H2O2 Metabolism in Normal Thyroid Cells and in Thyroid Tumorigenesis: Focus on NADPH Oxidases
Abstract
:1. Introduction
2. Redox Enzymes in Thyroid Hormone Synthesis
2.1. Thyroid Peroxidase (TPO)
2.2. Dual Oxidases (DUOX1 and DUOX2)
3. NADPH Oxidases in Thyroid Pathologies
3.1. DUOX1/2 in Thyroid Dyshormonogenesis
3.2. DUOX1/2 in Thyroid Tumorigenesis
3.3. NADPH Oxidase 4 (NOX4)
NOX4 in Thyroid Tumorigenesis
4. The Thyrocyte Anti-Oxidant Defense System
5. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Szanto, I.; Pusztaszeri, M.; Mavromati, M. H2O2 Metabolism in Normal Thyroid Cells and in Thyroid Tumorigenesis: Focus on NADPH Oxidases. Antioxidants 2019, 8, 126. https://doi.org/10.3390/antiox8050126
Szanto I, Pusztaszeri M, Mavromati M. H2O2 Metabolism in Normal Thyroid Cells and in Thyroid Tumorigenesis: Focus on NADPH Oxidases. Antioxidants. 2019; 8(5):126. https://doi.org/10.3390/antiox8050126
Chicago/Turabian StyleSzanto, Ildiko, Marc Pusztaszeri, and Maria Mavromati. 2019. "H2O2 Metabolism in Normal Thyroid Cells and in Thyroid Tumorigenesis: Focus on NADPH Oxidases" Antioxidants 8, no. 5: 126. https://doi.org/10.3390/antiox8050126