Eusebi Ocaña Alcobé

On June 18th, the new transparency rules for the European clinical trials database 𝗖𝗧𝗜𝗦 (Clinical Trials Information System) came into force. According to the new CTIS standards, some documents will be published along with trial data keys, 𝘀𝗶𝗺𝗽𝗹𝗶𝗳𝘆𝗶𝗻𝗴 𝘁𝗵𝗲 𝗰𝗿𝗲𝗮𝘁𝗶𝗼𝗻 𝗮𝗻𝗱 𝘀𝘂𝗯𝗺𝗶𝘀𝘀𝗶𝗼𝗻 𝗼𝗳 𝗿𝗲𝗾𝘂𝗲𝘀𝘁𝘀. We are experts in 𝗰𝗹𝗶𝗻𝗶𝗰𝗮𝗹 𝘁𝗿𝗶𝗮𝗹 𝘀𝘁𝗮𝗿𝘁-𝘂𝗽. Trust your clinical research projects with APICES CRO.  Check the new regulations here ⬇️ #CRO #ClinicalStudies #ClinicalTrials #puestaenmarcha 🇪🇸 | El 18 de junio entraron en vigor las nuevas normas de transparencia de la base de datos europea de ensayos clínicos (CTIS). Siguiendo las nuevas normas de 𝗖𝗧𝗜𝗦, se harán públicos algunos documentos, que se publicarán junto con datos clave del ensayo. De esta forma, 𝘀𝗲 𝘀𝗶𝗺𝗽𝗹𝗶𝗳𝗶𝗰𝗮 𝗹𝗮 𝗰𝗿𝗲𝗮𝗰𝗶𝗼́𝗻 𝘆 𝗲𝗻𝘃í𝗼 𝗱𝗲 𝘀𝗼𝗹𝗶𝗰𝗶𝘁𝘂𝗱𝗲𝘀. Somos especialistas en 𝗽𝘂𝗲𝘀𝘁𝗮 𝗲𝗻 𝗺𝗮𝗿𝗰𝗵𝗮 𝗱𝗲 𝗲𝗻𝘀𝗮𝘆𝗼𝘀 𝗰𝗹í𝗻𝗶𝗰𝗼𝘀. ¡Confía tus proyectos de investigación clínica a APICES CRO! Consulta la nueva normativa aquí ⬇️ #EnsayosClínicos #EstudiosClínicos #InvestigaciónClínica #CTIS

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🆕 Grupo Menarini España and the Germans Trias i Pujol Research Institute (IGTP) have signed an agreement which encompasses two projects focusing on severe infections and antibiotic resistance. Both studies were presented within the framework of the "Scientific exchanges: join us" program, a series of internal meetings showcasing Menarini's scientific collaborations. Dr Mª Lluïsa Pedro-Botet, Roger Cortès Tarragó, Dr Noemí Párraga, and Dr Esteban Reynaga, researchers from the Clinical and Environmental Infectious Diseases (CEID) group at IGTP and Hospital Universitari Germans Trias i Pujol, explained the objectives of their projects. 🗣️ Jordi Barretina, general director of IGTP, states that this agreement with Menarini "strengthens our commitment to excellent research in key areas such as severe infections and antibiotic resistance. This public-private collaboration provides us with a valuable opportunity to continue advancing in the fight against global health challenges". Read more: https://lnkd.in/dDeXQT5M #Research #InfectiousDiseases #Legionella #AntibioticResistance

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𝗜𝗻𝗻𝗼𝘃𝗮𝘁𝗶𝗼𝗻 𝗮𝗻𝗱 𝗰𝗵𝗮𝗹𝗹𝗲𝗻𝗴𝗲𝘀 𝗼𝗳 𝘁𝗵𝗲 𝗜𝗩𝗗 𝘀𝗲𝗰𝘁𝗼𝗿 𝗶𝗻 𝗦𝗽𝗮𝗶𝗻 🔬 📣 The article co-authored by Beatriz Rodriguez Grande, NAMSA and me has been featured in the latest issue of #PMFarma. 💡 𝗛𝗶𝗴𝗵𝗹𝗶𝗴𝗵𝘁𝘀 ✅ IVDs represent the largest growing segment in the #MedTech sector worldwide in terms of CAGR and sales. ✅ Holding a robust 10.9% share of the #European market and approximately 2% of the global IVD market as of 2021, #Spain stands as the fourth major player in Europe, following Germany, France, and Italy. ✅ In Spain’s IVD sector, industry leaders such as Grífols and Werfen play a significant role, yet it’s the vibrant ecosystem of #SMEs that forms the backbone of #innovation and growth. ✅ The trends driving the #growth of the IVD sector include early diagnosis, growth of personalized medicine and emergence of artificial intelligence. Discover the full narrative and more in-depth analysis in the article available on pages 46-49 of the journal’s website version: https://lnkd.in/d-vhKCGy

