'X-Men Origins: Wolverine': Mutants and maniacs

Sabretooth/Victor Creed
Liev Schreiber (Defiance)
Endowed with superhuman senses and the claws and fangs of a prehistoric predator, the fierce assassin is consumed by a lifelong rivalry with his half brother, Wolverine.

William Stryker
Danny Huston (Children of Men)
The archvillain Army colonel presides over the covert-ops program that turns mutants into killing machines. Why his vendetta? He feels his mutant son drove his wife to suicide.

Kayla Silverfox
Lynn Collins (HBO’s True Blood)
Wolverine’s mysterious true love is a schoolteacher who calms his demons, but when she falls prey to Sabretooth, a vengeful Wolverine joins the top secret Weapon X program.

Deadpool/Wade Wilson
Ryan Reynolds (Definitely, Maybe)
A fellow initiate of the Weapon X program with Wolverine, this wisecracking, sword-wielding mercenary also possesses the ability to heal himself.

Gambit/Remy LeBeau
Taylor Kitsch (NBC’s Friday Night Lights)
The charismatic Cajun criminal, a fan favorite from the comics, can manipulate kinetic energy to transform any object into a lethal weapon — from a set of playing cards to his own fist.

Bradley
Dominic Monaghan (ABC’s Lost)
A former Team X member who can conduct and generate electricity, this lonely mutant goes underground as a circus performer after participating in some harrowing assignments.