Issue 18, 2009
From the journal:

Soft Matter

Hydrophilic elastomeric biomaterials based on resilin-like polypeptides†

Manoj B. Charati,a   Jamie L. Ifkovits,b   Jason A. Burdick,b   Jeffery G. Linhardtc  and  Kristi L. Kiick*a  

* Corresponding authors

a Department of Materials Science and Engineering, University of Delaware, Newark, DE 19716, USA
E-mail: [email protected]

b Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA

c Bausch & Lomb, 1400 North Goodman Street Rochester, NY 14609, USA

Abstract

The production of complex, yet well defined materials offers many opportunities in regenerative medicine, in which the mechanical and biological properties of the matrix must meet stringent requirements. Here we report the recombinant production of modular polypeptidic materials, based on the highly resilient protein resilin, which are equipped with multiple biologically active domains. The recombinant materials exhibit useful mechanical and cell adhesion behavior.

Graphical abstract: Hydrophilic elastomeric biomaterials based on resilin-like polypeptides

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Article information

DOI
https://doi.org/10.1039/B910980C
Article type
Communication
Submitted
04 Jun 2009
Accepted
22 Jul 2009
First published
05 Aug 2009

Soft Matter, 2009,5, 3412-3416

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Hydrophilic elastomeric biomaterials based on resilin-like polypeptides

M. B. Charati, J. L. Ifkovits, J. A. Burdick, J. G. Linhardt and K. L. Kiick, Soft Matter, 2009, 5, 3412 DOI: 10.1039/B910980C

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