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Chemistry

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📢𝗢𝗺𝗮𝗸𝗮𝘀𝗲 𝗽𝗮𝗿𝘁𝗶𝗰𝗶𝗽𝗮𝘁𝗲𝘀 𝗶𝗻 𝗕𝗵𝗲𝗺𝗼𝗴𝗲𝗻 𝗣𝗿𝗼𝗷𝗲𝗰𝘁, 𝗮𝗻 𝗶𝗻𝗻𝗼𝘃𝗮𝘁𝗶𝘃𝗲 𝗽𝗿𝗼𝗷𝗲𝗰𝘁 𝗶𝗻 𝗽𝗶𝗼𝗻𝗲𝗲𝗿𝗶𝗻𝗴 𝗴𝗲𝗻𝗲 𝘁𝗵𝗲𝗿𝗮𝗽𝘆 𝗳𝗼𝗿 𝗛𝗮𝗲𝗺𝗼𝗽𝗵𝗶𝗹𝗶𝗮 𝗕, 𝘀𝗽𝗼𝗻𝘀𝗼𝗿𝗲𝗱 𝗯𝘆 𝗖𝗦𝗟 𝗕𝗲𝗵𝗿𝗶𝗻𝗴.⁣ ⁣ We share publications related to the Bhemogen Project (Best Way for Gene Therapy in Haemophilia B), a project sponsored by CSL Behring which Omakase Consulting has had the privilege of coordinate and co-create with a multidisciplinary team of experts and key stakeholders in the fields of Haemophilia B and gene therapy in Spain. Becoming the first gene therapy targeting Haemophilia B represents disruptive innovation, not only from a therapeutic point of view but from the perspective of patient care and healthcare structures, resources and governance management. A “first” that, as many times before in other fields, represents both opportunities, challenges, learnings and ground opening. ⁣ ⁣ The project focused on developing a roadmap to prepare the Spanish healthcare system to adequately deliver gene therapy to candidate patients with haemophilia B, identify key actions needed and, most importantly, offering effective solutions to address them. ⁣ ⁣ ⁣1) https://lnkd.in/dp9JMWfz 2) https://lnkd.in/dwJBhdHV 3) https://lnkd.in/dcesJ3gq ⁣ #Genetherapy #HaemophiliaB #Carepathways #Hojaderuta #Spain

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Our colleague Juan Carlos Triviño, PhD, BioInformatic Expert in Sistemas Genómicos | member of SYNLAB, is leading session #3: "Beyond DNA: Regulatory-region analysis and its possible impact on clinical diagnosis", of our symposium: "NEW TECHNOLOGIES AND APPROACHES IN CLINICAL GENOMICS" at ESHG2024. Regulatory-region analysis is not just a tool, but a key to unlocking a comprehensive understanding of genetic diseases. By including these regions in genetic testing, we can significantly enhance diagnostic accuracy, inform personalized treatment strategies, and provide invaluable insights for genetic counselling. As sequencing technologies and bioinformatics tools continue to advance, the ability to detect and interpret regulatory mutations will improve, leading to better clinical outcomes and more precise medical interventions. More info: [email protected] We look forward to seeing you at our booth #570 #ESHG2024 #Genetic #SistemasGenomicos

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What pride that our QuimioProcess solution is a fundamental part of this oncoholistic concept, which fits safety for patients and healthcare professionals.

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Research and clinical studies are part of the foundation of our work at Brainlab and are essential to advancing healthcare. That's why Brainlab teamed up with Hospital Universitari Vall d'Hebron as clinical research partners. Hospital Universitari Vall d'Hebron is the biggest hospital in Catalonia, Spain and has fantastic research and pediatric departments. This allows us to gather vital data on treating children using our technology. This clinical cooperation began last year and together we have been researching anatomical mapping in lesion and cranial landmark detection for the development of functions such as tumor segmentation. We have already been able to collect data on 140 pediatric cases on top of a multitude of adult cases. A huge thanks to everyone involved in this clinical project: Fran Martinez Ricarte,MD, Jorge Andrés Cabrera Cárdenas, MD, Margarita Figueroa Vezirian, MD, Fuat Arikan Abelló, MD, Raquel Cánovas Paradell, Maria Antonia Poca Pastor, MD and @Diego Lopez Bermeo, MD. Looking forward to seeing what we can accomplish together! Want to learn more about Brainlab as a research partner? Click here: https://lnkd.in/gAg_-3CQ #TogetherWithBrainlab #medtech #digitalhealth #research #clinicalresearch #anatomicalmapping

