About: Protriptyline

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Protriptyline, sold under the brand name Vivactil among others, is a tricyclic antidepressant (TCA), specifically a secondary amine, indicated for the treatment of depression and attention-deficit hyperactivity disorder (ADHD). Uniquely among most of the TCAs, protriptyline tends to be energizing instead of sedating, and is sometimes used for narcolepsy to achieve a wakefulness-promoting effect. TCAs including protriptyline are also used to reduce the incidence of recurring headaches such as migraine, and for other types of chronic pain.

Property Value
dbo:abstract
  • بروتريبتيلين (بالإنجليزية: Protriptyline)‏ هو دواء يُستعمل في علاج: * اضطراب عصابي (ar)
  • Protriptylin (Handelsnamen: Vivactil®, Concordin®) ist ein Arzneistoff aus der Gruppe der trizyklischen Antidepressiva. Es hemmt ähnlich stark wie Desipramin die Wiederaufnahme des Neurotransmitters Noradrenalin, ohne dabei nennenswerte sedierende Eigenschaften zu haben. Protriptylin wirkt zudem als FIASMA (funktioneller Hemmer der sauren Sphingomyelinase). Der Wirkstoff wurde 1962 von Merck & Co. patentiert. Verwendet wird das Hydrochlorid. (de)
  • Protriptyline, sold under the brand name Vivactil among others, is a tricyclic antidepressant (TCA), specifically a secondary amine, indicated for the treatment of depression and attention-deficit hyperactivity disorder (ADHD). Uniquely among most of the TCAs, protriptyline tends to be energizing instead of sedating, and is sometimes used for narcolepsy to achieve a wakefulness-promoting effect. TCAs including protriptyline are also used to reduce the incidence of recurring headaches such as migraine, and for other types of chronic pain. (en)
  • Protryptylina – organiczny związek chemiczny, trójpierścieniowy lek przeciwdepresyjny, amina II-rzędowa, silny inhibitor wychwytu zwrotnego noradrenaliny. Stosowany w leczeniu depresji z zahamowaniem psychoruchowym bez cech lęku i niepokoju. Zalecany do lecznictwa wyłącznie wewnątrzszpitalnego ze względu na możliwość wywołania podniecenia psychoruchowego, lęku, zaburzeń snu oraz tachykardii. (pl)
  • Protriptylin är ett antidepressivt medel, inte narkotikaklassat. Varunamn i Sverige för ämnet är Concordin. Medlet är numera avregistrerat. Denna läkemedels- eller farmakologi-relaterade artikel saknar väsentlig information. Du kan hjälpa till genom att lägga till den. (sv)
  • Protriptilina, vendida sob a marca comercial Vivactil entre outras, é um antidepressivo tricíclico (abreviados na literatura como TCA, do inglês tricyclic antidepressant), especificamente uma amina secundária, indicada para o tratamento de depressão e Transtorno do déficit de atenção com hiperatividade (TDAH) Unicamente entre a maioria dos TCAs, protriptilina tende a ser estimulante ao invés de sedativo, e às vezes é usada para narcolepsia para alcançar um efeito . TCAs incluindo protriptilina também são usados para reduzir a incidência de cefaleias recorrentes tais como enxaqueca, e para outros tipos de dor crônica. Este medicamento também pode ser usado para tratamento da apneia do sono junto com um . (pt)
dbo:alternativeName
  • Vivactyl, others (en)
dbo:bioavailability
  • 77.000000 (xsd:float)
dbo:casNumber
  • 1225-55-4 (hydrochloride)
  • 438-60-8
dbo:chEBI
  • 8597
dbo:chEMBL
  • 668
dbo:drugbank
  • DB00344
dbo:fdaUniiCode
  • 4NDU154T12
dbo:medlinePlus
  • a604025
dbo:pubchem
  • 4976
dbo:thumbnail
dbo:wikiPageExternalLink
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  • 5901072 (xsd:integer)
dbo:wikiPageLength
  • 30385 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1093990560 (xsd:integer)
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dbp:atcPrefix
  • N06 (en)
dbp:atcSuffix
