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Summary

Description
English: The signaling pathways involved in vascular mimicry are shown with their relevant components. Vascular signaling (purple) promotes the secretion of pro-migratory signals. Stem cell signaling (blue) promotes gene expression which de-differentiates the cell. Hypoxia (green) is involved throughout both pathways due to its downstream regulation of important cell signaling molecules.
Date
Source Delgado-Bellido D, Serrano-Saenz S, Fernández-Cortés M, Oliver FJ. Vasculogenic mimicry signaling revisited: focus on non-vascular VE-cadherin. Mol Cancer. 2017 Mar 21;16(1):65. doi: 10.1186/s12943-017-0631-x. PMID: 28320399; PMCID: PMC5359927..
Author Delgado-Bellido D, Serrano-Saenz S, Fernández-Cortés M, Oliver FJ.

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Captions

This figure details the major signaling pathways involved in vasculogenic mimicry.

Items portrayed in this file

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21 March 2017

image/jpeg

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current00:03, 13 November 2023Thumbnail for version as of 00:03, 13 November 2023567 × 417 (64 KB)KashydanUploaded a work by Delgado-Bellido D, Serrano-Saenz S, Fernández-Cortés M, Oliver FJ. from Delgado-Bellido D, Serrano-Saenz S, Fernández-Cortés M, Oliver FJ. Vasculogenic mimicry signaling revisited: focus on non-vascular VE-cadherin. Mol Cancer. 2017 Mar 21;16(1):65. doi: 10.1186/s12943-017-0631-x. PMID: 28320399; PMCID: PMC5359927.. with UploadWizard

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