Just some initial impressions. Small things that I think would help take this from amazing to perfect.
One thing I thought was off was that all the dialogue of me clicking and the game responding was in past tense. I think it would make more sense if it was in current tense.
On the picture frame where you need to undo the latches, maybe let the player unlock them in any order?
And then I got stuck in the flesh tunnel. Couldn't tear down the web or use the bottle with the key I found (no way to use items) and I couldn't back out, I'd stop moving after a point.