Abstract

We demonstrate the depth-resolved and detailed ocular perfusion maps within retina and choroid can be obtained from an ultrahigh sensitive optical microangiography (OMAG). As opposed to the conventional OMAG, we apply the OMAG algorithm along the slow scanning axis to achieve the ultrahigh sensitive imaging to the slow flows within capillaries. We use an $840\mathrm{nm}$ system operating at an imaging rate of $400\text{\hspace{0.17em} frames}∕\mathrm{s}$ that requires $3\mathrm{s}$ to complete one 3D scan of $\sim 3\times 3{\mathrm{mm}}^2$ area on retina. We show the superior imaging performance of OMAG to provide functional images of capillary level microcirculation at different land-marked depths within retina and choroid that correlate well with the standard retinal pathology.

© 2010 Optical Society of America

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