Phytantriol is an aliphatic alcohol used in cosmetic products and as a food additive.[1][2] At room temperature it is a viscous liquid that is colourless to light yellow and with a sweetish odour.[3][1]
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| Names | |
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| IUPAC name
3,7,11,15-Tetramethylhexadecane-1,2,3-triol
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| Other names
C20-triol, tetramethyl trihydroxyhexadecane, 3,7,11,15,-tetramethyl-1,2,3,-trihydroxyhexadecane, curasan, haircare complex, CLR, AEC phytantriol, PTL, C20-triole, panteen, PTR[1]
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| Identifiers | |
3D model (JSmol)
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| 1866094 | |
| ChEBI | |
| ECHA InfoCard | 100.070.818 |
| EC Number |
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PubChem CID
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| UNII | |
CompTox Dashboard (EPA)
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| Properties | |
| C20H42O3 | |
| Molar mass | 330.553 g·mol−1 |
| Appearance | Pale yellow or clear viscous liquid |
| Odor | sweetish |
| Density | 0.905 g/ml |
| Melting point | 5–10 °C (41–50 °F; 278–283 K) |
| Boiling point | 145 °C (1.45 ×10−5 psi) 300 °C (14.69 psi) |
| Soluble in water, ethanol, and propylene glycol | |
| Hazards | |
| GHS labelling: | |
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| Warning | |
| H315, H317, H413 | |
| P261, P264, P272, P273, P280, P302+P352, P321, P332+P313, P333+P313, P362, P363, P501 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Preparation
editPhytantriol is prepared by oxidizing isophytol in formic acid, hydrolysis of the product with an inorganic base, and isolation.[1]
Uses
editAs a cosmetic ingredient, phytantriol functions to increase moisture retention in skin and hair and helps vitamins and amino acids penetrate.[4] As of 2002 it is found in about 100 cosmetic products, such as hair conditioners, shampoos, and hair tonics, in concentrations from 0.0002% to 1%.[1]
Phytantriol is an amphiphile that is the second most used in making cubosomes.[5]
Toxicology
editSee also
editReferences
edit- ^ a b c d e f "Final report on the safety assessment of phytantriol". International Journal of Toxicology. 26 Suppl 1: 107–114. 27 January 2018. doi:10.1080/10915810601163947. PMID 17365138.
- ^ Mus-Veteau, Isabelle (2014). Membrane Proteins Production for Structural Analysis. Springer. p. 298. ISBN 9781493906628.
- ^ "Phytantriol" (PDF). DSM.
- ^ Barauskas, Justas; Landh, Tomas (November 2003). "Phase Behavior of the Phytantriol/Water System". Langmuir. 19 (23): 9562–9565. doi:10.1021/la0350812.
- ^ Schwarz, James A.; Contescu, Cristian I.; Putyera, Karol (2004). Dekker Encyclopedia of Nanoscience and Nanotechnology. CRC Press. p. 887. ISBN 9780824750473.