Hydrocortisone

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hydrocortisone

[‚hī·drə′kȯrd·ə‚zōn]
(biochemistry)
C21H30O5 The generic name for 17-hydroxycorticosterone; an adrenocortical steroid occurring naturally and prepared synthetically; its effects are similar to cortisone, but it is more active. Also known as cortisol.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Hydrocortisone

 

(17-hydroxycorticosterone, cortisol), one of the glucocorticoids; a hormone formed in the adrenal cortex and predominantly regulating carbohydrate metabolism. The human adrenal glands secrete from 5 to 30 mg of hydrocortisone per day, although formation of hydrocortisone may increase five times under conditions of stress or upon introduction of adrenocorticotropic hormone.

Hydrocortisone is used in medical practice as a hormonal preparation that exerts an anti-inflammatory and antiallergic effect. Hydrocortisone (and hydrocortisone acetate in the form of a suspension) is prescribed for the treatment of rheumatism, bronchial asthma, leukemia, and endocrine and other diseases; it is used locally (most often in the form of a cream) for eczema, neurodermatitis, and eye diseases.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.