  • AA11 (en)
dbp:bioavailability
  • 77 (xsd:integer)
dbp:c
  • 19 (xsd:integer)
dbp:casNumber
  • 438 (xsd:integer)
dbp:casSupplemental
  • 1225 (xsd:integer)
dbp:chebi
  • 8597 (xsd:integer)
dbp:chembl
  • 668 (xsd:integer)
dbp:chemspiderid
  • 4805 (xsd:integer)
dbp:drugbank
  • DB00344 (en)
dbp:eliminationHalfLife
  • -331200.0 (dbd:second)
dbp:excretion
  • Urine: 50% (en)
  • Feces: minor (en)
dbp:h
  • 21 (xsd:integer)
dbp:iupacName
  • 3 (xsd:integer)
dbp:iupharLigand
  • 7285 (xsd:integer)
dbp:legalStatus
  • Rx-only (en)
dbp:medlineplus
  • a604025 (en)
dbp:metabolism
dbp:n
  • 1 (xsd:integer)
dbp:pregnancyUs
  • C (en)
dbp:proteinBound
  • 92.0 (dbd:perCent)
dbp:pubchem
  • 4976 (xsd:integer)
dbp:routesOfAdministration
dbp:smiles
  • c3cc2ccc3 (en)
dbp:stdinchi
  • 1 (xsd:integer)
dbp:stdinchikey
  • BWPIARFWQZKAIA-UHFFFAOYSA-N (en)
dbp:synonyms
  • Amimethyline; Protriptyline hydrochloride; MK-240 (en)
dbp:title
dbp:titlestyle
  • background:#ccccff (en)
dbp:tradename
  • Vivactyl, others (en)
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  • 4 (xsd:integer)
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  • 200 (xsd:integer)
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rdfs:comment
  • بروتريبتيلين (بالإنجليزية: Protriptyline)‏ هو دواء يُستعمل في علاج: * اضطراب عصابي (ar)
  • Protriptylin (Handelsnamen: Vivactil®, Concordin®) ist ein Arzneistoff aus der Gruppe der trizyklischen Antidepressiva. Es hemmt ähnlich stark wie Desipramin die Wiederaufnahme des Neurotransmitters Noradrenalin, ohne dabei nennenswerte sedierende Eigenschaften zu haben. Protriptylin wirkt zudem als FIASMA (funktioneller Hemmer der sauren Sphingomyelinase). Der Wirkstoff wurde 1962 von Merck & Co. patentiert. Verwendet wird das Hydrochlorid. (de)
  • Protriptyline, sold under the brand name Vivactil among others, is a tricyclic antidepressant (TCA), specifically a secondary amine, indicated for the treatment of depression and attention-deficit hyperactivity disorder (ADHD). Uniquely among most of the TCAs, protriptyline tends to be energizing instead of sedating, and is sometimes used for narcolepsy to achieve a wakefulness-promoting effect. TCAs including protriptyline are also used to reduce the incidence of recurring headaches such as migraine, and for other types of chronic pain. (en)
  • Protryptylina – organiczny związek chemiczny, trójpierścieniowy lek przeciwdepresyjny, amina II-rzędowa, silny inhibitor wychwytu zwrotnego noradrenaliny. Stosowany w leczeniu depresji z zahamowaniem psychoruchowym bez cech lęku i niepokoju. Zalecany do lecznictwa wyłącznie wewnątrzszpitalnego ze względu na możliwość wywołania podniecenia psychoruchowego, lęku, zaburzeń snu oraz tachykardii. (pl)
  • Protriptylin är ett antidepressivt medel, inte narkotikaklassat. Varunamn i Sverige för ämnet är Concordin. Medlet är numera avregistrerat. Denna läkemedels- eller farmakologi-relaterade artikel saknar väsentlig information. Du kan hjälpa till genom att lägga till den. (sv)
  • Protriptilina, vendida sob a marca comercial Vivactil entre outras, é um antidepressivo tricíclico (abreviados na literatura como TCA, do inglês tricyclic antidepressant), especificamente uma amina secundária, indicada para o tratamento de depressão e Transtorno do déficit de atenção com hiperatividade (TDAH) Unicamente entre a maioria dos TCAs, protriptilina tende a ser estimulante ao invés de sedativo, e às vezes é usada para narcolepsia para alcançar um efeito . (pt)
rdfs:label
  • بروتريبتيلين (ar)
  • Protriptylin (de)
  • Protriptyline (en)
  • Protryptylina (pl)
  • Protriptilina (pt)
  • Protriptylin (sv)
rdfs:seeAlso
owl:sameAs
prov:wasDerivedFrom
foaf:depiction
foaf:isPrimaryTopicOf
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