TAOK2

TAOK2
Dynodwyr
Cyfenwau	TAOK2, MAP3K17, PSK, PSK1, PSK1-BETA, TAO1, TAO2, TAO kinase 2, Tao2beta
Dynodwyr allanol	OMIM: 613199 HomoloGene: 74531 GeneCards: TAOK2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • nucleotide binding • protein kinase activity • kinase activity • protein serine/threonine kinase activity • mitogen-activated protein kinase kinase binding • ATP binding • MAP kinase kinase kinase activity • neuropilin binding • tau protein binding • tau-protein kinase activity Cydrannau o'r gell • integral component of membrane • cell projection • bilen • receptor complex • dendrite • nucleolus • Cytosgerbwd • cytoplasmic vesicle membrane • cnewyllyn cell • cytoplasm • cytosol • GO:0016023 cytoplasmic vesicle • actin cytoskeleton • axon • neuron projection • dendritic growth cone • axonal growth cone Prosesau biolegol • phosphorylation • protein targeting to membrane • response to stress • positive regulation of JNK cascade • cellular response to DNA damage stimulus • protein phosphorylation • focal adhesion assembly • stress-activated MAPK cascade • regulation of cell growth • regulation of cell shape • cell migration • actin cytoskeleton organization • positive regulation of stress-activated MAPK cascade • GO:0097285 apoptotic process • regulation of mitotic cell cycle • nervous system development • regulation of apoptotic process • mitotic G2 DNA damage checkpoint signaling • axonogenesis • GO:0072468 signal transduction • stress-activated protein kinase signaling cascade • positive regulation of protein autophosphorylation • activation of protein kinase activity • regulation of actin cytoskeleton organization • protein autophosphorylation • basal dendrite morphogenesis • basal dendrite arborization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9344	n/a
Ensembl	ENSG00000149930	n/a
UniProt	Q9UL54	n/a
RefSeq (mRNA)	NM_001252043 NM_004783 NM_016151	n/a
RefSeq (protein)	NP_001238972 NP_004774 NP_057235	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn TAOK2 yw TAOK2 a elwir hefyd yn TAO kinase 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 16, band 16p11.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TAOK2.

• PSK
• PSK1
• TAO1
• TAO2
• MAP3K17
• PSK1-BETA

Llyfryddiaeth

• "PSK, a novel STE20-like kinase derived from prostatic carcinoma that activates the c-Jun N-terminal kinase mitogen-activated protein kinase pathway and regulates actin cytoskeletal organization. ". J Biol Chem. 2000. PMID 10660600.
• "Comparative studies of a new subfamily of human Ste20-like kinases: homodimerization, subcellular localization, and selective activation of MKK3 and p38. ". Oncogene. 2003. PMID 13679851.
• "Prostate-derived sterile 20-like kinase 1-alpha induces apoptosis. JNK- and caspase-dependent nuclear localization is a requirement for membrane blebbing. ". J Biol Chem. 2007. PMID 17158878.
• "Prostate-derived sterile 20-like kinases (PSKs/TAOKs) phosphorylate tau protein and are activated in tangle-bearing neurons in Alzheimer disease. ". J Biol Chem. 2013. PMID 23585562.
• "TAO (thousand-and-one amino acid) protein kinases mediate signaling from carbachol to p38 mitogen-activated protein kinase and ternary complex factors.". J Biol Chem. 2003. PMID 12665513.