CEO and Chairman, Microsoft — U.S. Satya Nadella has successfully led Microsoft through not one but two major transformations in his decade at the helm of the world’s largest software company: first, from PCs to the cloud, and now to AI. His prescien

WHEN VENTURE capitalist Jeremy Liew and his wife were dating, they talked about how one day they would take a year to travel the world. “That’s how we’d know we’d made it,” Liew says. He went on to become a partner at Lightspeed Venture Partners, and

If left untreated, Stargardt disease and Geographic Atrophy (late stage dry AMD) almost always lead to vision loss and blindness. A groundbreaking oral treatment in the last stage of clinical trials offers new hope. Dr. Tom Lin tells us more. Why did

MASAAKI NISHIKAWA PRESIDENT, SAISHUNKAN PHARMACEUTICAL CO., LTD. FOR MORE THAN 90 YEARS, SAISHUNKAN Pharmaceutical has aimed to create products that support skincare and well-being for the people of Japan. The firm takes inspiration from kampo, a tra

TRUMP BUMP Musk’s controversial decision to wade into politics helped him net our No. 1 spot. CEO and Founder, Tesla, SpaceX, xAI, and others — U.S. HIGH-STAKES RISK has been a hallmark of Elon Musk’s career: defying industry standards with reusable

OPEN FOR BUSINESS SpaceX is one of several Elon Musk enterprises that have planted stakes near Bastrop, Texas. OLD TEXAS … The streets in Bastrop’s historic downtown were laid out in the early 19th century. IT’S A 40-MINUTE DRIVE from Austin to the q

META’S NEW LENS Zuckerberg has pushed Meta to build Llama into all its products and services, including the Orion augmented-reality glasses (now in prototype stage). CEO, Chairman, and Founder, Meta — U.S. IT WAS THE SUMMER OF 2023, and the question

AROUND THE WORLD in 2024, voters chose change: in South Africa, France, Britain, and Japan. But nowhere does the anti-incumbent trend matter more than in the United States. The global uncertainty created by an oscillation of power between left and ri

OVER THE PAST several years, Big Tech firms like Google and Microsoft have trumpeted ambitious plans to go carbon-neutral, or even carbon-negative, by 2030. But then the generative-AI boom came along and threw a giant wrench in their plans. AI models

MOTHER LODE Molten gold is poured into bar molds at the Cortez refinery. SOME 1,350 FEET deep and two miles across at its widest point, the Cortez open-pit gold mine outside Elko, Nev., looks like an asteroid crater—the largest hole in the ground you

DIGITAL PLAYGROUND Users represented by their avatars connect via voice chat in a virtual game space on Roblox. With remote work here to stay, a collaboration-software maker thrives. U.S. INFORMATION TECHNOLOGY Amid the seemingly endless post-pandemi

PICKING STOCKS is about predicting the future. As investors can tell you, being early to spot a trend and betting on a company poised to ride it can translate to a handsome return. Those who bought Amazon in 1998, for example, or Tesla in 2012, or Nv

IN HIS 2012 ESSAY “Startup = Growth,” Paul Graham talks about a 5% to 7% weekly growth rate as table stakes for startup success. If you’re growing 10%, he says, you’re doing “exceptionally well.” What’s stayed with me most from that essay is the way

Companies built to adapt and thrive. THE GLOBAL ECONOMY in 2024 is a tale of two forces: optimism sparked by falling interest rates, and the uncertainty caused by geopolitical unrest. As companies focus on sustainable growth, such a volatile environm

IN NOVEMBER, Shayne Coplan had a week he’ll remember for the rest of his life: He got a phone call from the highest echelons at Mar-a-Lago. He went on TV for the first time. And his New York City apartment was raided by the FBI. The eventful few days

COMEBACK KING Palmer Luckey went from a painful ouster in Silicon Valley to the top of the private defense industry. PALMER LUCKEY, the founder of the $14 billion AI-powered weapons startup Anduril, has become the face of change in the defense indust

FOR GOLF ENTHUSIASTS, THE NEW YEAR DOESN’T BEGIN when the iconic ball drops in Times Square at midnight. It starts when PGA TOUR professionals tee it up on the lush greens of the Hawaiian Islands for the season-opening events. For more than a decade,

IN NOVEMBER 1996, Joe Bae had been working at buyout shop Kohlberg Kravis Roberts & Co. for six weeks as an analyst doing spadework on deals when Scott Nuttall, another recruit, moved into the office next door. Both Bae and Nuttall, who had each work

WHEN MY BONOBOS cofounder, Brian Spaly, and I had a falling-out in 2009, two years after starting the company, we made a strange decision. We decided that we would share the details of how our partnership fell apart with the community where our frien