Population Genetic Analysis Reveals a High Genetic Diversity in the Brazilian Cryptococcus gattii VGII Population and Shifts the Global Origin from the Amazon Rainforest to the Semi-arid Desert in the Northeast of Brazil
Fig 4
Population structure analysis inferred using multilocus sequence genotypes of Cryptococcus gattii isolates recovered from Brazil and using K = 3 (A), and comparison of these isolates with isolates recovered from different continents using K = 4 (B).
Clusters of individuals based on prior-defined populations are referred according to the Brazilian States and/or Continent. Each vertical line represents one of the isolates included and each color (red, dark blue, dark green, and yellow) represents the most likely ancestry of each isolate from one of the three populations (A) or four populations (B). Individuals with multiple colours have admixed genotypes from the prior-defined populations. One clone per region was included, thus Figure A contains 100 isolates while Figure B contain 125 isolates. The taxa nomenclature includes AM: Amazonas, PA: Pará, PI: Piauí, RR: Roraima, BA: Bahia, ES: Espírito Santo, RJ: Rio de Janeiro, MS: Mato Grosso do Sul, AS: Asia, AU: Australia, AF: Africa, SA: South America, NA: North America, EU: Europe.
doi: https://doi.org/10.1371/journal.pntd.0004885.g004