BCL9

BCL9
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2GL7, 2VP7, 2VPB, 2VPD, 2VPE, 2VPG, 3SL9
Dynodwyr
Cyfenwau	BCL9, LGS, B-cell CLL/lymphoma 9, B cell CLL/lymphoma 9, transcription coactivator, BCL9 transcription coactivator
Dynodwyr allanol	OMIM: 602597 HomoloGene: 3191 GeneCards: BCL9
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • beta-catenin binding • GO:0001948, GO:0016582 protein binding • GO:0001105 transcription coactivator activity Cydrannau o'r gell • cytoplasm • cis-Golgi network • Golgi apparatus • cnewyllyn cell • nucleoplasm • beta-catenin-TCF complex Prosesau biolegol • skeletal muscle cell differentiation • canonical Wnt signaling pathway • Wnt signaling pathway • somatic stem cell population maintenance • myotube differentiation involved in skeletal muscle regeneration • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • regulation of transforming growth factor beta receptor signaling pathway • beta-catenin-TCF complex assembly Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	607	n/a
Ensembl	ENSG00000116128	n/a
UniProt	O00512	n/a
RefSeq (mRNA)	NM_004326	n/a
RefSeq (protein)	NP_004317	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn BCL9 yw BCL9 a elwir hefyd yn B-cell CLL/lymphoma 9 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1q21.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn BCL9.

• LGS

Llyfryddiaeth

• "Differentially expressed microRNA-218 modulates the viability of renal cell carcinoma by regulating BCL9. ". Mol Med Rep. 2016. PMID 27314976.
• "Association study of BCL9 gene polymorphism rs583583 with schizophrenia and negative symptoms in Japanese population. ". Sci Rep. 2015. PMID 26494551.
• "Expression profiling of in vivo ductal carcinoma in situ progression models identified B cell lymphoma-9 as a molecular driver of breast cancer invasion. ". Breast Cancer Res. 2015. PMID 26384318.
• "Common variants in the BCL9 gene conferring risk of schizophrenia. ". Arch Gen Psychiatry. 2011. PMID 21383261.
• "BCL9 promotes tumor progression by conferring enhanced proliferative, metastatic, and angiogenic properties to cancer cells.". Cancer Res. 2009. PMID 19738061.