Pelayanan Kefarmasian di Rumah (Home Pharmaceutical Care) bagi Pasien Diabetes Melitus Tipe 2

NUR RASDIANAH, Prof. Dr. Suwaldi Martodihardjo, M.Sc.,Apt.; Dr. Tri Murti Andayani, Sp.FRS.,Apt.;Prof. Dr. Lukma
Universitas Gadjah Mada, 2019 | Diunduh dari http://etd.repository.ugm.ac.id/

DAFTAR ISI

HALAMAN SAMPUL.................................................................................. . i
HALAMAN PERSETUJUAN ...................................................................... ii
HALAMAN PERNYATAAN ........................................................................ iii
KATA PENGANTAR .................................................................................... iv
DAFTAR ISI ................................................................................................... vii
DAFTAR TABEL .......................................................................................... xi
DAFTAR GAMBAR ..................................................................................... xiii
DAFTAR LAMPIRAN .................................................................................. xiv
DAFTAR SINGKATAN ............................................................................... xv
INSTISARI ..................................................................................................... xvi
ABSTRACT .................................................................................................... xvii

BAB I PENDAHULUAN .......................................................................... 1

A. Latar Belakang ........................................................................... 1
1. Perumusan Masalah .............................................................. 5
2. Keaslian penelitian ................................................................ 5
3. Urgensi Penelitian ................................................................. 9
B. Tujuan Penelitian ......................................................................... 10
BAB II TINJAUAN PUSTAKA ............................................................... 11
A. Telaah Pustaka ............................................................................ 11
1. Pelayanan Kefarmasian ......................................................... 11
2. Home care ............................................................................. 14
3. Diabetes Melitus Tipe ........................................................... 19
4. Permasalahan Terkait Pengobatan ........................................ 25
5. Edukasi................................................................................... 26
6. Kepatuhan ............................................................................. 32
7. Kepuasan terapi ..................................................................... 45
B. Landasan Teori........................................................................... 48
 Pelayanan Kefarmasian di Rumah (Home Pharmaceutical Care) bagi Pasien Diabetes Melitus Tipe 2
NUR RASDIANAH, Prof. Dr. Suwaldi Martodihardjo, M.Sc.,Apt.; Dr. Tri Murti Andayani, Sp.FRS.,Apt.;Prof. Dr. Lukma
Universitas Gadjah Mada, 2019 | Diunduh dari http://etd.repository.ugm.ac.id/

C. Kerangka Konsep ....................................................................... 53

D. Keterangan Empiris dan Hipotesis ............................................ 53

BAB III METODE PENELITIAN.............................................................. 55

A. Identifikasi Masalah dan Hambatan Pengobatan
Diabetes Melitus Tipe 2 ............................................................. 56
1. Alur Penelitian ...................................................................... 56
2. Desain Penelitian ................................................................... 57
3. Populasi dan Subjek Penelitian ............................................. 58
4. Lokasi dan Waktu Penelitian ................................................ 58
5. Bahan dan Alat Penelitian ..................................................... 59
6. Uji Validitas dan Realibilitas Instrumen Penelitian .............. 61
7. Implikasi Etik Pada Manusia ................................................ 63
8. Prosedur Penelitian................................................................ 63
9. Definisi Operasional Penelitian ............................................ 65
10. Analisis Data ........................................................................ 66
B. Penyusunan Pedoman Pelayanan Kefarmasian ....................... 67
1. Penyusunan dan Review Pedoman....................................... 68
2. Ujicoba Pedoman .................................................................. 69
C. Penerapan Pedoman Pelayanan Kefarmasian ............................ 76
1. Waktu dan Lokasi Penelitian ................................................ 76
2. Rancangan Penelitian ............................................................ 78
3. Subjek Penelitian.................................................................. 78
4. Sumber Data dan Instrumen Penelitian ................................. 80
5. Definisi Operasional Penelitian............................................. 81
6. Prosedur Penerapan Pedoman Pelayanan Kefarmasian di
Rumah ................................................................................... 83
7. Analisis dan Penyajian Data .................................................. 90

BAB IV HASIL PENELITIAN DAN PEMBAHASAN ............................ 93

A. Identifikasi Masalah dan Hambatan Pengobatan
Diabetes Melitus Tipe 2 ............................................................. 93
 Pelayanan Kefarmasian di Rumah (Home Pharmaceutical Care) bagi Pasien Diabetes Melitus Tipe 2
NUR RASDIANAH, Prof. Dr. Suwaldi Martodihardjo, M.Sc.,Apt.; Dr. Tri Murti Andayani, Sp.FRS.,Apt.;Prof. Dr. Lukma
Universitas Gadjah Mada, 2019 | Diunduh dari http://etd.repository.ugm.ac.id/

1. Deskripsi Partisipan ............................................................... 93

2. Masalah terkait dengan pengobatan diabetes melitus tipe 2.. 104
B. Penyusunan Draft Pedoman Pelayanan Kefarmasian ................. 113
1. Penilaian Pedoman ................................................................. 113
2. Uji Coba Pedoman .................................................................. 116
C. Penerapan Pedoman Pelayanan Kefarmasian ............................. 126
1. Gambaran Umum Partisipan Sebelum Penerapan Pedoman .. 127
a. Karakteristik Partisipan ..................................................... 138
b. Tingkat Pengetahuan, Kepatuhan Pengobatan, Kepuasan
Terapi, dan Luaran Klinik ................................................. 141
i. Tingkat pengetahuan tentang diabetes ......................... 144
ii. Kepatuhan pengobatan ................................................ 148
iii. Kepuasan terapi........................................................... 150
iv. Luaran klinik (kadar GDP dan HbA1c) ..................... 144
2. Periode Penerapan Pedoman Pelayanan Kefarmasian .......... 150
3. Periode Setelah Penerapan Pedoman Pelayanan Kefarmasian 154
a. Pengaruh penerapan pelayanan kefarmasian terhadap
pengetahuan....................................................................... 156
b. Pengaruh penerapan pelayanan kefarmasian terhadap
kepatuhan .......................................................................... 163
c. Pengaruh penerapan pelayanan kefarmasian terhadap
kepuasan terapi ................................................................. 173
d. Pengaruh penerapan pelayanan kefarmasian terhadap
luaran klinik (GDP, HbA1c) ............................................. 176
D. Keterbatasan Penelitian .............................................................. 191

BAB V PEMBAHASAN UMUM .............................................................. 193

BAB VI KESIMPULAN DAN SARAN ...................................................... 200
A. Kesimpulan.................................................................................... 200
B. Saran............................................................................................... 202
C. Perspektif ....................................................................................... 202
 Pelayanan Kefarmasian di Rumah (Home Pharmaceutical Care) bagi Pasien Diabetes Melitus Tipe 2
NUR RASDIANAH, Prof. Dr. Suwaldi Martodihardjo, M.Sc.,Apt.; Dr. Tri Murti Andayani, Sp.FRS.,Apt.;Prof. Dr. Lukma
Universitas Gadjah Mada, 2019 | Diunduh dari http://etd.repository.ugm.ac.id/

DAFTAR PUSTAKA ..................................................................................... 203

LAMPIRAN..................................................................................................... 208
RINGKASAN.................................................................................................. 326
NASKAH PUBLIKASI.................................................................................. 335