Movies Gallery 22 of the best sets of big-screen sisters The bond of sisters ranges from BFFs to frenemies and everything in between. Together, these cinematic siblings have shown that fewer things are stronger than family. By Madeline Boardman Madeline Boardman Madeline Boardman is a former digital features director at Entertainment Weekly. She left EW in 2017. EW's editorial guidelines Updated on July 27, 2022 11:30AM EDT Close Photo: CLOCKSWISE FROM LEFT: Disney/Marvel; EVERETT COLLECTION; Disney; Lorey Sebastian; K.C. Bailey Great films about sisters span multiple genres, from cheeky comedies to tear-jerking melodramas. Sisterhood can be messy, beautiful, complicated, and life-affirming, sometimes all at the same time, and film history has a wide variety of depictions of this unique bond. This list includes classics like the March sisters of Little Women — who have been adapted many times to the screen — alongside more modern creations like Elsa and Anna from Frozen, all telling their own unique stories of what it means to be a sister. Here are our picks for the 22 best sets of sisters on film, presented in no particular order. 01 of 21 Hippolyta and Antiope in Wonder Woman (2017) Clay Enos/Warner Bros.; Alex Bailey/Warner Bros. How exactly did Wonder Woman build up that ferocious spirit? The answer lies in her mother Hippolyta (Connie Nielsen) and aunt Antiope (Robin Wright), among the many other strong women who populate the island of Themyscira. The sisters' relationship is tenuous, with Antiope eager to train a young Diana and Hippolyta doing her best to protect her daughter, but their influence is no doubt present every time their love shines through the girl who would be Wonder Woman. 02 of 21 Gamora and Nebula in Guardians of the Galaxy Vol. 2 (2017) Disney/Marvel There's a lot to be said for the complex relationship between the green-skinned Guardian of the Galaxy (Zoe Saldana) and her assassin sister (Karen Gillan). Childhood rivalries, shared baggage from father Thanos, and still the long-lingering hope of redemption hang over the pair. All things considered, the sisters grapple with fairly relatable problems — they just happen to be aliens. 03 of 21 Tina and Queenie in Fantastic Beasts and Where to Find Them (2016) Warner Bros. Tina (Katharine Waterston) is an ex-Auror who simply cared too much; Queenie (Alison Sudol) is a powerful mind-reader who quite literally feels for everyone. Together, the supernatural sisters form a compassionate portrait of what life looked like for young witches hiding out in the Roaring '20s, where their abilities demand secrecy in public, but their magic blossoms in private. 04 of 21 Kate and Maura in Sisters (2015) K.C. Bailey/Universal Pictures Longtime pals and collaborators, Tina Fey and Amy Poehler took their relationship a step further when they played onscreen sisters Kate and Maura in the aptly titled Sisters. The comedy centers on the dynamic duo throwing one last bash at their childhood home before their parents put it up for sale. 05 of 21 Anna and Elsa in Frozen (2013) Disney In Disney's megahit Frozen, Princess Anna serenades her sister, Princess Elsa, with the tune "Do You Want to Build a Snowman?" — giving sisters everywhere a new anthem. Arguably two of the more famous sisters in recent film history, Anna and Elsa, voiced by Kristen Bell and Idina Menzel, respectively, form a long-awaited bond and stand by each other in the face of menacing men and dangerous powers. 06 of 21 Allison and Debbie/Sadie and Charlotte in Knocked Up (2007) Universal/Courtesy Everett Collection While Katherine Heigl and Leslie Mann lead Knocked Up as sisters Alison and Debbie, it is Debbie's daughters Sadie and Charlotte, played by real-life sisters Maude and Iris Apatow (the daughters of Mann and writer-director Judd Apatow), that are the true stars in our eyes. Whether they're telling it like it is or telling it like it's really not when it comes to childbirth ("You have to dig and you find the little baby!"), Sadie and Charlotte have a sisterly relationship for the ages. 07 of 21 Milly, Maggie, and Mae in Because I Said So (2007) Suzanne Tenner/Universal Pictures Mandy Moore, Lauren Graham, and Piper Perabo were the three sisters of a millennial girl's dream in 2007's Because I Said So. The stars played Milly, Maggie, and Mae, the daughters of Diane Keaton's Daphne Wilder. As the title suggests, their mother Daphne (Diane Keaton) offers many unsolicited opinions and instructions to the girls, providing the simple reason of "because I said so," pushing them into new relationships and down different paths. 08 of 21 Maggie and Rose in In Her Shoes (2005) Sidney Baldwin/Fox Cameron Diaz plays Maggie, the wild-child answer to Toni Collette's responsible Rose in 2005's In Her Shoes. While the rival sisters don't think they have much in common other than the same shoe size, they eventually come to realize that they share so much more. 09 of 21 Elizabeth, Jane, Kitty, Lydia, and Mary in Pride and Prejudice (2005) Focus Films/Courtesy Everett Collection Keira Knightley, Rosamund Pike, Carey Mulligan, Jena Malone, and Talulah Riley become the Bennet sisters for the 2005 adaptation of Jane Austen's beloved tale. Each actress perfectly captured their distinct character, with Knightley earning an Oscar nomination for her performance as the witty Elizabeth. 