About: P-site

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The P-site (for peptidyl) is the second binding site for tRNA in the ribosome. The other two sites are the A-site (aminoacyl), which is the first binding site in the ribosome, and the E-site (exit), the third. During protein translation, the P-site holds the tRNA which is linked to the growing polypeptide chain. When a stop codon is reached, the peptidyl-tRNA bond of the tRNA located in the P-site is cleaved releasing the newly synthesized protein. During the translocation step of the elongation phase, the mRNA is advanced by one codon, coupled to movement of the tRNAs from the ribosomal A to P and P to E sites, catalyzed by elongation factor EF-G.

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  • The P-site (for peptidyl) is the second binding site for tRNA in the ribosome. The other two sites are the A-site (aminoacyl), which is the first binding site in the ribosome, and the E-site (exit), the third. During protein translation, the P-site holds the tRNA which is linked to the growing polypeptide chain. When a stop codon is reached, the peptidyl-tRNA bond of the tRNA located in the P-site is cleaved releasing the newly synthesized protein. During the translocation step of the elongation phase, the mRNA is advanced by one codon, coupled to movement of the tRNAs from the ribosomal A to P and P to E sites, catalyzed by elongation factor EF-G. (en)
  • P位點(英文：P-site,P for peptidyl)是核醣體中tRNA的第二個結合位點。其他兩個位點分別是A位點(aminoacyl)，它是核醣體中的第一個結合位點，而E位點(exit)是第三個結合位點。在蛋白質轉譯過程中，P位點保留生長中的多肽鏈連接的tRNA。當到達終止密碼子時，位於P位點的tRNA的氨醯-tRNA鍵被裂解，釋放出新合成的蛋白質。在延伸(elongation)階段的易位(translocation)步驟中，mRNA前進一個密碼子，與tRNA從核醣體A到P和P到E的運動相關聯，這是由延伸因子EF-G催化的。 (zh)
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  • The P-site (for peptidyl) is the second binding site for tRNA in the ribosome. The other two sites are the A-site (aminoacyl), which is the first binding site in the ribosome, and the E-site (exit), the third. During protein translation, the P-site holds the tRNA which is linked to the growing polypeptide chain. When a stop codon is reached, the peptidyl-tRNA bond of the tRNA located in the P-site is cleaved releasing the newly synthesized protein. During the translocation step of the elongation phase, the mRNA is advanced by one codon, coupled to movement of the tRNAs from the ribosomal A to P and P to E sites, catalyzed by elongation factor EF-G. (en)
  • P位點(英文：P-site,P for peptidyl)是核醣體中tRNA的第二個結合位點。其他兩個位點分別是A位點(aminoacyl)，它是核醣體中的第一個結合位點，而E位點(exit)是第三個結合位點。在蛋白質轉譯過程中，P位點保留生長中的多肽鏈連接的tRNA。當到達終止密碼子時，位於P位點的tRNA的氨醯-tRNA鍵被裂解，釋放出新合成的蛋白質。在延伸(elongation)階段的易位(translocation)步驟中，mRNA前進一個密碼子，與tRNA從核醣體A到P和P到E的運動相關聯，這是由延伸因子EF-G催化的。 (zh)
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  • P-site (en)
  • P位點 (zh)
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