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Annovis Bio will present two posters at the upcoming #CTAD2024 conference, held October 29 - November 1 in Madrid, Spain. Poster 1: Title: Efficacy of Buntanetap in Early AD and APOE4 Phase 2/3 Alzheimer’s Patients. Poster 2: Title: Biomarker Data Showed Buntanetap Reduced Neurotoxic Proteins, Improved Axonal Integrity, Reduced Inflammation, and Neuronal Functions in Alzheimer’s Clinical Studies. Find more information at: https://lnkd.in/edb3eFyJ CTAD Clinical Trials on Alzheimer's Disease #AlzheimersDisease #Alzheimers #AnnovisBio #Dementia #Biotech #Buntanetap

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📢 𝗡𝗲𝘄 𝘁𝗵𝗲𝗿𝗮𝗽𝗲𝘂𝘁𝗶𝗰 𝗽𝗼𝘀𝗶𝘁𝗶𝗼𝗻𝗶𝗻𝗴 𝗿𝗲𝗽𝗼𝗿𝘁𝘀 (𝗧𝗣𝗥𝘀) 𝗽𝘂𝗯𝗹𝗶𝘀𝗵𝗲𝗱 𝗶𝗻 𝗦𝗽𝗮𝗶𝗻: ⁣ ⁣ - 𝗔𝘅𝗶𝗰𝗮𝗯𝘁𝗮𝗴𝗲𝗻 𝗰𝗶𝗹𝗼𝗹𝗲𝘂𝗰𝗲𝗹 (Yescarta®) in treatment of adult patients with relapsed or refractory follicular lymphoma (FL) after three or more lines of systemic therapy.⁣ ⁣ Link: ⁣https://lnkd.in/d8YQBkHQ ⁣ - 𝗠𝗼𝘀𝘂𝗻𝗲𝘁𝘂𝘇𝘂𝗺𝗮𝗯 (Lunsumio®) in the treatment of relapsed or refractory follicular lymphoma (FL) who have received at least two prior systemic therapies.⁣ ⁣ Link:⁣ https://lnkd.in/dStPjtkP ⁣ - 𝗧𝗶𝘀𝗮𝗴𝗲𝗻𝗹𝗲𝗰𝗹𝗲𝘂𝗰𝗲𝗹 (Kymriah®) in the treatment of relapsed or refractory follicular lymphoma (FL) after two or more lines of systemic therapy in adult patients.⁣ ⁣ Link:⁣ https://lnkd.in/dzcQSTyD ⁣ - 𝗔𝘃𝗮𝗽𝗿𝗶𝘁𝗶𝗻𝗶𝗯 (Ayvakyt®) in the treatment of adult patients with unresectable or metastatic gastrointestinal stromal tumours carrying the D842V mutation of platelet-derived growth factor receptor alpha (PDGFRA).⁣ ⁣ Link:⁣ https://lnkd.in/dc8pEccn ⁣ - 𝗥𝗶𝘁𝗹𝗲𝗰𝗶𝘁𝗶𝗻𝗶𝗯 (Litfulo®) in severe alopecia areata.⁣ ⁣ Link:⁣ https://lnkd.in/djK9HJJY ⁣ - 𝗨𝗽𝗮𝗱𝗮𝗰𝗶𝘁𝗶𝗻𝗶𝗯 (Rinvoq®) for the treatment of moderate to severe active Crohn's disease in adult patients with inadequate response, loss of response or intolerance to conventional or biologic therapy.⁣ ⁣ Link: ⁣https://lnkd.in/dSUPDJTA ⁣ - 𝗥𝗶𝘀𝗮𝗻𝗸𝗶𝘇𝘂𝗺𝗮𝗯 (Skyrizi®) for the treatment of adult patients with moderately to severely active CD who have had an inadequate response, loss of response or intolerance to conventional therapy or a biologic drug.⁣ ⁣ Link:⁣ https://lnkd.in/dtRCJ9rg ⁣ - 𝗥𝗮𝘃𝘂𝗹𝗶𝘇𝘂𝗺𝗮𝗯 (Ultomiris®) in neuromyelitis optica spectrum disorder (NMOD). ⁣ ⁣ Link:⁣ https://lnkd.in/d53DgaSy ⁣ #Pharmaceuticals #TPR #AEMPS #MarketAccess #Spain

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Learn how to handle CMF cases with ease like Silvina Zabala Travers, MD does!

