Olprinone: Difference between revisions

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+{{Short description|Chemical compound}}
-{{orphan|date=January 2010}}
 {{Drugbox
+| Verifiedfields = changed
-| verifiedrevid = 444645873
+| Watchedfields = changed
-| IUPAC_name = 5-imidazo[2,1-f]pyridin-6-yl-6-methyl-2-oxo-1H-pyridine-3-carbonitrile
+| verifiedrevid = 451222122
-| image = Olprinone.png
+| IUPAC_name = 5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-1''H''-pyridine-3-carbonitrile
+| image = Olprinone.svg
 <!--Clinical data-->
 | tradename =
 | pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
-| pregnancy_US = <!-- A / B            / C / D / X -->
+| pregnancy_US = <!-- A / B / C / D / X -->
 | pregnancy_category =
-| legal_status = Rx-only. Not marketed in US and the EU
+| legal_status = Rx-only (<small>[[Japan|JP]]</small>). Not marketed in US and the EU
 | routes_of_administration = [[Intravenous therapy|IV]]
@@ Line 19: / Line 20: @@
 | metabolism =
 | elimination_half-life =
 | excretion =
 <!--Identifiers-->
+| CAS_number_Ref = {{cascite|correct|??}}
 | CAS_number = 106730-54-5
 | ATC_prefix =
@@ Line 31: / Line 33: @@
 | UNII_Ref = {{fdacite|correct|FDA}}
 | UNII = 4Y8BMI9YGC
+| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
+| ChemSpiderID = 4432
 <!--Chemical data-->
 | chemical_formula =
 | C=14 | H=10 | N=4 | O=1
+| smiles = Cc1[nH]c(=O)c(C#N)cc1-c1ccc2nccn2c1
-| molecular_weight = 250.25 g/mol
+| StdInChI_Ref = {{stdinchicite|changed|chemspider}}
-| smiles = CC1=C(C=C(C(=O)N1)C#N)C2=CN3C=CN=C3C=C2
+| StdInChI = 1S/C14H10N4O/c1-9-12(6-11(7-15)14(19)17-9)10-2-3-13-16-4-5-18(13)8-10/h2-6,8H,1H3,(H,17,19)
+| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}
+| StdInChIKey = JPAWFIIYTJQOKW-UHFFFAOYSA-N
 }}
-'''Olprinone''' ([[International Nonproprietary Name|INN]]) is a cardiotonic agent.<ref name="pmid7908977">{{cite journal |author=Uemura Y, Tanaka S, Ida S, Yuzuriha T |title=Pharmacokinetic study of loprinone hydrochloride, a new cardiotonic agent, in beagle dogs |journal=J. Pharm. Pharmacol. |volume=45 |issue=12 |pages=1077–81 |year=1993 |month=December |pmid=7908977 |doi= |url=}}</ref> It has been marketed in [[Japan]] since 1996.<ref>{{en icon}}{{cite web |url=http://di.eisai.co.jp/di/EPI/COR_A_EPI.pdf |title=Coretec Injection 5&nbsp;mg |date=April 2005 |publisher=[[Eisai Co.]] |accessdate=2008-06-26}} {{Dead link|date=October 2010|bot=H3llBot}}</ref>
+'''Olprinone''' ([[International Nonproprietary Name|INN]]) is a cardiotonic agent.<ref name="pmid7908977">{{cite journal |vauthors=Uemura Y, Tanaka S, Ida S, Yuzuriha T |title=Pharmacokinetic study of loprinone hydrochloride, a new cardiotonic agent, in beagle dogs |journal=J. Pharm. Pharmacol. |volume=45 |issue=12 |pages=1077–81 |date=December 1993 |pmid=7908977 |doi= 10.1111/j.2042-7158.1993.tb07184.x}}</ref> It has been marketed in [[Japan]] since 1996.<ref>{{in lang|en}}{{cite web |url=http://di.eisai.co.jp/di/EPI/COR_A_EPI.pdf |title=Coretec Injection 5&nbsp;mg |date=April 2005 |publisher=[[Eisai Co.]] |access-date=2008-06-26}} {{Dead link|date=October 2010|bot=H3llBot}}</ref>
 ==References==
 {{Reflist}}
+==External links==
+*{{Commonscatinline}}
 [[Category:Antianginals]]
-[[Category:Nitriles]]
+[[Category:Conjugated nitriles]]
 [[Category:Imidazopyridines]]
+[[Category:2-Pyridones]]