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Journal of Medical Sciences

Year: 2001 | Volume: 1 | Issue: 2 | Page No.: 44-47
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Authors

G. Sierra Galera

J. A. Prada Oliveira

M. Carmen Glez. Macias

C. Verastegui

Fco. J. Fdez- Trujillo

Keywords

Research Article

Histochemical Study of the Presence of Glycoproteins in the Skin-mucosa Transition Zone in Human Nasal Septum

G. Sierra Galera
Department of Morphological Sciences, Faculty of Medicine, University of Cádiz. Plaza Fragela s/n. 1 1 003. Cédiz. Spain
J. A. Prada Oliveira
Department of Morphological Sciences, Faculty of Medicine, University of Cádiz. Plaza Fragela s/n. 1 1 003. Cédiz. Spain
M. Carmen Glez. Macias
Department of Morphological Sciences, Faculty of Medicine, University of Cádiz. Plaza Fragela s/n. 1 1 003. Cédiz. Spain
C. Verastegui
Department of Morphological Sciences, Faculty of Medicine, University of Cádiz. Plaza Fragela s/n. 1 1 003. Cédiz. Spain
Fco. J. Fdez- Trujillo
Department of Morphological Sciences, Faculty of Medicine, University of Cádiz. Plaza Fragela s/n. 1 1 003. Cédiz. Spain
A group of horseradish peroxidase-conjugated lectins (Con-A, WGA, PNA, RCA-I, SBA, DBA, UEA-I) and the classical histochemical techniques to detect sialic acids were used to study the content and distribution of terminal sugar residues of glyco conjugated in the skin-mucosa transition zone in the nasal septum of healthy patients. This transition zone possesses a specific histological characteristic, where is changed a stratified epithelium first into a columnar and then into a pseudostratified one. The results showed a histochemical pattern in the basal cells of the epithelium similar to the common pattern in the epidermis, but different to the basal cells of the nasal mucosa. The transition zone possesses terminal residues rich in Nac-Glucosamine, neuroaminic acid, dimer Gal (1-3)-GalNac and N-acGlc and D-Glc/ D-Man.
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