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📢 𝗢𝗺𝗮𝗸𝗮𝘀𝗲 𝗺𝗼𝗱𝗲𝗿𝗮𝘁𝗲𝘀 𝗸𝗲𝘆 𝗵𝗲𝗮𝗹𝘁𝗵𝗰𝗮𝗿𝗲 𝗱𝗲𝗯𝗮𝘁𝗲 𝗼𝗻 𝗶𝗻𝗻𝗼𝘃𝗮𝘁𝗶𝘃𝗲 𝘁𝗵𝗲𝗿𝗮𝗽𝘆 𝗮𝗰𝗰𝗲𝘀𝘀 𝗮𝗻𝗱 𝗿𝗲𝗶𝗺𝗯𝘂𝗿𝘀𝗲𝗺𝗲𝗻𝘁 𝗶𝗻 𝗦𝗽𝗮𝗶𝗻.⁣  ⁣ Omakase was thrilled to have participated moderating this great initiative under the sponsorship of Pierre Fabre and coordinated by Wecare-U on the necessary debate and ongoing work by c𝗲𝗻𝘁𝗿𝗮𝗹 𝗮𝗻𝗱 𝗿𝗲𝗴𝗶𝗼𝗻𝗮𝗹 𝗵𝗲𝗮𝗹𝘁𝗵𝗰𝗮𝗿𝗲 𝘀𝘆𝘀𝘁𝗲𝗺 𝘀𝘁𝗮𝗸𝗲𝗵𝗼𝗹𝗱𝗲𝗿𝘀 in Spain on 𝗸𝗲𝘆 𝗮𝘀𝗽𝗲𝗰𝘁𝘀 𝗿𝗲𝗴𝗮𝗿𝗱𝗶𝗻𝗴 𝗿𝗲𝗶𝗺𝗯𝘂𝗿𝘀𝗲𝗺𝗲𝗻𝘁 𝗮𝗻𝗱 𝗮𝗰𝗰𝗲𝘀𝘀 𝘁𝗼 𝗶𝗻𝗻𝗼𝘃𝗮𝘁𝗶𝘃𝗲 𝘁𝗵𝗲𝗿𝗮𝗽𝗶𝗲𝘀, including advanced therapies in Spain. ⁣ ⁣ Derived from the transposition of the EU Pharmaceutical legislation, we shall see many and impactful 𝗰𝗵𝗮𝗻𝗴𝗲𝘀 𝗶𝗻 𝗹𝗲𝗴𝗶𝘀𝗹𝗮𝘁𝗶𝗼𝗻 𝗮𝗻𝗱 𝗿𝗲𝗴𝘂𝗹𝗮𝘁𝗶𝗼𝗻𝘀 𝗶𝗻 𝗦𝗽𝗮𝗶𝗻 𝗶𝗻 𝘁𝗵𝗲 𝗳𝗼𝗿𝘁𝗵𝗰𝗼𝗺𝗶𝗻𝗴 𝗺𝗼𝗻𝘁𝗵𝘀, with the common objective to seek new formulas to incorporate 𝗱𝗶𝘀𝗿𝘂𝗽𝘁𝗶𝘃𝗲 𝗶𝗻𝗻𝗼𝘃𝗮𝘁𝗶𝗼𝗻 in a timely and adequate manner and obtain sought outcomes while ensuring the sustainability of the Spanish NHS system. Great efforts and advances have been and are being made.⁣  ⁣ The common will and vision are there.⁣  ⁣ 🔎Further information:⁣ https://lnkd.in/dKAkp-Es https://lnkd.in/d83JF4hq https://lnkd.in/dXskZbPb #Reimbursement #Access #Innovativetherapies #Advancedtherapies #Spain

