RHOB

RHOB
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2FV8
Dynodwyr
Cyfenwau	RHOB, ARH6, ARHB, MST081, MSTP081, RHOH6, ras homolog family member B
Dynodwyr allanol	OMIM: 165370 HomoloGene: 68377 GeneCards: RHOB
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleotide binding • GDP binding • GTP binding • GO:0001948, GO:0016582 protein binding • GO:0006184 GTPase activity • protein kinase binding Cydrannau o'r gell • cytosol • endosome • late endosome • bilen • late endosome membrane • focal adhesion • Cellbilen • early endosome • cleavage furrow • endosome membrane • extracellular exosome • cnewyllyn cell • intracellular anatomical structure • cytoplasm • cell cortex • cell division site • intracellular membrane-bounded organelle Prosesau biolegol • cell differentiation • regulation of cell migration • endosome to lysosome transport • endothelial tube morphogenesis • negative regulation of cell cycle • positive regulation of angiogenesis • positive regulation of endothelial cell migration • multicellular organism development • platelet activation • cell adhesion • negative regulation of cell migration • angiogenesis • Rho protein signal transduction • cellular response to ionizing radiation • protein transport • intracellular protein transport • regulation of small GTPase mediated signal transduction • cellular response to hydrogen peroxide • GO:0097285 apoptotic process • small GTPase mediated signal transduction • positive regulation of apoptotic process • GO:0015915 transport • mitotic cytokinesis • G protein-coupled receptor signaling pathway • actin filament organization • regulation of cell shape • cell migration • establishment or maintenance of actin cytoskeleton polarity • regulation of actin cytoskeleton organization • actin filament bundle assembly Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	388	n/a
Ensembl	ENSG00000143878	n/a
UniProt	P62745	n/a
RefSeq (mRNA)	NM_004040	n/a
RefSeq (protein)	NP_004031	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RHOB yw RHOB a elwir hefyd yn Ras homolog family member B (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 2, band 2p24.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RHOB.

• ARH6
• ARHB
• RHOH6
• MST081
• MSTP081

Llyfryddiaeth

• "RhoB Acts as a Tumor Suppressor That Inhibits Malignancy of Clear Cell Renal Cell Carcinoma. ". PLoS One. 2016. PMID 27384222.
• "RhoB controls endothelial barrier recovery by inhibiting Rac1 trafficking to the cell border. ". J Cell Biol. 2016. PMID 27138256.
• "RhoB determines tumor aggressiveness in a murine EGFRL858R-induced adenocarcinoma model and is a potential prognostic biomarker for Lepidic lung cancer. ". Clin Cancer Res. 2014. PMID 25320360.
• "Critical functions of RhoB in support of glioblastoma tumorigenesis. ". Neuro Oncol. 2015. PMID 25216671.
• "An isoprenylation and palmitoylation motif promotes intraluminal vesicle delivery of proteins in cells from distant species.". PLoS One. 2014. PMID 25207810.