pertussis also undergoes frequent structural rearrangement (6) that presents unique challenges to thorough investigation of genetic contributions to disease resurgence, limiting assessment of public health strategies.
The researchers found that geometric mean concentrations (GMCs) of neonatal cord
pertussis toxin antibodies from the Tdap-exposed group were 47.3 IU/mL versus 12.9 IU/mL in the Tdap-unexposed group.
The disease is registered among those who were not vaccinated against
pertussis and those who have not completed the full course of vaccination.
The Results: Of the total of 220 contacts who were tested for
pertussis, 86% of the households had at least one adult testing positive.
Pertussis data were collected from 1981 to 2015 from various sources including Annual Health Reports, (7) annual Ministry of Health (MOH) progress reports, ex.
The study also revealed that children ages 10 to 14 and who had been vaccinated against the disease were as susceptible to
pertussis as those who had never been vaccinated, which suggested that the vaccine's effectiveness wanes over time.
There are other reasons for the resurgence of
pertussis, he noted.
The company said the ARIES Bordetella Assay has been approved by the US FDA for direct detection and identification of Bordetella
pertussis (B.
Despite the fact that most countries have adopted extended vaccination programs against the disease,
pertussis continues to be a significant public health challenge.
Lessons learned: aP protection is less durable than originally thought, and much
pertussis is not in infants, but in the school-age and adolescent populations.