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Titel:Progress in the Chemistry of Organic Natural Products 115
Mitwirkende:Kinghorn, A. Douglas [HerausgeberIn]   i
 Falk, Heinz [HerausgeberIn]   i
 Gibbons, Simon [HerausgeberIn]   i
 Asakawa, Yoshinori [HerausgeberIn]   i
 Liu, Ji-Kai [HerausgeberIn]   i
 Dirsch, Verena M. [HerausgeberIn]   i
Verf.angabe:edited by A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Yoshinori Asakawa, Ji-Kai Liu, Verena M. Dirsch
Ausgabe:1st ed. 2021.
Verlagsort:Cham
 Cham
Verlag:Springer International Publishing
 Imprint: Springer
E-Jahr:2021
Jahr:2021.
 2021.
Umfang:1 Online-Ressource(VII, 203 p. 127 illus., 26 illus. in color.)
Gesamttitel/Reihe:Progress in the Chemistry of Organic Natural Products ; 115
 Springer eBook Collection
ISBN:978-3-030-64853-4
Abstract:Total Synthesis of Decanolides (Nonanolides) with a Special Focus on Olefin Metathesis -- From Plant to Patient: Thapsigargin -- Antileishmanial Activity of Lignans and Neolignans -- Cryptolepine as a Lead to new Antiprotozoal Agents -- Biologically Active Constituents from Plants of the Genus Xanthium.
 This book describes current understandings and recent progress into a varied group of natural products. In the first chapter the role that total synthesis may play in revising the structures proposed for decanolides, which are ten-membered lactones found primarily in fungi, frogs, and termites is presented. The following chapter presents the development of the intriguing plant-derived sesquiterpene lactone, thapsigargin, a potent inhibitor of the enzyme, SERCA (sarco-endoplasmic Ca2+ ATPase), which has potential as a lead compound to treat cancer. The third chapter covers the potential of various plant phenolic compounds for treating the tropical and sub-tropical infectious disease, leishmaniasis. In addition the volume presents recent advances related to the plant alkaloid, cryptolepine, which is of particular interest as a lead for the treatment of malaria, trypanosomiasis, and cancer.
DOI:doi:10.1007/978-3-030-64853-4
URL:Resolving-System: https://doi.org/10.1007/978-3-030-64853-4
 DOI: https://doi.org/10.1007/978-3-030-64853-4
Datenträger:Online-Ressource
Sprache:eng
Bibliogr. Hinweis:Erscheint auch als : Druck-Ausgabe
 Erscheint auch als : Druck-Ausgabe
 Erscheint auch als : Druck-Ausgabe
K10plus-PPN:1756962944
 
 
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