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GO Norte Grupo Oncológico group has acknowledged APICES for its collaboration in the 𝗥𝗘𝗡𝗢 𝘀𝘁𝘂𝗱𝘆. ⁣ RENO study has been published in 𝘚𝘦𝘮𝘪𝘯𝘢𝘳𝘴 𝘪𝘯 𝘖𝘯𝘤𝘰𝘭𝘰𝘨𝘺. RENO is a retrospective observational study that describes the clinical characteristics, treatments, and health outcomes of patients with 𝗺𝗲𝘁𝗮𝘀𝘁𝗮𝘁𝗶𝗰 𝗿𝗲𝗻𝗮𝗹 𝗰𝗲𝗹𝗹 𝗰𝗮𝗿𝗰𝗶𝗻𝗼𝗺𝗮 in Northern Spain.⁣ APICES has collaborated in this study in data management and statistical analysis. We thank GO Norte Grupo Oncológico for trust APICES to cooperate this study and congratulate all the investigators and study teams involved in this study. ⁣ You can find further information in the following link:   https://lnkd.in/dqHk-9Py #clinicaltrials #Oncology #clinicalresearch #renalcarcinoma #CRO

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https://lnkd.in/gtainUYv   Article title: Impact of the “Omics Sciences” in Medicine: New Era for Integrative Medicine   Author(S): Noelia Clemente Plaza, Manuel Reig García-Galbis and Rosa María Martínez-Espinosa*   Journal: Journal of Clinical Microbiology and Biochemical Technology   Journal ISSN: 2581-527X Abstract: Background and objective: This work collects and analyses information about the evolution of medical practice during the last centuries. The main aim is to summarise new insights on “omics sciences” and their impact in medicine. Methods: Use of appropriate keywords, use of different engines of research information and the subsequent bibliometric analysis of the information. Results: The impact of the “omics sciences” in the early diagnosis of diseases is highly significant. Consequently, the implementation of “omics sciences” in medical practises contribute to the improvement of the monitoring and treatment of several diseases (particularly those based on molecular disorders). #Genomic #Transcriptomic #Proteomic #Metabolomics #Integrativemedicine #Personalizedmedicine   #CellularMicrobiology #EnvironmentalMicrobiology #MedicalMicrobiology #IndustrialMicrobiology #MarineMicrobiology #AquacultureMicrobiology #Bacteriology #Chlamydiology #Rickettsiology #Peertechz #PeertechzPublications #Mycobacteriology #AerobicActinomycetes #Mycology #Parasitology #Virology #ClinicalVeterinaryMicrobiology #Epidemiology #Biochemical #Endocytosis #Exocytosis #MembraneBiology #CellMigration #CellMatrix #OrganelleBiogenesis #Cytoskeleton #Proteolysis #CellDeath #CellCycle #CancerResearch #CellGrowth #CellDeath #CellDifferentiation #DrugTargets #GeneTherapy #DiseaseModels #Proteomics #StemCells #Bioenergetics #Mitochondria #FreeRadicals #RedoxSignaling #IonTransport #OxidativeStress #CellularMetabolism #XenobioticMetabolism #Metabolomics #CircadianControls #Hormones #Photosynthesis #CellSignaling #NitrogenFixation #PlantDisease #TransportProcesses #PlastidSystems #CellWallSynthesis #Phosphorylation #ProteinKinases #Phosphates #Ubiquitination #LipidSignaling #SecondMessengers #Cytokines #Receptors #GrowthFactors #GProteins #Integrins #NitricOxide #Enzymology #MolecularMechanisms #Biophysics #BiomolecularAssociations #SystemsBiology #ChemicalBiology #ProteinStructure #NucleicAcids #AminoAcids #DrugDesign #BiomolecularTargets #Lipids #Carbohydrates #EnvironmentalBiotechnology #MetabolicEngineering #TissueEngineering #Biodiversity #AgroBiotechnology #MedicalBiotechnology

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Join us tomorrow for an insightful webinar with Dr. Gerardo Chacón! 🦴🔬Discover strategic approaches to tackle challenging bone defects, from patient selection to flap management and biomaterial choices. Learn how to optimize outcomes and minimize complications in complex regenerative procedures. Don't miss this opportunity to enhance your clinical skills. Register at https://hubs.la/Q02N0_BB0 . #ContinuingEducation #RegenerativeDentistry #dentaleducation #implantdentistry

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The European strategy for Data Demonstration Spaces in #healthcare could become a great opportunity to develop a sustained demand in the industry: #benchmarking. #Processmining can contribute significantly, and we hope to explain an approach soon 🤞 A very interesting post from Asociación Salud Digital 👇 👇 👇

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📅 Mark your calendars! The new Abarca Prize winner will be revealed tomorrow. Are you curious to know which medical field and discovery is awarded in this IV Edition? 🌐 Discover more information at https://lnkd.in/dui-KFV #AbarcaPrize2024 #medicalresearch #medicine #award

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