Papers by FARNAZ SADAT FATTAHI
Woolen yarns are the main material for the fabrication of nanocomposite blended yarns, multilayer... more Woolen yarns are the main material for the fabrication of nanocomposite blended yarns, multilayer fabrics and nanostructure nonwovens for the textiles and garments. This study was started in an effort to search the kinetic and thermodynamic characteristics of CI Acid Blue 106 (A leveling acid dye) on woolen yarns. Various models (zero order, first order, second order, Parabolic, cegarra-Puente, and modified cegarra-puente models) were used to recognize an appropriate dyeing apparatus. It was established that the modified cegarra-puente model top fitted to the studied information with the maximum correlation (R 2 ≥0.999). The dyeing-rate constant, the half dyeing times, rise time and fixation time were then considered. Also, thermodynamic parameters, such as the activation energy (Ea), were considered.
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فرضیه: در سالهای اخیر روشهای جدیدی مانند پلاسما، پرتودهی فرابنفش و عملآوری با ازن برای اصلاح س... more فرضیه: در سالهای اخیر روشهای جدیدی مانند پلاسما، پرتودهی فرابنفش و عملآوری با ازن برای اصلاح سطح پلیمرها بهکار گرفته شده است. اصلاح سطح الیاف پلیمری برای بهبود قابلیت رنگرزی و ایجاد خواص فیزیکی مطلوب مانند جذب رطوبت زیاد و الکتریسیته ساکن کم انجام میشود. در این مطالعه، برای اصلاح خواص سطحی الیاف پلیاستر و اکسایش سطحی آنها، روش ترکیبی جدیدی از راه عملآوری با فرابنفش-ازن با دو شیوه خشک و تر بهکار گرفته شده است.روشها: برای اصلاح سطح الیاف پلیاستر، عملآوری با فرابنفش-ازن روی نمونههای خشک و نیز پیشآغشتهسازی نمونهها با آب و محلولهای هیدروژن پراکسید و هیدروژن پراکسید-سدیم سیلیکات انجام شد. بهمنظور بررسی گروههای عاملی و شکلشناسی نمونهها و مقایسه آنها با نمونه شاهد بهترتیب از طیفنمایی زیرقرمز تبدیل فوریه (FTIR) و میکروسکوپی الکترون پویشی (SEM) استفاده شد. همچنین، جذب رطوبت و مقدار الکتریسیته ساکن نمونهها بررسی شد. یافتهها: نتایج طیفهای FTIR حاکی از افزایش شایان توجه گروههای عاملی اکسیژندار مانند هیدروکسیل و کربونیل در نمونهها در اثر عملآوری با فرابنفش-ازن بود. ...
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مطالعات در دنیای رنگ, Nov 21, 2020
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Gene therapy is a rapidly progressing field with vast prospective for fundamentally treating huma... more Gene therapy is a rapidly progressing field with vast prospective for fundamentally treating human diseases such as cancer, damaged tissues, and genetic syndromes. Between various approaches of gene delivery, there is a growing interest in oral administration of DNA as one of the safest and most straightforward methods. Nanoparticles are some of the important examples of nano-materials for molecule delivery (drugs, growth factors and DNA) used in biomedical applications. Several researchers have revealed the process of nanotechnology, specifically polymeric nanoparticles, as DNA delivery structures for transdermal routines. Polylactic acid (PLA) and its famous copolymer polylactic-co-glycolic (PLGA) are biocompatible synthetic polymers widely used to produce nanoparticles. Biobased, biosourced, biodegradable biocompatible, and bioabsorbable polylactide nanoparticles are one of the most promising materials in gene therapy serving as DNA delivery vehicles. Polylactide nanoparticles are easily processable and undergo degradation into natural metabolites while matching its degradation rate with the healing time of damaged human tissues. This mini review presents the new developments in the applications of polylactide nanoparticles as DNA delivery systems. In addition, the release of DNA from these nanoplatforms will be reported briefly.
