(Q27852966)

13 November 2016

title

Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition (English)

1 reference

PubMed

PubMed publication ID

13 November 2016

0 references

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69

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Christof von Kalle

42

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Roland Eils

73

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Andreas von Deimling

47

Andreas von Deimling

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Christel Herold-Mende

44

Christel Herold-Mende

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Jüri Reimand

24

Jüri Reimand

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Huriye Seker-Cin

18

Huriye Seker-Cin

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Peter van Sluis

34

Peter van Sluis

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Andreas Unterberg

43

Andreas Unterberg

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Cynthia Cowdrey

56

Cynthia Cowdrey

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Ulrich Schüller

71

Ulrich Schüller

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Martin Hasselblatt

51

Martin Hasselblatt

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Nada Jabado

54

Nada Jabado

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Tobias Rausch

Tobias Rausch

22

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Volker Hovestadt

Volker Hovestadt

6

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Dominik Sturm

Dominik Sturm

14

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Till Milde

Till Milde

11

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Trevor J Pugh

Trevor J Pugh

5

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Marc Remke

Marc Remke

10

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Rogier Versteeg

Rogier Versteeg

37

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Jan Koster

Jan Koster

36

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Rosario M. Piro

Rosario M Piro

7

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Martin McCabe

Martin G McCabe

63

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Mark W. Kieran

Mark W Kieran

65

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Gary D. Bader

Gary D Bader

62

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Stefan M. Pfister

Stefan M Pfister

76

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Olivier Delattre

Olivier Delattre

61

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Franck Bourdeaut

12

Franck Bourdeaut

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Jörg Felsberg

49

Jörg Felsberg

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Peter Lichter

75

Peter Lichter

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Marcel Kool

1

Marcel Kool

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Paul A Northcott

4

Paul A Northcott

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Andrey Korshunov

72

Andrey Korshunov

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Rameen Beroukhim

32

Rameen Beroukhim

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David T. W. Jones

2

David T W Jones

1 reference

ORCID Public Data File 2021

François Doz

60

Francois Doz

1 reference

ORCID Public Data File 2021

Robert J Wechsler-Reya

74

Robert J Wechsler-Reya

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Scott L Pomeroy

67

Scott L Pomeroy

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Yoon-Jae Cho

66

Yoon-Jae Cho

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David J. H. Shih

23

David Shih

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Andreas E Kulozik

46

Andreas E Kulozik

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Michael D. Taylor

70

Michael D Taylor

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Jan Korbel

59

Jan O Korbel

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John R Crawford

52

John R Crawford

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Natalie Jäger

3

Natalie Jäger

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Marina Ryzhova

13

Marina Ryzhova

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Elke Pfaff

15

Elke Pfaff

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Laura Sieber

25

Laura Sieber

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Sonja Hutter

17

Sonja Hutter

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Cynthia C Bartholomae

41

Cynthia C Bartholomae

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Chris Lawerenz

40

Chris Lawerenz

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Richard Volckmann

35

Richard Volckmann

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Olaf Witt

68

Olaf Witt

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Wolfram Scheurlen

48

Wolfram Scheurlen

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Marc Zapatka

30

Marc Zapatka

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Sebastian Stark

16

Sebastian Stark

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Linda Linke

27

Linda Linke

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Pascal Johann

19

Pascal Johann

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Arie Perry

55

Arie Perry

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Silvia Hofer

45

Silvia Hofer

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Christin Schmidt

21

Christin Schmidt

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Guillaume Bergthold

33

Guillaume Bergthold

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Gelareh Zadeh

58

Gelareh Zadeh

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author name string

L Adriana Esparza

8

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Shirley L Markant

9

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Sebastian Bender

20

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Andrea Wittmann

26

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Hendrik Witt

28

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Ursula D Weber

29

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Rainer König

31

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Sabine Schmidt

38

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Stephan Wolf

39

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Gerald A Grant

53

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Sydney Croul

57

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V Peter Collins

Itraconazole and arsenic trioxide inhibit Hedgehog pathway activation and tumor growth associated with acquired resistance to smoothened antagonists

64

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publication date

17 March 2014

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published in

Cancer Cell

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volume

25

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issue

3

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page(s)

393-405

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20 March 2017

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Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathway

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Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma.

20 March 2017

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20 March 2017

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Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations

7 April 2017

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TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma

24 May 2017

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Subgroup-specific prognostic implications of TP53 mutation in medulloblastoma

29 September 2017

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TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

29 September 2017

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Medulloblastoma with excessive nodularity: radiographic features and pathologic correlate

29 September 2017

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Novel mutations target distinct subgroups of medulloblastoma.

29 September 2017

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Hedgehog pathway as a drug target: Smoothened inhibitors in development

29 September 2017

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Global gene expression profiling confirms the molecular fidelity of primary tumor-based orthotopic xenograft mouse models of medulloblastoma

29 September 2017

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Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas

29 September 2017

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Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations

29 September 2017

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MYC family amplification and clinical risk-factors interact to predict an extremely poor prognosis in childhood medulloblastoma

29 September 2017

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Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct

29 September 2017

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29 September 2017

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Medulloblastoma: clinicopathological correlates of SHH, WNT, and non-SHH/WNT molecular subgroups

29 September 2017

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Small molecule inhibition of GDC-0449 refractory smoothened mutants and downstream mechanisms of drug resistance

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Common strategy for adult and pediatric medulloblastoma: a multicenter series of 253 adults

29 September 2017

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29 September 2017

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High frequency of germline SUFU mutations in children with desmoplastic/nodular medulloblastoma younger than 3 years of age.

2 June 2018

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Interfering with resistance to smoothened antagonists by inhibition of the PI3K pathway in medulloblastoma.

2 June 2018

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2 June 2018

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Distribution of TERT promoter mutations in pediatric and adult tumors of the nervous system

2 June 2018

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Sonic hedgehog-associated medulloblastoma arising from the cochlear nuclei of the brainstem

27 November 2018

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27 November 2018

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Not lost in space: trafficking in the hedgehog signaling pathway.

27 November 2018

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Direct orthotopic transplantation of fresh surgical specimen preserves CD133+ tumor cells in clinically relevant mouse models of medulloblastoma and glioma.

27 November 2018

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Transient inhibition of the Hedgehog pathway in young mice causes permanent defects in bone structure

27 November 2018

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27 November 2018

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Survival of adults treated for medulloblastoma using paediatric protocols.

27 November 2018

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10.1016/J.CCR.2014.02.004

27 November 2018

Identifiers

DOI

1 reference

release_qc25q7h6kvfk5ko63vw4g7qley

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/qc25q7h6kvfk5ko63vw4g7qley

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

1 reference

PubMed publication ID

24651015

1 reference