Table 1 Preservative permissible in the United States, European Union and Japan (22) Preservative Maximum allowable level Paraben Esters (including: 0.8% methylparaben, propylparaben, ethylparaben, butylparaben, isopropylparaben, isobutylparaben) Benzyl alcohol 1.0% Phenoxyethanol 1.0% Chlorhexidine 0.3% Chlorphenesin 0.3% (EU); 0.05% (Japan)
Dehydroacetic acid 0.6% (EU); 0.5% (Japan) Sorbic acid 0.6% (EU); 0.5% (Japan)
Resolution of the critical pair (
dehydroacetic acid and methylparaben) improved from 1.79 to 3.01 on the Agilent Poroshell 120 method, compared with the longer 5 [micro]m Agilent ZORBAX Eclipse Plus method.
Beauty Ingredients: Laracare A200 galactoarabinan; Natrulon RC-100 L-Carnitine; Natrulon H-10 polyglycerol; Polyaldo polyglycerol esters; Geogard ultra preservative (gluconolactone and sodium benzoate); Geogard 111 preservative (
dehydroacetic acid); Geogard 221 preservative (
dehydroacetic acid and benzyl alcohol); Glydant preservatives (DMDM hydantoin); Glydant plus liquid preservatives (DMDM Hydantoin & IPBC); Glycacil preservatives (IPBC)
(Phenoxyethanol (and) benzoic acid (and)
dehydroacetic acid)