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Baicalin inhibits biofilm formation, attenuates the quorum sensing-controlled virulence and enhances Pseudomonas aeruginosa clearance in a mouse peritoneal implant infection model

Fig 10

Effects of baicalin on the survival of C. elegans infected with P. aeruginosa PAO1.

(A). Kaplan-Meier survival curve of P. aeruginosa-infected C. elegans. (B). Colony counts of P. aeruginosa PAO1 recovered from worms fed untreated and 256 μg/mL baicalin-treated P. aeruginosa. After 24 h, the nematodes were washed to remove bacteria from the integument and ruptured to recover bacteria from the digestive tracts. Bacterial loads were determined by plating on the appropriate selective medium and counting colonies. Data were obtained from three experiments.

Fig 10

doi: https://doi.org/10.1371/journal.pone.0176883.g010