to kallikrein formation without initiating coagulation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00748&geneProductId=UniProtKB:P00748

26 September 2017

Isolation and properties of an abnormal Hageman factor (Factor XII) molecule in a cross-reacting material-positive hageman trait plasma

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00748&geneProductId=UniProtKB:P00748

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

serine-type endopeptidase activity

5 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00748&geneProductId=UniProtKB:P00748

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00748&geneProductId=UniProtKB:P00748

1 January 2018

Misfolded proteins activate factor XII in humans, leading to kallikrein formation without initiating coagulation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00748&geneProductId=UniProtKB:P00748

1 January 2018

Isolation and properties of an abnormal Hageman factor (Factor XII) molecule in a cross-reacting material-positive hageman trait plasma

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00748&geneProductId=UniProtKB:P00748

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00748&geneProductId=UniProtKB:P00748

serine-type endopeptidase activity

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

8 April 2019

Isolation and properties of an abnormal Hageman factor (Factor XII) molecule in a cross-reacting material-positive hageman trait plasma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

8 April 2019

Misfolded proteins activate factor XII in humans, leading to kallikrein formation without initiating coagulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

extracellular exosome

3 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00748&geneProductId=UniProtKB:P00748

26 September 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00748&geneProductId=UniProtKB:P00748

26 September 2017

Isolation and properties of an abnormal Hageman factor (Factor XII) molecule in a cross-reacting material-positive hageman trait plasma

http://www.ebi.ac.uk/QuickGO/annotations?protein=P00748&geneProductId=UniProtKB:P00748

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

8 April 2019

Isolation and properties of an abnormal Hageman factor (Factor XII) molecule in a cross-reacting material-positive hageman trait plasma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

rough endoplasmic reticulum

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

extracellular exosome

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

collagen-containing extracellular matrix

HDA

1 reference

8 April 2019

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

response to misfolded protein

1 reference

8 April 2019

Misfolded proteins activate factor XII in humans, leading to kallikrein formation without initiating coagulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

positive regulation of plasminogen activation

1 reference

8 April 2019

Hageman-factor-dependent fibrinolysis: generation of fibrinolytic activity by the interaction of human activated factor XI and plasminogen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

3 references

8 April 2019

Isolation and properties of an abnormal Hageman factor (Factor XII) molecule in a cross-reacting material-positive hageman trait plasma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

8 April 2019

Hageman-factor-dependent fibrinolysis: generation of fibrinolytic activity by the interaction of human activated factor XI and plasminogen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

8 April 2019

Misfolded proteins activate factor XII in humans, leading to kallikrein formation without initiating coagulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

1 reference

8 April 2019

Misfolded proteins activate factor XII in humans, leading to kallikrein formation without initiating coagulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

Misfolded proteins activate factor XII in humans, leading to kallikrein formation without initiating coagulation

protein autoprocessing

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

positive regulation of blood coagulation

1 reference

8 April 2019

Isolation and properties of an abnormal Hageman factor (Factor XII) molecule in a cross-reacting material-positive hageman trait plasma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

positive regulation of fibrinolysis

1 reference

8 April 2019

Hageman-factor-dependent fibrinolysis: generation of fibrinolytic activity by the interaction of human activated factor XI and plasminogen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

Coagulation factor XII (Hageman factor) Washington D.C.: inactive factor XIIa results from Cys-571----Ser substitution

innate immune response

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

regulation of blood coagulation

TAS

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

plasma kallikrein-kinin cascade

Misfolded proteins activate factor XII in humans, leading to kallikrein formation without initiating coagulation

2 references

Factor XII activation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00748

http://purl.uniprot.org/uniprot/P00748

Gene Atlas image

PBB GE F12 205774 at fs.png
732 × 530; 10 KB

0 references

exact match

1 reference

serine proteases, trypsin family, histidine active site

Identifiers.org

has part(s)

1 reference

http://www.ebi.ac.uk/interpro/protein/P00748

EGF-like, conserved site

1 reference

http://www.ebi.ac.uk/interpro/protein/P00748

fibronectin, type I

1 reference

http://www.ebi.ac.uk/interpro/protein/P00748

kringle

1 reference

http://www.ebi.ac.uk/interpro/protein/P00748

serine proteases, trypsin domain

1 reference

http://www.ebi.ac.uk/interpro/protein/P00748

fibronectin type II domain

1 reference

http://www.ebi.ac.uk/interpro/protein/P00748

EGF-like calcium-binding domain

1 reference

http://www.ebi.ac.uk/interpro/protein/P00748

EGF-like domain

1 reference

http://www.ebi.ac.uk/interpro/protein/P00748

kringle, conserved site

1 reference

http://www.ebi.ac.uk/interpro/protein/P00748

Serine proteases, trypsin family, serine active site

1 reference

http://www.ebi.ac.uk/interpro/protein/P00748

Identifiers

MeSH descriptor ID

D005174

subject named as

Factor XII

0 references

0 references

0 references

0 references

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

28 October 2013

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

inferred by common MeSH mappings on source and on Wikidata

1 reference