Cisplatin resistance in non-small cell lung cancer cells is associated with an abrogation of cisplatin-induced G2/M cell cycle arrest
Fig 13
Signalling model for reduction of G2/M arrest in A549rCDDP2000 cells.
Preliminary signaling model to explain the lack of a G2/M arrest in resistant cells indicating significant protein changes after treatment comparing a) A549 and b) A549rCDDP2000 cells based on mRNA data (red arrows) or protein data (green arrows).
doi: https://doi.org/10.1371/journal.pone.0181081.g013