Hello @thornemann. We have already been in communication on this subject in the other forum topic where you commented, but for the benefit of other interested parties who might be following this topic I thought I should also add a note here that the Arduino Cloud developers have fixed the bug. You should now be able to upload to use Arduino Cloud Editor to upload ESP32 boards without encountering that "No such file or directory" error message.
Please let us know if you still encounter any problems using Arduino Cloud.
I apologize for any inconvenience this bug has caused.
Regards, Per