Talk:Selective serotonin reuptake inhibitor

• Archive01 (through May 2006)

Macro-effects

This article is pretty bad. Tons of focus on the side-effects, the criticism, the lawsuits, almost none on the actual effects of the drug. Not at a moluecular-biological level; I mean, cognitive effects--how does it make people feel? How does it treat social anxiety disorder, are people suddenly more outgoing? Most medication pages I've seen have included such information; it's highly pertient and, presumably, is sought by many Wikipedia-users.--70.17.209.58 07:03, 22 March 2007 (UTC)

Addition

I've tryed every SSRI / SNRI on the market to date on varying degrees of dosage for near 10 years for mild anxiety, Heres what i've found: SSRI's / SNRI's work by normalizing emotions. The higher the dose the more the overall emotion is regulated this is good for major problems such as losing a loved one but overall SSRI' / SNRIS will not do anything more than lower quality of life by making everything feel like a chore. Please read this and believe me a lower dose is good in some cases the larger the problem the larger the dose but DON'T stay on that same level try to taper this is not speculation I've tryed paxil, celexa, venafaxline, zoloft and many others.

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Generalizing your own individual experience to the overall profile of a drug's efficacy in large populations is not particularly useful to the discussion. Large doses do, in fact, benefit many patients over long-term usage, despite your own experiences.

Lack of quality

This article needs a good re-write. Too much is poorly written, uncited, speculative, and in some cases, clearly biased. Proper citation of scientific studies is essential; currently, it is sorely lacking. There is an enormous wealth of scientific information and research on SSRIs, and this article fails to take advantage of that body of knowledge. A good re-write is hereby requested, requested only of those people who have the capacity to cite diligently, back up claims, and write a non-biased, factual article. --Muugokszhiion 05:32, 10 May 2006 (UTC)

I agree with your assessment. Are you offering to take a lead? JFW | T@lk 13:07, 10 May 2006 (UTC)

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Just for the record, the user "Shibidee" has gone off and started his own "Post SSRI Sexual Dysfunction" page. I don't know if anyone wants to do anything about it or not... --AJ

• For the record, I started the page on Post SSRI Sexual Dysfunction not Shibidee ;-) James R. Skinner

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Have people just given up on editing this page or what?

bias

I sense a big bias against SSRIs, especially by the large number of edits by User:67.82.232.151[1]. He wrongfully removed pertinent information and added his own POV to it.[2] tsk... tsk... tsk... 05:38, 17 February 2007 (UTC)

Don't get me wrong - but aren't you the one that just removed the Robbie Williams reference from the Seroxat page? I have to ask why did you do that? It's simple matter of fact that he's checked himself into rehab... is the reference to "seroxat addiction" that you don't like? One might argue that the bias is with you rather than 67.82.232.15.

Please sign your comments. Use ~~~~. I removed it simply because it had no source. (WP:BLP). I see you've re-added it, but even so I don't think it belong. I don't think we should add every famous person troubles with drugs on the drug's page. On the person's article, fine. By looking at your edits, I can see you spreading your agenda around, like in Panorama (TV series). The show has been around for some 50 years and the bit you added is somehow extra special? Removed. 70.104.16.244 17:17, 19 February 2007 (UTC)

Hello- is there any way to substantiate this "Also, SSRIs may protect against neurotoxicity caused by other compounds (for instance MDMA and Fenfluramine)." It appears to be reckless and unfounded. As a physician, I can think of no mechanism that would explain this, and while I might be wrong, I think some scientific grounds must be provided before dangerously suggesting that SSRI compunds might help protect from some vague threat of MDMA induced brain damage. What kind of damage? How would it protect you? Is there any scicnce here at all?

St John's Wort = MAOI?

I have tagged this claim. It is not mentioned in the wikipedia articles for either St John's Wort or MAOI. A quick google search suggests that this is doubtful as a result of new studies that seem to disprove this. Fortnern 22:30, 23 April 2007 (UTC)

There have been incidents of Serotonin Syndrom when taking St John's Wort while taking an SSRI, and it looks like St John's was the culprit. I don't have a reference for this info, but it's probably good since my gf is a psychiatrist and I read her journals. Rlcuda 13:24, 14 June 2007 (UTC)

A studie that maybe is relevant in this discussion

http://medicine.plosjournals.org/archive/1549-1676/2/12/pdf/10.1371_journal.pmed.0020392-S.pdf Jaccmon 21:04, 16 May 2007 (UTC)

criticism statement not supported by cited source

The source[3] cited for the statement Several studies have been published demonstrating that SSRIs do not significantly outperform placebos at reducing depressive symptoms. These articles confirm..., is a single study - a meta-analysis, not "Several studies", and is identified as a "controversial one" in the editor's note accompanying it. so i don't think it supports the "Several" and "These articles" statement and i intend to change the text accordingly. Doldrums 22:18, 10 June 2007 (UTC)

Suggested Link

208.16.91.240 13:18, 14 June 2007 (UTC)