10 of 21 Kiki and Gwen in America's Sweethearts (2001) Columbia Pictures/Courtesy Everett Collection In 2001's America's Sweethearts, Kiki (Julia Roberts) is the awkward yet devoted personal assistant to her glamorous movie star sister Gwen (Catherine Zeta-Jones). While helping Gwen and her estranged hubby Eddie (John Cusack) — who are going through a messy divorce — promote their latest movie together, Kiki finally gets her moment in the spotlight when Gwen's famous ex takes an interest in her. 11 of 21 Eve, Georgia, and Maddy in Hanging Up (2000) Columbia Pictures/Courtesy Everett Collection A dream team of stars, Meg Ryan, Diane Keaton, and Lisa Kudrow play sisters Eve, Georgia, and Maddy in Hanging Up, the 2000 movie that Keaton also directed. Together, the three successful women, who communicate almost exclusively through clipped phone calls, must figure out how to come to terms with the tumultuous relationships they have with their father when he is on his deathbed. 12 of 21 Kat and Bianca in 10 Things I Hate About You (1999) Touchstone Pictures/Courtesy Everett Collection Julia Stiles and Larisa Oleynik play Kat and Bianca, two very different sisters, in 1999's 10 Things I Hate About You. In this modern spin on The Taming of the Shrew, Bianca wants the typical high school experience while Kat wants none of it, creating a problem for the two as their father says Bianca can only socialize when Kat does. They find common ground in the end, finally sticking up for each other against a shared enemy. 13 of 21 Annie and Hallie in The Parent Trap (1998) Lorey Sebastian A young Lindsay Lohan followed in the grand tradition of Hayley Mills and played twin sisters separated at birth in 1998's The Parent Trap. When the girls — prim and proper Annie and laid-back California girl Hallie — come face-to-face at summer camp, they scheme to reunite their divorced parents. 14 of 21 Teri, Maxine, and Bird in Soul Food (1997) 20th Century Fox/Courtesy Everett Collection Vanessa Williams, Vivica A. Fox, and Nia Long teamed up to play sisters Teri, Maxine, and Bird in the 1997 movie Soul Food. After they stop gathering for Sunday dinner each week following a family tragedy, the women find themselves at odds and start to drift apart. But they eventually reunite when Maxine's son schemes to use their Sunday soul food feasts as a way to bring them all back together. 15 of 21 Jo, Meg, Amy, and Beth in Little Women (2019) Wilson Webb/Sony Preceded by other adaptations of the beloved story, the foursome of Saoirse Ronan, Emma Watson, Florence Pugh, and Eliza Scanlan brought the famed sisters of Little Women to the big screen once again in 2019. The stars play the Louisa May Alcott-created characters of Jo, Meg, Amy, and Beth March, as they deal with disease, jealousy, and growing up in the Civil War era. 16 of 21 Winifred, Mary, and Sarah in Hocus Pocus (1993) Buena Vista/Courtesy Everett Collection Bette Midler, Kathy Najimy, and Sarah Jessica Parker make up the magical trio of Winifred, Mary, and Sarah in 1993's Hocus Pocus. The actresses play the now-iconic Sanderson sisters, three witches who terrorize children and practice dark magic. 17 of 21 Sally and Gillian in Practical Magic (1998) Warner Bros/Courtesy Everett Collection The Sanderson sisters have a bit of competition in Practical Magic's Sally and Gillian, played by Sandra Bullock and Nicole Kidman. While growing up with their aunts, the sisters learn witchcraft—and must face their family's famous curse. 18 of 21 Dottie and Kit in A League of Their Own (1992) John Biever/Columbia Pictures Geena Davis and Lori Petty play Dottie and Kit in the baseball flick A League of Their Own. Growing up in an Oregon farm town, the sisters' paths diverge when they are scouted for a women's baseball league. The two face off as leaders of the Peaches and Belles in the World Series, handling their complicated relationship on the baseball diamond. 19 of 21 Hannah, Lee, and Holly in Hannah and Her Sisters (1986) Courtesy Everett Collection Hannah (Mia Farrow) has a complicated relationship with her sisters Lee (Barbara Hershey) and Holly (Dianne Wiest) in the 1986 Woody Allen movie Hannah and Her Sisters. Amid affairs, betrayal, and far too much romantic crossover between the siblings, they remain close to one another, tracing their paths over the course of two years, which begins and ends with a Thanksgiving dinner. 20 of 21 Betty and Judy in White Christmas (1954) Courtesy Everett Collection Rosemary Clooney and Vera-Ellen are the unstoppable duo of Betty and Judy in 1954's White Christmas. Starring opposite Bing Crosby and Danny Kaye in the Irving Berlin musical, the two play young women who perform a sister act following World War II. Their collaboration gifted women everywhere with the anthem "Sisters," complete with the lyrics, "Many men have tried to split us up, but no one can/Lord help the mister who comes between me and my sister." 21 of 21 Esther, Tootie, Rose, and Agnes in Meet Me in St. Louis (1944) Everett Collection Judy Garland, Margaret O'Brien, Lucille Bremer, Joan Carroll come together as sisters Esther, Tootie, Rose, and Agnes in the 1944 classic Meet Me in St. Louis. The musical follows the four daughters of the affluent Smith family as they begin early romances, attend holiday balls, and navigate their family's imminent move to New York.