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Nanofibrous meshes refer to the structures made of ultra-fine polymeric fibers. Because of nanome... more Nanofibrous meshes refer to the structures made of ultra-fine polymeric fibers. Because of nanometer measure size with an excessive strength/weight ratio, they are actual suitable as a nanosystem for delivering drug molecules. Drug molecules which mixed in nanofibers, can be released from the surrounding environment by means of various mechanisms in different manners (burst release, sustainable release and tunable release). Nanofibers can be used by way of release rate controlling strategies as proper delivery structures for drug molecules.The objective of this review is to highpoint the capacity of nanofibers as novel releasing substances for profens (Propionic acid derivative drugs including Carprofen; Naproxen; Fenoprofen; Flurbiprofen; Ibuprofen; Ketoprofen and Tiaprofenic acid). The profens are a class of nonselective, nonsteroidal anti-inflammatory drugs (NSAIDs). These drug molecules are derivatives of 2-phenylpropanoic acid. All contain a chiral center resulting in the formation of two enantiomers (R and S) of each profen. In this review, full information will be reported about the new progresses for release behaviors of profen molecules form the novel nanofibrous delivery systems. The drug releasing kinetics of profen molecules from nanofibers will be described briefly. The authors use more than 80 articles , books and thesis published in the case of nanofibrous profens delivery and releasing systems.
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UV/Ozone treatment is a fast and environmentally friendly technique for surface modification of p... more UV/Ozone treatment is a fast and environmentally friendly technique for surface modification of polymeric fibers and films .In this study, UV/Ozone treatment and important factors of this method are introduced and the mechanism of this process has been investigated from various aspects (chemical and physical). The formation of free radicals on the surface (due to photochemical interactions) and the formation of surface roughness (due to the effect of physical etching) are two key factors in the surface engineering of polymeric fibers and films by UV/Ozone irradiation. Furthermore, the applications of UV/Ozone treatment on polymeric fibers and films are briefly stated and as a case study, the researchers are discussed on modification of the surface properties of polymeric fibers and films via this method. This treatment can increase the dyeing depth of the fibers. Also, UV/Ozone treatment has been used to improve the antistatic and hydrophilic properties of polymeric fibers and films, and the results of these studies have been reviewed in this review.
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Hypothesis: In recent years, some modern techniques such as plasma, ultraviolet
irradiation and... more Hypothesis: In recent years, some modern techniques such as plasma, ultraviolet
irradiation and ozone treatment have been used in surface modifcation of
polymers. Surface modifcation of polymeric fbers is aimed to improve dying
and to achieve desirable physical properties like high moisture absorption and lower
anti-static. In this study in an attempt to modify the surface of polyester fbers, a new
complex method through ultraviolet/ozone treatment in two wet and dry forms has
been applied.
Methods: Surface modifcation of polyester fbers was performed by ultraviolet/ozone
treatment on dry samples, as well as on samples impregnated with water, hydrogen
peroxide and hydrogen peroxide/sodium silicate solutions. In order to study and
compare the functional groups and morphology of the polyester fbers with those of
control sample, Fourier-transform infrared spectroscopy (FTIR) and scanning electron
microscopy (SEM) were used. Also, the moisture absorption and static electricity of
the samples were studied.
Findings: The results of FTIR spectra revealed that by ultraviolet/ozone treatment
the number of oxygen-containing functional groups has increased considerably. Also,
nanoscale surface roughness of the treated samples was revealed by SEM images.
Additionally, the results indicated that moisture absorption of the treated polyester
fbers has risen and consequently their static electricity has decreased. According
to the results, the impregnation of polyester fbers can remarkably enhance surface
oxidation process.
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The usage of clinical devices in the cardiovascular treatment, hemodialyze system and other biome... more The usage of clinical devices in the cardiovascular treatment, hemodialyze system and other biomedical applications has improved recently. Direct contacts of biomaterials like poly(lactic acid) biopolymer with blood result in the activating of platelets, white blood cells , coagulation structure and complement cascades. Poly(lactic acid) is a sustainable, renewable, compostable, biobased, biodegradable, bioabsorbable , biocompatible polymer. This polymer has many applications in the synthesis of blood contacting mats like nanofibrous vascular scaffolds and hemodialyze nanosheets. Mechanical interruption of the blood vessel wall throughout grafting of cardiovascular devices starts local hemostatic replies. Improving the safety of the blood contacting nanostructure grafts is a main necessity. The controlling of the interactions of proteins and platelets to the surface of a blood contacting biomaterial is a significant factor. So, the assessments of these material's influences on blood are necessary. This article references more than 80 articles published in the last decade and reviews the latest hemocompatibility assays of poly(lactic acid) nanostructures used in the blood contacting field.
