DDX39B

DDX39B
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1T5I, 1T6N, 1XTI, 1XTJ, 1XTK
Dynodwyr
Cyfenwau	DDX39B, BAT1, D6S81E, UAP56, DEAD-box helicase 39B, DExD-box helicase 39B
Dynodwyr allanol	OMIM: 142560 HomoloGene: 48376 GeneCards: DDX39B
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleotide binding • GO:0008026 helicase activity • GO:0032403 protein-containing complex binding • U4 snRNA binding • ATP-dependent protein binding • GO:0001948, GO:0016582 protein binding • nucleic acid binding • hydrolase activity • ATP binding • U6 snRNA binding • ATP-dependent activity, acting on RNA • ATPase activity • identical protein binding • RNA binding Cydrannau o'r gell • cytoplasm • transcription export complex • nuclear matrix • U6 snRNP • spliceosomal complex • U4 snRNP • cnewyllyn cell • nucleoplasm • nuclear speck • nucleolus • GO:0009327 protein-containing complex Prosesau biolegol • mRNA splicing, via spliceosome • mRNA transport • negative regulation of DNA damage checkpoint • mRNA processing • viral mRNA export from host cell nucleus • positive regulation of translation • mRNA export from nucleus • positive regulation of DNA-templated transcription, elongation • spliceosomal complex assembly • RNA secondary structure unwinding • RNA splicing • positive regulation of DNA biosynthetic process • liver development • positive regulation of cell growth involved in cardiac muscle cell development • positive regulation of vascular associated smooth muscle cell proliferation • mRNA 3'-end processing • termination of RNA polymerase II transcription • RNA export from nucleus • GO:0015915 transport Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	7919	n/a
Ensembl	ENSG00000198563 ENSG00000225073 ENSG00000237889 ENSG00000229496 ENSG00000215425 ENSG00000235439 ENSG00000225859 ENSG00000230624	n/a
UniProt	Q13838	n/a
RefSeq (mRNA)	NM_004640 NM_080598	n/a
RefSeq (protein)	NP_004631 NP_542165	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn DDX39B yw DDX39B a elwir hefyd yn Spliceosome RNA helicase DDX39B a DExD-box helicase 39B (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 6, band 6p21.33.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn DDX39B.

• BAT1
• UAP56
• D6S81E

Llyfryddiaeth

• "UAP56- a key player with surprisingly diverse roles in pre-mRNA splicing and nuclear export. ". BMB Rep. 2009. PMID 19403039.
• "Binding of ATP to UAP56 is necessary for mRNA export. ". J Cell Sci. 2008. PMID 18411249.
• "Dissecting biochemical peculiarities of the ATPase activity of TcSub2, a component of the mRNA export pathway in Trypanosoma cruzi. ". Int J Biol Macromol. 2017. PMID 28212935.
• "The cellular RNA helicase UAP56 is required for prevention of double-stranded RNA formation during influenza A virus infection. ". J Virol. 2011. PMID 21680511.
• "A dual reporter approach to quantify defects in messenger RNA processing.". Anal Biochem. 2009. PMID 19733147.