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| Verfasst von: | Schwaab, Juliana [VerfasserIn]  |
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| | Brockow, Knut [VerfasserIn] |
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| | Riffel, Philipp [VerfasserIn] |
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| | Lübke, Johannes [VerfasserIn] |
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| | Naumann, Nicole [VerfasserIn] |
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| | Jawhar, Mohamad [VerfasserIn] |
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| | Reiter, Lukas [VerfasserIn] |
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| | Fabarius, Alice [VerfasserIn] |
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| | Metzgeroth, Georgia [VerfasserIn] |
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| | Schönberg, Stefan [VerfasserIn] |
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| | Hofmann, Wolf-Karsten [VerfasserIn] |
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| | Reiter, Andreas [VerfasserIn] |
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| | Riffel, Julia [VerfasserIn] |
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| Titel: | Low risk of contrast media-induced hypersensitivity reactions in all subtypes of systemic mastocytosis |
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| Verf.angabe: | Juliana Schwaab, Knut Brockow, Philipp Riffel, Johannes Lübke, Nicole Naumann, Mohamad Jawhar, Lukas Reiter, Alice Fabarius, Georgia Metzgeroth, Stefan O. Schoenberg, Wolf-Karsten Hofmann, Andreas Reiter, Julia Riffel |
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| E-Jahr: | 2022 |
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| Jahr: | March 2022 |
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| Umfang: | 5 S. |
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| Fussnoten: | Online verfügbar: 9. Oktober 2021, Artikelversion: 22. Februar 2022 ; Gesehen am 06.05.2024 |
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| Titel Quelle: | Enthalten in: Annals of allergy, asthma and immunology |
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| Ort Quelle: | Amsterdam [u.a.] : Elsevier, 1996 |
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| Jahr Quelle: | 2022 |
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| Band/Heft Quelle: | 128(2022), 3 vom: März, Seite 314-318 |
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| ISSN Quelle: | 1534-4436 |
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| Abstract: | Background - Patients with systemic mastocytosis (SM) are at increased risk of hypersensitivity reactions (HRs). Although Hymenoptera venoms are the predominant triggers, cases of contrast media-induced HR (CMIHR) have also been reported and prophylactic premedication is often performed. However, data from larger series are limited and differences between indolent and advanced SM have not yet been investigated. - Objective - To determine the incidence and severity of CMIHR in all subtypes of SM. - Methods - We analyzed 162 adult patients with SM (indolent systemic mastocytosis [ISM], n = 65; advanced systemic mastocytosis [advSM], n = 97). First, the cumulative incidence of CMIHR was retrospectively assessed in the patient's history. Second, at our institution, patients underwent 332 contrast media (CM)-enhanced imaging including 80 computed tomography (CT) scans with iodine-based contrast agent and 252 magnetic resonance imaging (MRI) with a gadolinium-based contrast agent, and tolerance was assessed. - Results - Previous CMIHRs to CT (vomiting, n = 1, erythema, n = 1, cardiovascular shock, n = 1), and MRI (dyspnea, n = 1, cardiovascular shock, n = 1) had been reported by 4 out of 162 (2.5%) patients (ISM, n = 3; advSM, n = 1). In contrast, during or after 332 CM-enhanced CT or MRI examinations at our institution, no CMIHRs were reported. Premedication was solely given to 3 patients before CT scans, including 1 with previous CMIHR, who tolerated the imaging well. - Conclusion - We conclude that: (1) there is a substantial discrepancy between the perception and prevalence of HRs to CM in SM; (2) reactions are scarce in ISM and even rarer in advSM; and (3) in SM patients without previous history of CM hypersensitivity, prophylactic premedication before CM-enhanced CT or MRI is dispensable. |
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| DOI: | doi:10.1016/j.anai.2021.10.004 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1016/j.anai.2021.10.004 |
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| | Volltext: https://www.sciencedirect.com/science/article/pii/S1081120621011340 |
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| | DOI: https://doi.org/10.1016/j.anai.2021.10.004 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| K10plus-PPN: | 1887862080 |
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| Verknüpfungen: | → Zeitschrift |
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Low risk of contrast media-induced hypersensitivity reactions in all subtypes of systemic mastocytosis / Schwaab, Juliana [VerfasserIn]; March 2022 (Online-Ressource)