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Wound healing is a complicated procedure which necessitates laying
out a suitable wound hea... more Wound healing is a complicated procedure which necessitates laying
out a suitable wound healing system or dressing which possesses key
factors like a wet wound location, avoidance of microbial action and
absorption of exudates. Various wound dressings can be accessible but
not all can meet the particular conditions of a perfect wound healing
system to complete proper wound healing process. Poly(Lactic Acid)
(PLA) Nano Structure Mats are a new class of materials that possess
great potential in wound healing because of biocompatibility, bio
absorbability, biodegradability, absorption of exudates from the wound,
physical safety of the wounded tissue and the probability to free useful
molecules. Our review article gives a brief intro on the wound and skin
structure and afterwards gives information about the peerless
characteristics of PLA Nano Structure Mats remarkable for wound
healing. Moreover, new recent investigations about PLA Nano Structure
Mats usage for wound healing applications were also explored.
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In recent years, the adaptation of tissue engineering techniques is necessary
to progress the fie... more In recent years, the adaptation of tissue engineering techniques is necessary
to progress the field of cardio-vascular bio-logy and advancing patient care.
Through the high event of cardio-vascular disease and increasing amount of
patients needing vascular admission, there is a considerable require for smalldiameter
(<6mm inner diameter) vascular graft that can supply long-period
patency. Vascular tissue engineering is a novel field that has undergone massive
growth more than the final decade and has suggested suitable keys for bloodvessels
darn. The objective of vascular tissue engineering is to manufacture neovessels
and neo-organ tissue from autologous cells by means of a bio-degradable
polymer like Poly (lactic acid) (PLA) as a scaffold. PLA Nano-fibrous scaffolds have
high surface area–to-volume ratios and porosity that simulate the structure of
protein fibers in native extra cellular matrix (ECM). The versatilities of polymer
components, fiber structures, and functionalization have made the fabrication of
PLA Nano-fibrous scaffolds with suitable mechanical strength, transparency and
biological properties for vascular tissue engineering feasible. The most significant
benefit of tissue engineered implants is that these tissues can grow, remodel,
rebuild, and respond to damage. This review explains the fabrication, properties
and advantages of different types of PLA scaffolds with emphasis on Nano-fibrous
ones for vascular tissue engineering.
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How to cite this article Scanningelectron microscopy (SEM) has been utilized to examine the morph... more How to cite this article Scanningelectron microscopy (SEM) has been utilized to examine the morphology and topography alterations in the surface of Poly(Lactic Acid)(PLA) fabrics due to UV/Ozoneirradiation. In the past decade, a growing attention in the usage of "Green Techniques" in industrial applications has been observed owing to many benefits such as low impurities and their relatively low cost to substitute the conventional processes.The effects of UV/Ozone irradiation along with the pretreatments with distilled water, hydrogen peroxide, and hydrogen peroxide/sodium silicate solutions on the surface morphology of the PLA fibers by means of SEM were investigated and the images were compared with that of virgin untreated samples. The observations presented dramatically increase in insurface roughness andsurface area of the samples after the treatment. Nano-size roughening (827 nm) has been clearly observed on the samples. The changes in morphology mainly surface roughness and surface area, on the PLA fabrics surface due to UV/Ozone irradiation seem to be due mainly to the intensified etching effect of the UV/ Ozone process and these alterations maximized by the pretreatment of the fabrics with the hydrogen peroxide/sodium silicate solution.
