A Multimode Detection Platform for Biothiols Using BODIPY Dye-Conjugated Gold Nanoparticles
Abstract
:1. Introduction
2. Materials and Methods
2.1. General Techniques
2.2. Materials
2.3. Synthesis Procedures
2.3.1. Synthesis of DBDP
2.3.2. Synthesis of AuNP-DBDP Nanocomposite NC1
2.3.3. Synthesis of DBDP Nanoparticles
2.4. SERS-Based Detection of Biothiols
2.5. Cell Culture
2.6. Cellular Uptake Studies
3. Results
3.1. Nanocomposite Preparation and Characterization
3.2. Investigation of Biothiol Interaction and IDA Principle
3.3. Biothiol Detection under Physiological Conditions
3.4. SERS-Based Detection of Biothiols
3.5. Raman Mapping-Based Detection of Biothiols
3.6. Cellular Imaging Studies
3.7. Test Strips from NC1 for Biothiol Detection
4. Discussion
5. Conclusions
Supplementary Materials
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Kumar, P.P.P. A Multimode Detection Platform for Biothiols Using BODIPY Dye-Conjugated Gold Nanoparticles. Colorants 2024, 3, 214-228. https://doi.org/10.3390/colorants3030015
Kumar PPP. A Multimode Detection Platform for Biothiols Using BODIPY Dye-Conjugated Gold Nanoparticles. Colorants. 2024; 3(3):214-228. https://doi.org/10.3390/colorants3030015
Chicago/Turabian StyleKumar, Panangattukara Prabhakaran Praveen. 2024. "A Multimode Detection Platform for Biothiols Using BODIPY Dye-Conjugated Gold Nanoparticles" Colorants 3, no. 3: 214-228. https://doi.org/10.3390/colorants3030015