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Intracellular antibody-mediated degradation (IAMD) is a neutralization mechanism of intracellular antibody-mediated immunity whereby an effector protein, TRIM21, directs antibody bound virions to the proteasome where they are degraded. As yet, it has only been observed to act against the adenovirus but is likely to also be effective against other non-enveloped viruses.

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  • Der intrazelluläre Antikörper-vermittelte Abbau (engl. intracellular antibody-mediated degradation, IAMD) bezeichnet den intrazellulären Abbau von Antigenen nach Bindung eines Antikörpers. (de)
  • Intracellular antibody-mediated degradation (IAMD) is a neutralization mechanism of intracellular antibody-mediated immunity whereby an effector protein, TRIM21, directs antibody bound virions to the proteasome where they are degraded. As yet, it has only been observed to act against the adenovirus but is likely to also be effective against other non-enveloped viruses. (en)
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  • Der intrazelluläre Antikörper-vermittelte Abbau (engl. intracellular antibody-mediated degradation, IAMD) bezeichnet den intrazellulären Abbau von Antigenen nach Bindung eines Antikörpers. (de)
  • Intracellular antibody-mediated degradation (IAMD) is a neutralization mechanism of intracellular antibody-mediated immunity whereby an effector protein, TRIM21, directs antibody bound virions to the proteasome where they are degraded. As yet, it has only been observed to act against the adenovirus but is likely to also be effective against other non-enveloped viruses. (en)
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  • Intrazellulärer Antikörper-vermittelter Abbau (de)
  • Intracellular antibody-mediated degradation (en)
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