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LAMBERT ACADEMIC PUBLISHING, 2020
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Papers by FARNAZ SADAT FATTAHI
irradiation and ozone treatment have been used in surface modifcation of
polymers. Surface modifcation of polymeric fbers is aimed to improve dying
and to achieve desirable physical properties like high moisture absorption and lower
anti-static. In this study in an attempt to modify the surface of polyester fbers, a new
complex method through ultraviolet/ozone treatment in two wet and dry forms has
been applied.
Methods: Surface modifcation of polyester fbers was performed by ultraviolet/ozone
treatment on dry samples, as well as on samples impregnated with water, hydrogen
peroxide and hydrogen peroxide/sodium silicate solutions. In order to study and
compare the functional groups and morphology of the polyester fbers with those of
control sample, Fourier-transform infrared spectroscopy (FTIR) and scanning electron
microscopy (SEM) were used. Also, the moisture absorption and static electricity of
the samples were studied.
Findings: The results of FTIR spectra revealed that by ultraviolet/ozone treatment
the number of oxygen-containing functional groups has increased considerably. Also,
nanoscale surface roughness of the treated samples was revealed by SEM images.
Additionally, the results indicated that moisture absorption of the treated polyester
fbers has risen and consequently their static electricity has decreased. According
to the results, the impregnation of polyester fbers can remarkably enhance surface
oxidation process.
out a suitable wound healing system or dressing which possesses key
factors like a wet wound location, avoidance of microbial action and
absorption of exudates. Various wound dressings can be accessible but
not all can meet the particular conditions of a perfect wound healing
system to complete proper wound healing process. Poly(Lactic Acid)
(PLA) Nano Structure Mats are a new class of materials that possess
great potential in wound healing because of biocompatibility, bio
absorbability, biodegradability, absorption of exudates from the wound,
physical safety of the wounded tissue and the probability to free useful
molecules. Our review article gives a brief intro on the wound and skin
structure and afterwards gives information about the peerless
characteristics of PLA Nano Structure Mats remarkable for wound
healing. Moreover, new recent investigations about PLA Nano Structure
Mats usage for wound healing applications were also explored.
to progress the field of cardio-vascular bio-logy and advancing patient care.
Through the high event of cardio-vascular disease and increasing amount of
patients needing vascular admission, there is a considerable require for smalldiameter
(<6mm inner diameter) vascular graft that can supply long-period
patency. Vascular tissue engineering is a novel field that has undergone massive
growth more than the final decade and has suggested suitable keys for bloodvessels
darn. The objective of vascular tissue engineering is to manufacture neovessels
and neo-organ tissue from autologous cells by means of a bio-degradable
polymer like Poly (lactic acid) (PLA) as a scaffold. PLA Nano-fibrous scaffolds have
high surface area–to-volume ratios and porosity that simulate the structure of
protein fibers in native extra cellular matrix (ECM). The versatilities of polymer
components, fiber structures, and functionalization have made the fabrication of
PLA Nano-fibrous scaffolds with suitable mechanical strength, transparency and
biological properties for vascular tissue engineering feasible. The most significant
benefit of tissue engineered implants is that these tissues can grow, remodel,
rebuild, and respond to damage. This review explains the fabrication, properties
and advantages of different types of PLA scaffolds with emphasis on Nano-fibrous
ones for vascular tissue engineering.
irradiation and ozone treatment have been used in surface modifcation of
polymers. Surface modifcation of polymeric fbers is aimed to improve dying
and to achieve desirable physical properties like high moisture absorption and lower
anti-static. In this study in an attempt to modify the surface of polyester fbers, a new
complex method through ultraviolet/ozone treatment in two wet and dry forms has
been applied.
Methods: Surface modifcation of polyester fbers was performed by ultraviolet/ozone
treatment on dry samples, as well as on samples impregnated with water, hydrogen
peroxide and hydrogen peroxide/sodium silicate solutions. In order to study and
compare the functional groups and morphology of the polyester fbers with those of
control sample, Fourier-transform infrared spectroscopy (FTIR) and scanning electron
microscopy (SEM) were used. Also, the moisture absorption and static electricity of
the samples were studied.
Findings: The results of FTIR spectra revealed that by ultraviolet/ozone treatment
the number of oxygen-containing functional groups has increased considerably. Also,
nanoscale surface roughness of the treated samples was revealed by SEM images.
