HIV-Infected Spleens Present Altered Follicular Helper T Cell (Tfh) Subsets and Skewed B Cell Maturation
Fig 5
Splenic Tfh subset harbor high amount of HIV-1 DNA integration.
qRT-PCR quantification of HIV proviral DNA levels in GCTfh, Tfh, memory and naïve CD4+ T cell subsets isolated from splenocytes of five HIV+ ITP+ individuals as described in S1 Fig. Symbols represent individual samples: horizontal bars represent mean; and error bars show SEM. Statistics were obtained using the non parametric Mann-Whitney test *p<0.05, **p<0.005, ***p<0.001.
doi: https://doi.org/10.1371/journal.pone.0140978.g005