| Online-Ressource |
Titel: | Progress in the Chemistry of Organic Natural Products 115 |
Mitwirkende: | Kinghorn, A. Douglas [HerausgeberIn] |
| Falk, Heinz [HerausgeberIn] |
| Gibbons, Simon [HerausgeberIn] |
| Asakawa, Yoshinori [HerausgeberIn] |
| Liu, Ji-Kai [HerausgeberIn] |
| Dirsch, Verena M. [HerausgeberIn] |
Verf.angabe: | edited by A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Yoshinori Asakawa, Ji-Kai Liu, Verena M. Dirsch |
Ausgabe: | 1st ed. 2021. |
Verlagsort: | Cham |
| Cham |
Verlag: | Springer International Publishing |
| Imprint: Springer |
E-Jahr: | 2021 |
Jahr: | 2021. |
| 2021. |
Umfang: | 1 Online-Ressource(VII, 203 p. 127 illus., 26 illus. in color.) |
Gesamttitel/Reihe: | Progress in the Chemistry of Organic Natural Products ; 115 |
| Springer eBook Collection |
ISBN: | 978-3-030-64853-4 |
Abstract: | Total Synthesis of Decanolides (Nonanolides) with a Special Focus on Olefin Metathesis -- From Plant to Patient: Thapsigargin -- Antileishmanial Activity of Lignans and Neolignans -- Cryptolepine as a Lead to new Antiprotozoal Agents -- Biologically Active Constituents from Plants of the Genus Xanthium. |
| This book describes current understandings and recent progress into a varied group of natural products. In the first chapter the role that total synthesis may play in revising the structures proposed for decanolides, which are ten-membered lactones found primarily in fungi, frogs, and termites is presented. The following chapter presents the development of the intriguing plant-derived sesquiterpene lactone, thapsigargin, a potent inhibitor of the enzyme, SERCA (sarco-endoplasmic Ca2+ ATPase), which has potential as a lead compound to treat cancer. The third chapter covers the potential of various plant phenolic compounds for treating the tropical and sub-tropical infectious disease, leishmaniasis. In addition the volume presents recent advances related to the plant alkaloid, cryptolepine, which is of particular interest as a lead for the treatment of malaria, trypanosomiasis, and cancer. |
DOI: | doi:10.1007/978-3-030-64853-4 |
URL: | Resolving-System: https://doi.org/10.1007/978-3-030-64853-4 |
| DOI: https://doi.org/10.1007/978-3-030-64853-4 |
Datenträger: | Online-Ressource |
Sprache: | eng |
Bibliogr. Hinweis: | Erscheint auch als : Druck-Ausgabe |
| Erscheint auch als : Druck-Ausgabe |
| Erscheint auch als : Druck-Ausgabe |
K10plus-PPN: | 1756962944 |
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Lokale URL UB: | Zum Volltext |
Progress in the Chemistry of Organic Natural Products 115 / Kinghorn, A. Douglas [HerausgeberIn]; 2021. (Online-Ressource)