About: Arfaptin

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In molecular biology, the arfaptin domain is a protein domain which interacts with ARF1, a small GTPase involved in vesicle budding at the Golgi complex and immature secretory granules. The structure of arfaptin shows that upon binding to a small GTPase, arfaptin forms an elongated, crescent-shaped dimer of three-helix coiled-coils. The N-terminal region of ICA69 is similar to arfaptin.

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dbo:abstract
  • In molecular biology, the arfaptin domain is a protein domain which interacts with ARF1, a small GTPase involved in vesicle budding at the Golgi complex and immature secretory granules. The structure of arfaptin shows that upon binding to a small GTPase, arfaptin forms an elongated, crescent-shaped dimer of three-helix coiled-coils. The N-terminal region of ICA69 is similar to arfaptin. (en)
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  • Arfaptin
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  • 32115084 (xsd:integer)
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  • 1855 (xsd:nonNegativeInteger)
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  • 995784031 (xsd:integer)
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dbp:caption
  • crystal structure analysis of rac1-gdp complexed with arfaptin (en)
dbp:cdd
  • cd00011 (en)
dbp:interpro
  • IPR010504 (en)
dbp:name
  • Arfaptin (en)
dbp:pfam
  • PF06456 (en)
dbp:pfamClan
  • CL0145 (en)
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  • 1 (xsd:integer)
dbp:symbol
  • Arfaptin (en)
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rdfs:comment
  • In molecular biology, the arfaptin domain is a protein domain which interacts with ARF1, a small GTPase involved in vesicle budding at the Golgi complex and immature secretory granules. The structure of arfaptin shows that upon binding to a small GTPase, arfaptin forms an elongated, crescent-shaped dimer of three-helix coiled-coils. The N-terminal region of ICA69 is similar to arfaptin. (en)
rdfs:label
  • Arfaptin (en)
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