The Role of Preoperative Platelet-to-Lymphocyte Ratio as a Predictor for Incisional Hernias after Hand-Assisted Laparoscopic Liver Surgery for Metastatic Colorectal Cancer
Abstract
:1. Introduction
2. Materials and Methods
2.1. Radiological Assessment of Incisional Hernia
2.2. Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Conflicts of Interest
References
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All Cohort (n = 89) | Patients with Incisional Hernia (n = 7) | Patients without Incisional Hernia (n = 82) | p | |
---|---|---|---|---|
Age | 65.1 ± 12.2 | 67.6 ± 15.4 | 64.9 ± 11.9 | 0.59 |
Gender | 0.46 | |||
Male | 50 (56.2%) | 3 (6%) | 47 (94%) | |
Female | 39 (43.8%) | 4 (10.3%) | 35 (89.7%) | |
Diabetes mellitus | 0.86 | |||
Yes | 23 (25.8%) | 2 (8.7%) | 21 (91.3%) | |
No | 66 (74.2%) | 5 (7.6%) | 61 (92.4%) | |
Smoking | 0.38 | |||
Yes | 15 (16.8%) | 2 (13.3%) | 13 (86.7%) | |
No | 74 (83.2%) | 5 (6.8%) | 69 (93.750 | |
BMI | 0.037 | |||
<25 | 33 (37.1%) | 0 (0%) | 33 (100%) | |
>25 | 56 (62.9%) | 7 (12.5%) | 49 (87.5%) | |
ASA | 0.49 | |||
2-1 | 63 (70.8%) | 6 (9.5%) | 57 (90.5%) | |
4-3 | 26 (29.2%) | 1 (3.8%) | 25 (96.2%) | |
No. of liver metastases (mean ± SD) | 1.76 ± 1.22 | 1.14 ± 0.38 | 1.81 ± 1.25 | 0.16 |
Size (mean ± SD) | 31 ± 4 | 23.77 ± 10 | 32.14 ± 4 | 0.12 |
Neoadjuvant chemotherapy | 0.67 | |||
Yes | ||||
No | 58 (65.2%) | 4 (6.9%) | 54 (93.1%) | |
31 (34.8%) | 3 (9.7%) | 28 (90.3%) | ||
Avastin | 0.91 | |||
Yes | 27 (30.3%) | 2 (7.4%) | 25 (92.6%) | |
No | 62 (69.7%) | 5 (8.1%) | 57 (91.9%) | |
Simultaneous colon resection | 0.016 | |||
Yes | ||||
No | 6 (6.7%) | 2 (33.3%) | 4 (66.7%) | |
83 (93.3%) | 5 (6%) | 78 (94%) | ||
EBL(mL) (mean ± SD) | 337.2 ± 327.84 | 385.71 ± 484.83 | 332.9+324.81 | 0.68 |
Blood transfusion | 0.97 | |||
Yes | 13 (14.6%) | 1 (7.7%) | 12 (92.3%) | |
No | 76 85.4%) | 6 (7.9%) | 70 (92.1%) | |
Postop complication | 0.79 | |||
Yes | 16 (18%) | 1 (6.3%) | 15 (93.8%) | |
No | 73 (82%) | 6 (8.2%) | 67 (91.8%) |
Entire Cohort (n = 89) | Patients with Incisional Hernia (n = 7) | Patients without Incisional Hernia (n = 82) | p | |
---|---|---|---|---|
Albumin | 0.45 | |||
<3.5 | 6 (6.7%) | 0 (0%) | 6 (100%) | |
>3.5 | 83 (93.2%) | 7 (8.4%) | 76 (81.5%) | |
NLR | 0.46 | |||
<2.5 | 52 (58.4%) | 5 (9.6%) | 47 (90.4%) | |
>2.5 | 37 (41.6%) | 2 (5.4%) | 35 (95.6%) | |
PLR | 0.09 | |||
<200 | 80 (89.9%) | 5 (6.3%) | 75 (93.8%) | |
>200 | 9 (10.1%) | 2 (22.2%) | 7 (77.8%) | |
PNI | 0.46 | |||
<52 | 52 (58.4%) | 5 (9.6%) | 47 (90.4%) | |
>52 | 37 (41.6%) | 2 (5.4%) | 35 (94.6%) | |
SSI | 0.27 | |||
<600 | 76 (85.4%) | 5 (6.6%) | 71 (93.4%) | |
>600 | 13 (14.6%) | 2 (15.4%) | 11 (84.6%) |
Univariate | Multivariate | |||
---|---|---|---|---|
p | HR | p | HR | |
Diabetes mellitus No vs. yes | 0.98 | 1.01 (0.18–5.59) | ||
Smoking No vs. yes | 0.16 | 3.43 (0.61–19.31) | ||
BMI <25 vs. >25 | 0.15 | 0.011 (0.00–5.62) | ||
ASA 1–2 vs. 3–4 | 0.5 | 2.08 (0.24–17.97) | ||
Simultaneous colon No vs. yes | 0.004 | 0.052 (0.007–0.38) | 0.03 | 0.1 (0.01–0.83) |
PLR <200 vs. >200 | 0.029 | 0.13 (0.02–0.81) | 0.04 | 0.11(0.01–0.97) |
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Mahamid, A.; Abu-Zaydeh, O.; Sawaied, M.; Goldberg, N.; Haddad, R. The Role of Preoperative Platelet-to-Lymphocyte Ratio as a Predictor for Incisional Hernias after Hand-Assisted Laparoscopic Liver Surgery for Metastatic Colorectal Cancer. J. Pers. Med. 2022, 12, 492. https://doi.org/10.3390/jpm12030492
Mahamid A, Abu-Zaydeh O, Sawaied M, Goldberg N, Haddad R. The Role of Preoperative Platelet-to-Lymphocyte Ratio as a Predictor for Incisional Hernias after Hand-Assisted Laparoscopic Liver Surgery for Metastatic Colorectal Cancer. Journal of Personalized Medicine. 2022; 12(3):492. https://doi.org/10.3390/jpm12030492
Chicago/Turabian StyleMahamid, Ahmad, Omar Abu-Zaydeh, Muneer Sawaied, Natalia Goldberg, and Riad Haddad. 2022. "The Role of Preoperative Platelet-to-Lymphocyte Ratio as a Predictor for Incisional Hernias after Hand-Assisted Laparoscopic Liver Surgery for Metastatic Colorectal Cancer" Journal of Personalized Medicine 12, no. 3: 492. https://doi.org/10.3390/jpm12030492