Error compiling for board Arduino/Genuino Uno.

Hi,
please any one help me to resolve my problum
Iam having 3 Arduino boards non is working and giving the following ERROR

Cannot create temporary file in C:\Users\mkbutan\AppData\Local\Temp: Permission denied

exit status 3
Error compiling for board Arduino/Genuino Uno.

Arduino Uno 328p

I have installed Arduino 1.8.5 IDE on my New Laptop
Lenovo ideapad 320
i-3 ; 8GB RAM ; 2TB HDD
Win-10 (64Bits)

It was working before on my Desktop
Win-7(32Bits)

Assembler messages:

Fatal error: can't create core\wiring_pulse.S.o: Permission denied

exit status 1
Error compiling for board Arduino/Genuino Uno.

This sort of error could be caused by your antivirus software. Try TEMPORARILY disabling your antivirus for a single compilation to see if the problem goes away, then turn the antivirus back on. If the problem doesn't occur with the antivirus off you will need to adjust the settings of your antivirus to whitelist the appropriate file, folder, or process so it doesn't interfere with compilation.

hi dear Pert
thanks for the reply
still its the same even after disabling the AV for 15 Min.
its giving the same ERROR

Try running the Arduino IDE as administrator.

open sketch\Blink.ino.cpp: Access is denied.
Error compiling for board Arduino/Genuino Uno.

Assembler messages:

Fatal error: can't create core\PluggableUSB.cpp.o: Permission denied

exit status 1
Error compiling for board Arduino/Genuino Uno.

Quick Heal Total Security is Disabled and still this EROOR

C:\Users\mkbutan\Documents\ArduinoData\packages\arduino\hardware\avr\1.6.21\cores\arduino\WInterrupts.c:1:0: fatal error: can't open C:\Users\mkbutan\AppData\Local\Temp\ccdJH3IS.s for writing: Permission denied

/* -- mode: jde; c-basic-offset: 2; indent-tabs-mode: nil -- */

^

compilation terminated.

exit status 1
Error compiling for board Arduino/Genuino Uno.

Is that when you ran the Arduino IDE as administrator?

yes

This application has requested the Runtime to terminate it in an unusual way.
Please contact the application's support team for more information.

Cannot create temporary file in C:\Users\MKButan\AppData\Local\Temp: Permission denied

exit status 3
Error compiling for board Arduino Duemilanove or Diecimila.

Now iam getting the same thing in Desktop also
Please Help to solve the Problem

Build options changed, rebuilding all
C:\Users\MKButan\AppData\Local\Arduino15\packages\arduino\hardware\avr\1.6.21\cores\arduino\hooks.c:1:0: fatal error: can't open C:\Users\MKButan\AppData\Local\Temp\ccjHKI6T.s for writing: Permission denied

/*

^

compilation terminated.

exit status 1
Error compiling for board Arduino/Genuino Uno.

Dont know what to do???

Sorry, I'm stumped. Maybe someone else here will be able to help.

Thank you Pert
Disabling Antivirus helped me
Thanks a lot