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Sterol carrier protein

From Wikipedia, the free encyclopedia
Sterol carrier protein 2
Identifiers
SymbolSCP2
PfamPF02036
InterProIPR003033
PROSITEPDOC00092
SCOP21qnd / SCOPe / SUPFAM
OPM superfamily135
OPM protein2cx7
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary

Sterol carrier proteins (also known as nonspecific lipid transfer proteins) is a family of proteins that transfer steroids and probably also phospholipids and gangliosides between cellular membranes.

These proteins are different from plant nonspecific lipid transfer proteins but structurally similar to small proteins of unknown function from Thermus thermophilus.

This domain is involved in binding sterols. The human sterol carrier protein 2 (SCP2) is a basic protein that is believed to participate in the intracellular transport of cholesterol and various other lipids.[1]

Human proteins containing this domain

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HSD17B4; HSDL2; SCP2; STOML1;

See also

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References

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  1. ^ Johansson J, Wuthrich K, Szyperski T, Scheek S, Assmann G, Seedorf U (1993). "NMR determination of the secondary structure and the three-dimensional polypeptide backbone fold of the human sterol carrier protein 2". FEBS Lett. 335 (1): 18–26. doi:10.1016/0014-5793(93)80431-S. PMID 8243660. S2CID 9969358.
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This article incorporates text from the public domain Pfam and InterPro: IPR003033