Additionally, the results indicated that moisture absorption of the treated polyester
fbers has risen and consequently their static electricity has decreased. According
to the results, the impregnation of polyester fbers can remarkably enhance surface
oxidation process.
out a suitable wound healing system or dressing which possesses key
factors like a wet wound location, avoidance of microbial action and
absorption of exudates. Various wound dressings can be accessible but
not all can meet the particular conditions of a perfect wound healing
system to complete proper wound healing process. Poly(Lactic Acid)
(PLA) Nano Structure Mats are a new class of materials that possess
great potential in wound healing because of biocompatibility, bio
absorbability, biodegradability, absorption of exudates from the wound,
physical safety of the wounded tissue and the probability to free useful
molecules. Our review article gives a brief intro on the wound and skin
structure and afterwards gives information about the peerless
characteristics of PLA Nano Structure Mats remarkable for wound
healing. Moreover, new recent investigations about PLA Nano Structure
Mats usage for wound healing applications were also explored.
to progress the field of cardio-vascular bio-logy and advancing patient care.
Through the high event of cardio-vascular disease and increasing amount of
patients needing vascular admission, there is a considerable require for smalldiameter
(<6mm inner diameter) vascular graft that can supply long-period
patency. Vascular tissue engineering is a novel field that has undergone massive
growth more than the final decade and has suggested suitable keys for bloodvessels
darn. The objective of vascular tissue engineering is to manufacture neovessels
and neo-organ tissue from autologous cells by means of a bio-degradable
polymer like Poly (lactic acid) (PLA) as a scaffold. PLA Nano-fibrous scaffolds have
high surface area–to-volume ratios and porosity that simulate the structure of
protein fibers in native extra cellular matrix (ECM). The versatilities of polymer
components, fiber structures, and functionalization have made the fabrication of
PLA Nano-fibrous scaffolds with suitable mechanical strength, transparency and
biological properties for vascular tissue engineering feasible. The most significant
benefit of tissue engineered implants is that these tissues can grow, remodel,
rebuild, and respond to damage. This review explains the fabrication, properties
and advantages of different types of PLA scaffolds with emphasis on Nano-fibrous
ones for vascular tissue engineering.
produce polymeric nanofibers that show some potent properties such as high surface-to-volume ratio,
tunable porosity with diameter of 3 nm, 3D network forming, controllable diameter, fibre structure and
ease of surface functionalization. So, they can provide new opportunities for biomedical applications such
as controlled drug releasing systems, biodegradable surgical suture, wound dressing and tissue
engineering. Electrospun Nanofibres are ideal for tissue engineering scaffolds due to their intrinsic
properties. These materials are able to mimic the intricate fibrillar architecture of natural extracellular
matrix (ECM) components. In addition, they provide enough support for cell culture, adhesion, migration,
proliferation, differentiation and new 3D-tissue formation. This article presents a review on the category
of production, application and properties of electrospun nanofibrous scaffolds for tissue engineering.
Also, recent achievements will be described briefly.
is now emerging as a new treatment. Polymeric biomaterials (scaffolds) and living cells are used
for this purpose. The aim of this study was to investigate the application of polylactic acid
bioactive scaffolds in the regeneration of various tissues. Polylactic acid is a synthetic
biopolymer that has been proposed in recent years as an important proposition in the production
of tissue engineering scaffolds. This polymer is a biocompatible, biodegradable and biosorbable
material that is completely hydrolyzed in the living organism and decomposed into water and
carbon dioxide molecules. The production of bioactive polylactic acid scaffolds that are able to
chemically bond with host cells after in vivo implantation is a very new method in cell therapy.
This method has a great impact on the process and speed of repair of various tissues such as
urethral tissue, abdominal wall tissue, periodontal ligament, heart tissue, corneal tissue, bladder
tissue, vascular tissue, tendon tissue, cartilage tissue, skin tissue, nerve tissue and has bone tissue.
In this review, the latest and most prominent research of clinical scientists in the world in 2020
and 2021, in order to produce bioactive scaffolds of polylactic acid for regeneration of body
tissues will be summarized.